Multidrug Therapy and Eye Disease in Leprosy: A Cross-Sectional Study in the People's Republic of China

1994 ◽  
Vol 23 (4) ◽  
pp. 835-842 ◽  
Author(s):  
PAUL COURTRIGHT ◽  
LU-FANG HU ◽  
HUAN-YING LI ◽  
SUSAN LEWALLEN
1990 ◽  
Vol 30 (4) ◽  
pp. 239-259 ◽  
Author(s):  
Shusheng Zhai ◽  
Renate D. Kimbrough ◽  
Bo Meng ◽  
Jingyuan Han ◽  
Maurice LeVois ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258233
Author(s):  
Kofi Asiedu ◽  
Samuel Kyei ◽  
Madison Adanusa ◽  
Richard Kobina Dadzie Ephraim ◽  
Stephen Animful ◽  
...  

The study determined the frequency of dry eye, its clinical subtypes and risk factors among pregnant women. This study was a hospital-based cross-sectional study of pregnant women visiting the antenatal clinic of the University of Cape Coast hospital. Clinical dry eye tests were performed along with the administration of a symptom questionnaire. Frequencies, chi-square analysis and logistic regression analyses were conducted to determine the frequency of dry eye disease, its clinical subtypes and associated factors. The prevalence of dry eye disease among the cohort of pregnant women was 82/201 (40.8% 95% confidence interval 34.3%-47.3%). Among the 82 pregnant women with dry eye disease, the frequencies of the clinical subtypes of dry eye were: evaporative dry eye [15/82(18.3%; 95% CI, 12.2%–25.2%)], aqueous deficient dry eye [10/82(12.2.%; 95% CI, 7.3%–18.3)], mixed dry eye [6/82(7.3%; 95% CI, 3.7%–11.0%)], and unclassified dry eye [51/82(62.2%; 95% CI, 52.4%–72.0%)]. Binary logistic regression analysis showed that the following factors were not significantly associated with dry eye: age, BMI, lipid profile, prolactin level, testosterone level, ocular protection index and blink rate. Only gestational age was significantly associated with dry eye disease in pregnancy. In conclusion, the current study showed that dry eye disease occurs frequently in pregnant women ranging from the first to the third trimester and it is associated with increasing gestational age. The evaporative dry eye was more common compared to the aqueous deficient dry eye, but most dry eye could not be classified.


Author(s):  
Marcos Túlio Raposo ◽  
Ana Virgínia de Queiroz Caminha ◽  
Jorg Heukelbach ◽  
Miguel Ángel Sánchez-González ◽  
Jovany Luis Alves de Medeiros ◽  
...  

This cross-sectional study assessed the grade of physical impairments in 61 individuals with leprosy receiving multidrug therapy (MDT) under the Brazilian Unified Health System (SUS), and residing in Campina Grande, Paraíba State, Brazil. Impairments were assessed using the disability grade (DG) standardized by the WHO, and the EHF score (Eye-Hand-Foot sum of impairment scores). Impairments were detected in 25 (41%) of the subjects. A total of 14 (23%) patients scored DG 1, while 11 (18%) were assigned DG 2. The EHF score ranged from 1 to 10 points in the group of patients with physical impairments, with a mean score of 3.6 points. The majority of individuals with impairments were affected in at least two sites. We conclude that the EHF score showed overlapping impairments in the segments examined and may be more appropriate than the DG classification system for describing the degree of physical impairment of leprosy patients.


BMJ ◽  
1998 ◽  
Vol 316 (7145) ◽  
pp. 1643-1646 ◽  
Author(s):  
A Reidy ◽  
D C Minassian ◽  
G Vafidis ◽  
J Joseph ◽  
S Farrow ◽  
...  

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