scholarly journals Sex differences in Speech and High-frequency Hearing Loss Association With Cognitive Impairment Among Older Adults

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 716-716
Author(s):  
Wang Jingru ◽  
Yu Ying ◽  
Guo Qi
Keyword(s):  
Hearing Loss ◽  
Cognitive Impairment ◽  
Confidence Interval ◽  
High Frequency ◽  
Pure Tone ◽  
Community Dwelling ◽  
World Health ◽  
High Frequency Hearing Loss ◽  
Hearing Sensitivity ◽  
Community Dwellers

Abstract Objectives The purpose of this study was to investigate the relationship between speech-frequency hearing loss (SFHL), high-frequency hearing loss (HFHL), and cognitive impairment (CI). Then to determine whether there are any differences in gender among older community dwellers in China. Methods This study involved 1,012 adults aged ≥60 years (428 male; average age, 72.61±5.51 years). The participants had their hearing and cognition measured using pure tone audiometry and Mini Mental State Examination (MMSE), respectively. We used the audiometric definition of hearing loss (HL) adopted by the World Health Organization (WHO). Speech-frequencies were measured as 0.5 kHz, 1 kHz, 2 kHz, and 4 kHz; high-frequencies were measured as 4 kHz and 8 kHz. Pure tone average (PTA) was measured as hearing sensitivity. Results Our studies demonstrated a 37.6% prevalence of HL in males and a 36.0% prevalence of HL in females. Adjusted for confounding variables, the results from a multivariate analysis showed that SFHL was associated with CI in females (OR=2.400, 95% Confidence Interval=1.313–4.385) and males (OR=2.189, 95% Confidence Interval=0.599–2.944). However, HFHL was associated with CI only in females (OR=2.943, 95% Confidence Interval=1.505–5.754). HL was associated with poorer cognitive scores (P<0.05). “Registration” (P<0.05) in MMSE was associated with speech and high-frequency hearing sensitivity. Conclusion The associations between HL and CI varied according to gender in older community-dwellers, suggesting that different mechanisms are involved in the etiology of HL. Moreover, hearing sensitivity was negatively associated with cognition scores; therefore, early screening for HL and CI among older community-dwelling adults is advised.

scholarly journals Gender-Specific Associations of Speech-Frequency Hearing Loss, High-Frequency Hearing Loss, and Cognitive Impairment Among Older Community Dwellers in China

2021 ◽  
Author(s):  
Jingru Wang ◽  
Feng Wang ◽  
Peipei Han ◽  
Yuewen Liu ◽  
Weibo Ma ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Cognitive Impairment ◽  
Confidence Interval ◽  
High Frequency ◽  
Pure Tone ◽  
Community Dwelling ◽  
World Health ◽  
High Frequency Hearing Loss ◽  
Hearing Sensitivity ◽  
Community Dwellers

Abstract Objectives The purpose of this study was to investigate the relationship between speech-frequency hearing loss (SFHL), high-frequency hearing loss (HFHL), and cognitive impairment (CI). Then to determine whether there are any differences in gender among older community dwellers in China. Methods This study involved 1,012 adults aged ≥ 60 years (428 male; average age, 72.61 ± 5.51 years). The participants had their hearing and cognition measured using pure tone audiometry and Mini Mental State Examination (MMSE), respectively. We used the audiometric definition of hearing loss (HL) adopted by the World Health Organization (WHO). Speech-frequencies were measured as 0.5 kHz, 1 kHz, 2 kHz, and 4 kHz; high-frequencies were measured as 4 kHz and 8 kHz. Pure tone average (PTA) was measured as hearing sensitivity. Results Our studies demonstrated a 37.6% prevalence of HL in males and a 36.0% prevalence of HL in females. Adjusted for confounding variables, the results from a multivariate analysis showed that SFHL was associated with CI in females (OR = 2.400, 95% Confidence Interval = 1.313–4.385) and males (OR = 2.189, 95% Confidence Interval = 0.599–2.944). However, HFHL was associated with CI only in females (OR = 2.943, 95% Confidence Interval = 1.505–5.754). HL was associated with poorer cognitive scores (P < 0.05). “Registration” (P < 0.05) in MMSE was associated with speech- and high-frequency hearing sensitivity. Conclusion The associations between HL and CI varied according to gender in older community-dwellers, suggesting that different mechanisms are involved in the etiology of HL. Moreover, hearing sensitivity was negatively associated with cognition scores; therefore, early screening for HL and CI among older community-dwelling adults is advised.

