scholarly journals Metabolic complications of obesity

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
R Mizouri ◽  
M Khiari ◽  
F Boukhayatia ◽  
K Ben Naceur ◽  
R Ben Othman ◽  
...  

Abstract Background Obesity, through its numerous complications, influences the functional and vital prognosis, especially in situations of massive or morbid obesity. The aim of our study was to study the metabolic complications associated with obesity. Methods This was a descriptive cross-sectional study carried out in the first half of 2018 involving 100 obese patients attending the Obesity Unit of the National Institute of Nutrition in Tunis. Each patient received a complete clinical examination with a standard biological assessment. Obesity is defined by a body mass index ≥ 30 Kg / m2. Results The average age of our patients was 45.08 ± 13.9 years with a female predominance of 88%. The average weight was 103.76 ± 17.9 Kg. The average BMI was 38.95 ± 5.72 Kg / m2. The average waist circumference was 123.88 ± 13.13 cm and the average fat mass was 45.98 ± 12.22 kg. Twenty percent of our population was diabetic with an average duration of progression of 6.6. ± 4.04 years. The prevalence of dyslipidemia was high in morbidly obese patients with a rate of 18.6% compared to moderate to severe obesity at 6.4%. Arterial hypertension was noted in 33% of our population. The presence of moderate sleep apnea syndrome was noted in 31.3% of cases. Hyperuricemia was found in 8.6% of cases. Rheumatologic complications were marked by gonalgia in 26% of cases and low back pain in 6.8% of our patients. Conclusions Screening for complications related to obesity is necessary and essential for the comprehensive care of the obese person. Their treatment must be specific and it should not be limited to weight loss. Key messages Obesity. Metabolic complications.

Author(s):  
VICTOR MARTINS FERNANDES ◽  
GIBRAN RIBEIRO DA ROCHA ◽  
THIAGO CARVALHO MILET ◽  
DANIEL MATOS BARRETO ◽  
JORGE FARIA DE MIRANDA SANTOS ◽  
...  

ABSTRACT Introduction: obstructive Sleep Apnea Syndrome (OSAS) is a serious confition that compromises the quality of life and survival of patients. Its main risk fator in adults is obesity and the gold standard test for diagnosis is polysomnography (PSG), mainly through the apneia-hypopnea index (AHI). Objective: to analyze the sleep pattern of obese patients with indication for bariatric surgery, determining the main polisomnographic parameters compromised by obesity. Methods: This work is a cross-sectional study with analysis of polysomnography perfomed in patients with obesity in the peroperative period of bariatric surgery at a clinic in Vitória da Conquista/BA during 2017. The Epi Info 7 platform was used for analysis of the data. Results: 58 polysomnographic reports were analyzed, with 56,9% morbdly obese and 43,1% non-morbid. The prevalence of OSAS was 70,68% and de AHI ranged from zero to 84,6 with a mean of 19,47±22,89 e/h. morbidly obese, compared to “non-morbid”, had a longer saturation time below 80% and 90% (0,4±0,93 vs. 0,12±0,45 e 4,87±7,38 vs. 1,36±2,87 respectively; p-value=0,02 in both), worse index respiratory disorders ((29,24±25,36 vs. 16,88±16,21; p-value=0,02), higher AHI (24,71±25,68 vs. 12,56±16,67; p-value=0,02), higher hypopnea index values (16,41±17,10 vs. 6,99±8,52; p-value=0,006) and lower minimum saturation (78,24±9,80 vs. 85,24±6,33; p-value=0,004). Conclusions: the high prevalence of OSAS found confirms its indication in the preoperative period of bariatric surgery. The main respiratory event involved in most individuals with OSAS was the hypopnea index.


2016 ◽  
Vol 87 (7) ◽  
pp. 772-782 ◽  
Author(s):  
Silvia H. C. Sales-Peres ◽  
Francisco C. Groppo ◽  
Lida V. Rojas ◽  
Matheus de C. Sales-Peres ◽  
Arsenio Sales-Peres

2011 ◽  
Vol 66 (1) ◽  
pp. 83-90 ◽  
Author(s):  
L K Johnson ◽  
D Hofsø ◽  
E T Aasheim ◽  
T Tanbo ◽  
K B Holven ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Astrid van Huisstede ◽  
Manuel Castro Cabezas ◽  
Erwin Birnie ◽  
Gert-Jan M. van de Geijn ◽  
Arjan Rudolphus ◽  
...  

