scholarly journals Energy and Fatigue Predict Gait Speed and Mood Decline: Results From the Health, Aging and Body Composition Study

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 371-371
Author(s):  
Xiaonan Zhu ◽  
Nancy W Glynn ◽  
Caterina Rosano ◽  
Rebecca Ehrenkranz

Abstract Older adults may report high energy alongside tiredness or vice versa; little is known about whether discordant self-reported energy (SEL) and tiredness predict trajectories of mood, cognition, or gait speed. SEL (0-10 scale dichotomized at median) and tiredness (present/absent) were obtained in 2,613 older adults (aged 74.6± 2.87 years) and used to create four groups (energized/not tired, low energy/tired, energized/tired, low energy/not tired). Center for Epidemiologic Studies Depression Scale (CES-D) and gait speed were measured over 10 years; mixed effect models compared trajectories in these domains across each group with low energy/tired group as referent. Each group was significantly associated with CES-D and gait. Adjusting for demographics, the high SEL/not tired group showed the least decline in mood (ß = -0.17, p<0.01); the high SEL/tired group showed the least decline in rapid gait (ß = 0.008, p = 0.02). High SEL may indicate resilience for mood and gait speed decline.

2007 ◽  
Vol 29 (3-4) ◽  
pp. 156-162 ◽  
Author(s):  
Marco Inzitari ◽  
Anne B. Newman ◽  
Kristine Yaffe ◽  
Robert Boudreau ◽  
Nathalie de Rekeneire ◽  
...  

2019 ◽  
Vol 74 (10) ◽  
pp. 1657-1663 ◽  
Author(s):  
Wei Duan-Porter ◽  
Tien N Vo ◽  
Kristen Ullman ◽  
Lisa Langsetmo ◽  
Elsa S Strotmeyer ◽  
...  

Abstract Background Hospitalization-associated functional decline is a common problem for older adults, but it is unclear how hospitalizations affect physical performance measures such as gait speed. We sought to determine hospitalization-associated change in gait speed and likelihood of new limitations in mobility and activities of daily living (ADLs). Methods We used longitudinal data over 5 years from the Health, Aging and Body Composition Study, a prospective cohort of black and white community-dwelling men and women, aged 70–79 years, who had no limitations in mobility (difficulty walking 1/4 mile or climbing 10 steps) or ADLs (transferring, bathing, dressing, and eating) at baseline. Gait speed, and new self-reported limitations in mobility and ADLs were assessed annually. Selected participants (n = 2,963) had no limitations at the beginning of each 1-year interval. Hospitalizations were self-reported every 6 months and verified with medical record data. Generalized estimating equations were used to examine hospitalization-associated change in gait speed and odds of new limitations over each 1-year interval. Fully adjusted models included demographics, hospitalization within the past year, health conditions, symptoms, body mass index, and health-related behaviors. Results In fully adjusted models, any hospitalization was associated with decrease in gait speed (−0.04 m/s; 95% confidence interval [CI]: −0.05 to −0.03) and higher odds of new limitations in mobility or ADLs (odds ratio = 1.97, 95% CI: 1.70–2.28), and separately with increased odds of new mobility limitation (odds ratio = 2.22, 95% CI: 1.90–2.60) and new ADL limitations (odds ratio = 1.84, 95% CI: 1.53–2.21). Multiple hospitalizations within a year were associated with gait speed decline (−0.06 m/s; 95% CI: −0.08 to −0.04) and greater odds of new limitations in mobility or ADLs (odds ratio = 2.96, 95% CI: 2.23–3.95). Conclusions Functionally independent older adults experienced hospitalization-associated declines in gait speed and new limitations in mobility and ADLs.


2012 ◽  
Vol 68 (4) ◽  
pp. 456-464 ◽  
Author(s):  
D. K. White ◽  
T. Neogi ◽  
M. C. Nevitt ◽  
C. E. Peloquin ◽  
Y. Zhu ◽  
...  

2016 ◽  
Vol 71 (12) ◽  
pp. 1688-1694 ◽  
Author(s):  
Michelle C. Odden ◽  
Chenkai Wu ◽  
Michael G. Shlipak ◽  
Bruce M. Psaty ◽  
Ronit Katz ◽  
...  

Author(s):  
Yujia (Susanna) Qiao ◽  
Theresa Gmelin ◽  
Sharon W Renner ◽  
Robert M Boudreau ◽  
Sarah Martin ◽  
...  

Abstract Background Lower physical activity levels and greater fatigability contribute independently to slower gait speed in older adults. To fully understand the bidirectional relations between physical activity and fatigability, and to inform potential intervention strategies, we examined whether physical activity or fatigability explains more of the other factor’s association on slower gait speed. Methods Two generations (probands and offspring) of older adults (N = 2079, mean age 73.0 ± 10.0 years, 54.2% women, 99.7% White) enrolled in the Long Life Family Study were assessed at Visit 2 (2014–2017). Self-reported physical activity was measured with the Framingham Physical Activity Index and perceived physical fatigability using the Pittsburgh Fatigability Scale. Statistical mediation analyses were conducted separately by generation with linear mixed-effect models accounting for family relatedness and adjusted for demographics, health conditions, and field center. Results Greater perceived physical fatigability explained the association of lower physical activity on slower gait speed via a 22.5% attenuation of the direct association (95% confidence interval [CI]: 15.0%–35.2%) for the probands and 39.5% (95% CI: 22.8%–62.6%) for the offspring. Whereas lower physical activity explained the association of greater perceived fatigability on slower gait speed via a 22.5% attenuation of the direct association (95% CI: 13.4%–32.8%) for the probands and 6.7% (95% CI: 3.8%–15.4%) for the offspring. Conclusions Our findings suggest that the impact of greater perceived physical fatigability on the association between lower physical activity and slower gait speed differs between younger-old and middle-to-oldest-old adults, indicating perceived physical fatigability as a potential mediator in the disablement pathway.


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