Comparison of Solid-Phase Extraction and Micro-Solid-Phase Extraction for Liquid Chromatography/Mass Spectrometry Analysis of Pesticides in Water Samples
2003 ◽
Vol 86
(5)
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pp. 941-946
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Keyword(s):
Ion Trap
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Abstract Our recent on-line solid-phase extraction (SPE) device for micro-liquid chromatography, known as micro-solid-phase extraction (μSPE), was compared with traditional SPE for the analysis, from aqueous samples, of 4 pesticides belonging to different classes. Two different kinds of adsorbents, C18 and graphitized carbon black, were tested. A 2-stage ion trap mass spectrometer, equipped with homemade microflow electrospray ion (ESI) source, was used. Detection limits with a signal-to-noise ratio of 3:1 for both extraction methods were in the range of 0.1 μg/L for all compounds. However, better recoveries were obtained when μSPE traps were used.