Background. Obesity and asthma are associated. There is a relationship between lung function impairment and the metabolic syndrome. Whether this relationship also exists in the morbidly obese patients is still unknown.Hypothesis. Low-grade systemic inflammation associated with the metabolic syndrome causes inflammation in the lungs and, hence, lung function impairment.Methods. This is cross-sectional study of morbidly obese patients undergoing preoperative screening for bariatric surgery. Metabolic syndrome was assessed according to the revised NCEP-ATP III criteria.Results. A total of 452 patients were included. Patients with the metabolic syndrome (n=293) had significantly higher blood monocyte (mean 5.3 versus 4.9,P=0.044) and eosinophil percentages (median 1.0 versus 0.8,P=0.002), while the total leukocyte count did not differ between the groups. The FEV1/FVC ratio was significantly lower in patients with the metabolic syndrome (76.7% versus 78.2%,P=0.032). Blood eosinophils were associated with FEV1/FVC ratio (adj. B −0.113,P=0.018).Conclusion. Although the difference in FEV1/FVC ratio between the groups is relatively small, in this cross-sectional study, and its clinical relevance may be limited, these data indicate that the presence of the metabolic syndrome may influence lung function impairment, through the induction of relative eosinophilia.


2008 ◽  
Vol 87 (2) ◽  
pp. 362-369 ◽  
Author(s):  
Erlend T Aasheim ◽  
Dag Hofsø ◽  
Jøran Hjelmesæth ◽  
Kåre I Birkeland ◽  
Thomas Bøhmer

Obesity Facts ◽  
2020 ◽  
pp. 1-8
Author(s):  
Hinrich Köhler ◽  
Valentin Markov ◽  
Anna Watschke ◽  
Kerstin Gruner-Labitzke ◽  
Clara Böker ◽  
...  

<b><i>Background:</i></b> Obesity is associated with a higher risk of work disability and premature early retirement. <b><i>Objective:</i></b> The aim of this study was to examine psychosocial predictors for work ability prior to surgery. <b><i>Methods:</i></b> Based on a sample of 197 surgery-seeking obese patients (preoperative body mass index [BMI] above 35 kg/m<sup>2</sup>) from a German bariatric surgery unit, the present cross-sectional study examined based on standardized self-rating measures whether depressive symptoms, dysfunctional eating behaviors, relationship satisfaction, and life satisfaction have a predictive value for work ability. <b><i>Results:</i></b> Considerable impairment of work ability was found in 51.8% of morbidly obese participants (<i>n</i> = 102). Multiple regression analyses revealed that older age, greater depressive symptoms, and lower life satisfaction were significant predictors of preoperative work ability. BMI, gender, relationship satisfaction, and dysfunctional eating behaviors did not predict work ability. <b><i>Conclusions:</i></b> Our findings might indicate the use of further psychosocial measures following bariatric surgery to increase work ability.


2019 ◽  
Vol 23 (4) ◽  
pp. 1123-1132 ◽  
Author(s):  
Ricardo L. M. Duarte ◽  
Fernanda C. Q. Mello ◽  
Flavio J. Magalhães-da-Silveira ◽  
Tiago S. Oliveira-e-Sá ◽  
Marcelo F. Rabahi ◽  
...  

2017 ◽  
Vol 135 (4) ◽  
pp. 332-338 ◽  
Author(s):  
Letícia Baltieri ◽  
Luiz Claudio Martins ◽  
Everton Cazzo ◽  
Débora Aparecida Oliveira Modena ◽  
Renata Cristina Gobato ◽  
...  

ABSTRACT CONTEXT AND OBJECTIVE: The combined effect of obesity and asthma may lead to significant impairment of quality of life (QOL). The aim here was to evaluate the prevalence of asthma among obese individuals, characterize the severity of impairment of quality of life and measure its relationship with pulmonary function. DESIGN AND SETTING: Observational cross-sectional study in public university hospital. METHODS: Morbidly obese individuals (body mass index &gt; 40 kg/m2) seen in a bariatric surgery outpatient clinic and diagnosed with asthma, were included. Anthropometric data were collected, the Standardized Asthma Quality of Life Questionnaire (AQLQ(S)) was applied and spirometry was performed. The subjects were divided into two groups based on the median of the score in the questionnaire (worse &lt; 4 and better &gt; 4) and were compared regarding anthropometric data and pulmonary function. RESULTS: Among the 4791 individuals evaluated, 219 were asthmatic; the prevalence of asthma was 4.57%. Of these, 91 individuals were called to start multidisciplinary follow-up during the study period, of whom 82 answered the questionnaire. The median score in the AQLQ(S) was 3.96 points and, thus, the individuals were classified as having moderate impairment of their overall QOL. When divided according to better or worse QOL, there was a statistically difference in forced expiratory flow (FEF) 25-75%, with higher values in the better QOL group. CONCLUSION: The prevalence of asthma was 4.57% and QOL was impaired among the asthmatic obese individuals. The worst QOL domain related to environmental stimuli and the best QOL domain to limitations of the activities. Worse QOL was correlated with poorer values for FEF 25-75%.


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