scholarly journals Gender-specific associations of speech-frequency hearing loss, high-frequency hearing loss, and cognitive impairment among older community dwellers in China

2021 ◽  
Author(s):  
Jingru Wang ◽  
Feng Wang ◽  
Peipei Han ◽  
Yuewen Liu ◽  
Weibo Ma ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Cognitive Impairment ◽  
Confidence Interval ◽  
High Frequency ◽  
Community Dwelling ◽  
World Health ◽  
Early Screening ◽  
High Frequency Hearing Loss ◽  
Hearing Sensitivity ◽  
Community Dwellers

Abstract Background and Aims This study aimed atinvestigating the relationship between speech-frequency hearing loss (SFHL), high-frequency hearing loss (HFHL), and cognitive impairment (CI) and then to determine whether there are any differences in gender among older community dwellers in China. Methods 1012 adults aged ≥ 60 years (428 males; average age, 72.61 ± 5.51 years) and living in Chongming District, Shanghai were enrolled in the study. We used the audiometric definition of hearing loss (HL) adopted by the World Health Organization (WHO). Speech-frequencies were measured at 0.5 kHz, 1 kHz, 2 kHz, and 4 kHz; high-frequencies were measured at 4 kHz and 8 kHz. Pure tone average (PTA) was measured as hearing sensitivity. Cognitive performance was measured using the mini mental state examination (MMSE). Results Our studies demonstrated a 37.6% prevalence of HL in males and a 36.0% prevalence of HL in females. Adjusted for confounding variables, the results from a multivariate analysis showed that SFHL was associated with CI in females (OR = 2.922, 95% Confidence Interval = 1.666–5.124) and males (OR = 2.559, 95% Confidence Interval = 1.252–5.232). However, HFHL was associated with CI only in females (OR = 3.490, 95% Confidence Interval = 1.834–6.643). HL was associated with poorer cognitive scores (P < 0.05). “Registration” (P < 0.05) in MMSE was associated with speech- and high-frequency hearing sensitivity. Conclusions The associations between HL and CI varied according to gender in older community-dwellers, suggesting that different mechanisms are involved in the etiology of HL. Moreover, hearing sensitivity was negatively associated with cognition scores; therefore, early screening for HL and CI among older community-dwelling adults is advised.

scholarly journals Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Yasunori Maeda ◽  
Akira Sasaki ◽  
Shuya Kasai ◽  
Shinichi Goto ◽  
Shin-ya Nishio ◽  
...  
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Genetic Test ◽  
Community Dwelling ◽  
Aminoglycoside Antibiotics ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
High Frequency Hearing Loss ◽  
Study Population ◽  
Hearing Test

AbstractSingle nucleotide polymorphisms in mitochondrial DNA, such as mitochondrial 1555 A>G (m.1555 A>G) and mitochondrial 1494 C>T (m.1494 C>T), are known to be causative mutations of nonsyndromic hearing loss following exposure to aminoglycoside antibiotics. The prevalence of the m.1555 A>G and m.1494 C>T mutations has not been reported for the general population in Japan. The purpose of this study was to investigate the prevalence of m.1555 A>G and m.1494 C>T mutations in a community-dwelling population in Japan in order to prevent aminoglycoside-induced hearing loss. We recruited participants older than 20 years of age to the Iwaki Health Promotion Project in 2014, 2015, and 2016, resulting in the recruitment of 1,683 participants. For each participant, we performed a hearing test and a genetic test for the m.1555 A>G and m.1494 C>T mutations using the TaqMan genotyping method. The m.1555 A>G mutation was detected in only 1 of the 1,683 participants (0.06%). This carrier of the m.1555 A>G mutation was a 69-year-old male with bilateral, symmetric, and high-frequency hearing loss. We provided genetic counseling and distributed a drug card advising him to avoid the administration of aminoglycoside antibiotics. In contrast, the m.1494 C>T mutation was not detected in this study population.

scholarly journals The Relevance of the High Frequency Audiometry in Tinnitus Patients with Normal Hearing in Conventional Pure-Tone Audiometry

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Veronika Vielsmeier ◽  
Astrid Lehner ◽  
Jürgen Strutz ◽  
Thomas Steffens ◽  
Peter M. Kreuzer ◽  
...  
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Normal Hearing ◽  
High Frequency Hearing Loss ◽  
Additional Information ◽  
Tinnitus Severity ◽  
Hearing Thresholds ◽  
High Frequency Audiometry

Objective. The majority of tinnitus patients suffer from hearing loss. But a subgroup of tinnitus patients show normal hearing thresholds in the conventional pure-tone audiometry (125 Hz–8 kHz). Here we explored whether the results of the high frequency audiometry (>8 kHz) provide relevant additional information in tinnitus patients with normal conventional audiometry by comparing those with normal and pathological high frequency audiometry with respect to their demographic and clinical characteristics.Subjects and Methods. From the database of the Tinnitus Clinic at Regensburg we identified 75 patients with normal hearing thresholds in the conventional pure-tone audiometry. We contrasted these patients with normal and pathological high-frequency audiogram and compared them with respect to gender, age, tinnitus severity, pitch, laterality and duration, comorbid symptoms and triggers for tinnitus onset.Results. Patients with pathological high frequency audiometry were significantly older and had higher scores on the tinnitus questionnaires in comparison to patients with normal high frequency audiometry. Furthermore, there was an association of high frequency audiometry with the laterality of tinnitus.Conclusion. In tinnitus patients with normal pure-tone audiometry the high frequency audiometry provides useful additional information. The association between tinnitus laterality and asymmetry of the high frequency audiometry suggests a potential causal role for the high frequency hearing loss in tinnitus etiopathogenesis.

Speech Audibility for Listeners With High-Frequency Hearing Loss

1999 ◽  
Vol 8 (1) ◽  
pp. 47-56 ◽  
Author(s):  
Christopher W. Turner ◽  
Karolyn J. Cummings
Keyword(s):  
Hearing Loss ◽  
Speech Recognition ◽  
High Frequency ◽  
Pure Tone ◽  
Recognition Performance ◽  
Asymptotic Performance ◽  
Profound Hearing Loss ◽  
High Frequency Hearing Loss ◽  
Wide Range ◽  
Speech Information

This study investigated whether there are limitations on the benefit of providing audible speech information to listeners with high-frequency hearing loss. In a group of 10 listeners with various degrees of high-frequency hearing loss, speech recognition was tested across a wide range of presentation levels. For each of these listeners with hearing loss, recognition performance reached an asymptote of <100%. When the spectrum of the speech for this asymptotic performance level was compared with the listener's pure-tone thresholds, it was seen that providing audible speech to high-frequency regions (≥3000 Hz), where hearing loss exceeds 55 dB HL, tended to produce little or no improvement in recognition scores. In contrast, providing audible speech to lower frequency regions for a listener with a flat, severe-to-profound hearing loss did show improvement with increasing speech audibility, despite this listener's thresholds being greater than 55 dB HL. The present study adds further support to the idea that attempting to provide amplification to regions with severe high-frequency hearing loss (≥3000 Hz) may not necessarily benefit many individuals with hearing loss.

scholarly journals The incidence of high-frequency hearing loss after microvascular decompression for trigeminal neuralgia, glossopharyngeal neuralgia, or geniculate neuralgia

2015 ◽  
Vol 123 (6) ◽  
pp. 1500-1506 ◽  
Author(s):  
Parthasarathy Thirumala ◽  
Kristin Meigh ◽  
Navya Dasyam ◽  
Preethi Shankar ◽  
Kanika R. K. Sarma ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Trigeminal Neuralgia ◽  
Microvascular Decompression ◽  
High Frequency ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Contralateral Side ◽  
Glossopharyngeal Neuralgia ◽  
Ipsilateral Side ◽  
High Frequency Hearing Loss

OBJECT The primary aim of this study was to evaluate the incidence and discuss the pathogenesis of high-frequency hearing loss (HFHL) after microvascular decompression (MVD) for trigeminal neuralgia (TGN), glossopharyngeal neuralgia (GPN), or geniculate neuralgia (GN). METHODS The authors analyzed preoperative and postoperative audiogram data and brainstem auditory evoked potentials (BAEPs) from 93 patients with TGN, 6 patients with GPN, and 8 patients with GN who underwent MVD. Differences in pure tone audiometry > 10 dB at frequencies of 0.25, 0.5, 1, 2, 4, and 8 kHz were calculated preoperatively and postoperatively for both the ipsilateral and the contralateral sides. Intraoperative monitoring records were analyzed and compared with the incidence of HFHL, which was defined as a change in pure tone audiometry > 10 dB at frequencies of 4 and 8 kHz. RESULTS The incidence of HFHL was 30.84% on the side ipsilateral to the surgery and 20.56% on the contralateral side. Of the 47 patients with HFHL, 20 had conductive hearing loss, and 2 experienced nonserviceable hearing loss after the surgery. The incidences of HFHL on the ipsilateral side at 4 and 8 kHz were 17.76% and 25.23%, respectively, and 8.41% and 15.89%, respectively, on the contralateral side. As the audiometric frequency increased, the number of patients with hearing loss increased. No significant postoperative difference was found between patients with and without HFHL in intraoperative BAEP waveforms. Sex, age, and affected side were not associated with an increase in the incidence of hearing loss. CONCLUSIONS High-frequency hearing loss occurred after MVD for TGN, GPN, or GN, and the greatest incidence occurred on the ipsilateral side. This hearing loss may be a result of drill-induced noise and/or transient loss of cerebrospinal fluid during the course of the procedure. Changes in intraoperative BAEP waveforms were not useful in predicting HFHL after MVD. Repeated postoperative audiological examinations may be useful in assessing the prognosis of HFHL.

The Sensitivity of Adolescent School-Based Hearing Screens Is Significantly Improved by Adding High Frequencies

2016 ◽  
Vol 32 (6) ◽  
pp. 416-422 ◽  
Author(s):  
Deepa L. Sekhar ◽  
Thomas R. Zalewski ◽  
Jessica S. Beiler ◽  
Beth Czarnecki ◽  
Ashley L. Barr ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Confidence Interval ◽  
Gold Standard ◽  
High Frequency ◽  
State School ◽  
High Frequency Hearing Loss ◽  
High Frequencies ◽  
School Based ◽  
Hazardous Noise ◽  
Sensitivity Specificity

High frequency hearing loss (HFHL), often related to hazardous noise, affects one in six U.S. adolescents. Yet, only 20 states include school-based hearing screens for adolescents. Only six states test multiple high frequencies. Study objectives were to (1) compare the sensitivity of state school-based hearing screens for adolescents to gold standard sound-treated booth testing and (2) consider the effect of adding multiple high frequencies and two-step screening on sensitivity/specificity. Of 134 eleventh-grade participants (2013–2014), 43 of the 134 (32%) did not pass sound-treated booth testing, and 27 of the 43 (63%) had HFHL. Sensitivity/specificity of the most common protocol (1,000, 2,000, 4,000 Hz at 20 dB HL) for these hearing losses was 25.6% (95% confidence interval [CI] = [13.5, 41.2]) and 85.7% (95% CI [76.8, 92.2]), respectively. A protocol including 500, 1,000, 2,000, 4,000, 6,000 Hz at 20 dB HL significantly improved sensitivity to 76.7% (95% CI [61.4, 88.2]), p < .001. Two-step screening maintained specificity (84.6%, 95% CI [75.5, 91.3]). Adolescent school-based hearing screen sensitivity improves with high frequencies.

Marked High-Frequency Hearing Loss in Children: A Problem in Early Identification

1977 ◽  
Vol 42 (3) ◽  
pp. 335-339 ◽  
Author(s):  
Ralph O. Coleman ◽  
Rodney O. Pelson
Keyword(s):  
Hearing Loss ◽  
Young Children ◽  
Hearing Impairment ◽  
Early Identification ◽  
High Frequency ◽  
Pure Tone ◽  
High Frequency Hearing Loss ◽  
Special Analysis ◽  
High Pass

The limitations of noisemakers and speech in detecting marked high-frequency hearing impairment in young children are illustrated by special analysis. The use of high-pass filtering of noisemakers and speech at 6000 Hz and above is recommended as one practical means of identifying losses of this type in children too young for voluntary pure-tone testing.

scholarly journals The Correlation Between Hearing Loss, Especially High-Frequency Hearing Loss and Cognitive Decline Among the Elderly

2021 ◽  
Vol 15 ◽  
Author(s):  
Tongxiang Diao ◽  
Xin Ma ◽  
Junbo Zhang ◽  
Maoli Duan ◽  
Lisheng Yu
Keyword(s):  
Hearing Loss ◽  
Cognitive Function ◽  
Elderly People ◽  
High Frequency ◽  
Pure Tone ◽  
Univariate Analysis ◽  
The Elderly ◽  
High Frequency Hearing Loss ◽  
History Of

Objective: The relation between cognition and hearing loss has been increasingly paid high attention, however, few studies have focused on the role of high-frequency hearing loss in cognitive decline. This study is oriented to role of hearing loss especially high-frequency hearing loss in cognitive impairment among elderly people (age ≥ 60 years).Methods: The Montreal Cognitive Assessment Scale (MoCA) and pure tone audiometry were used to investigate the hearing loss and cognitive function of 201 elderly people older than 60 years. Factors possibly related to cognitive impairment including age, years of education, occupation, living conditions, history of otologic diseases, and high blood pressure were registered. This study consisted of two parts. First, univariate analysis and multiple linear regressions were performed to analyze the possible influencing factors of cognitive function among the 201 elderly people. Second, average hearing thresholds of low frequencies (250, 500 Hz), intermediate frequencies (1 k, 2 kHz), and high frequencies (4 k, 8 kHz) were calculated to screen out 40 cases with high-frequency hearing loss alone and 18 cases with normal hearing. Univariate analysis was used to compare the general condition, cognitive function, and each cognitive domain between the two groups, analyzing the relation between high-frequency hearing loss and cognitive function.Result: We found that age, years of education, pure tone average (PTA), occupation, living condition, history of otologic diseases, years of self-reported hearing loss, and hypertension history were related to cognitive function. Furthermore, age, education experience, duration of self-reported hearing loss, and hypertension were independent factors (p &lt; 0.05). PTA was negatively related with attention, orientation, and general cognition (p &lt; 0.05). There were only 18 cases (9.0%) with normal hearing, and 40 cases (19.9%) with abnormal high-frequency hearing alone. The overall cognitive function showed no significant difference between them (p &gt; 0.05); in contrast, the speech and abstract ability were significantly decreased in cases with high-frequency hearing loss (p &lt; 0.05).Conclusion: The increase of PTA among the elderly may affect the overall cognition by reducing attention and orientation. High-frequency hearing loss alone can affect the language and abstract ability to a certain extent, which is worthy of more attention.

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