scholarly journals 178 Efficacy of commercial products on growth performance of nursery pigs fed diets with fumonisin-contaminated corn

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 78-79
Author(s):  
Zhong-Xing Rao ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  

Abstract Two experiments were conducted to determine the efficacy of commercial products on growth performance of nursery pigs fed high fumonisin diets. In Exp. 1,350 pigs (241 × 600; DNA; initially 9.9 kg) were used with 5 pigs per pen and 14 pens per treatment. Five dietary treatments consisted of a positive control (low fumonisin, 4 ppm fumonisin; FB1 + FB2), negative control (50 ppm fumonisin;) and the negative control with one of three products (0.3% of Kallsil Dry, Kemin Industries Inc., Des Moines, IA; 0.3% of Feed Aid Wide Spectrum, NutriQuest, Mason City, IA; 0.17% of Biofix Select Pro, Biomin America Inc., Overland Park, KS). Diets were fed for 14 d. Pens were assigned to treatments in a randomized complete block design with initial weight as the blocking factor. Data were analyzed using nlme package in R program (version 3.5.2) with pen as experimental unit. Pigs fed the negative control, or diets with Kallsil Dry or Feed Aid had decreased (P< 0.05) ADG, ADFI, and G:F compared with those fed the positive control and diet with Biofix. Pigs fed the positive control diet had decreased (P< 0.05) d 14 serum sphinganine to sphingosine (Sa:So) ratio than those fed other diets. In Exp. 2, 300 pigs (241 × 600; initially 10.4 kg) were used and fed experimental diets for 28 d. Procedures were similar to Exp. 1 except there were 12 replicates per treatment and diets contained 30 ppm fumonisin. Pigs fed the negative control, or diets with Kallsil Dry or Feed Aid had decreased (P< 0.05) ADG and G:F, and greater (P< 0.05) d 14 and 28 Sa:So ratios compared with the positive control and diet with Biofix. In summary, adding Biofix to high fumonisin diets mitigated the negative effects of fumonisin while Kallsil Dry and Feed Aid did not.

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Zhong-Xing Rao ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  

Abstract Two experiments were conducted to determine the efficacy of various commercial products on growth performance of nursery pigs fed diets high in fumonisin. In experiment 1, 350 pigs (241 × 600; DNA, Columbus, NE; initially 9.9 kg) were used with five pigs per pen and 14 replicates per treatment. After weaning, pigs were fed common diets for 21 d before the experiment started. The five dietary treatments consisted of a positive control (low fumonisin), a negative control (60 mg/kg of fumonisin B1 + B2 in complete diet), and the negative control with one of three products (0.3% of Kallsil Dry, Kemin Industries Inc., Des Moines, IA; 0.3% of Feed Aid Wide Spectrum, NutriQuest, Mason City, IA; 0.17% of Biofix Select Pro, Biomin America Inc., Overland Park, KS). Diets were fed in mash form for 14 d and followed with a low fumonisin diet for 13 d. For the 14-d treatment period, pigs fed the positive control diet and Biofix Select Pro had greater (P < 0.05) average daily gain (ADG), average daily feed intake (ADFI), and gain:feed (G:F) compared to those fed the high fumonisin negative control, or high fumonisin diets with Kallsil Dry or Feed Aid Wide Spectrum. Serum sphinganine to sphingosine ratios (SA:SO) were greater (P < 0.05) in all pigs fed high fumonisin diets compared to the positive control. In experiment 2, 300 pigs (241 × 600; DNA; initially 10.4 kg) were used. Procedures were similar to experiment 1 except there were 12 replicate pens per treatment, high fumonisin diets contained 30 mg/kg fumonisin, and experimental diets were fed for 28 d. Similar to experiment 1, pigs fed the positive control diet and treatment with Biofix Select Pro had greater (P < 0.05) ADG and G:F, and lower (P < 0.05) serum SA:SO compared to pigs fed the high fumonisin negative control, or high fumonisin diets with Kallsil Dry or Feed Aid Wide Spectrum. In summary, pigs fed diets containing 60 mg/kg of fumonisin for 14 d or 30 mg/kg of fumonisin for 28 d had poorer ADG and G:F and greater serum SA:SO compared to pigs fed a diet with less than 5 mg/kg of fumonisin. Adding Biofix Select Pro to diets appeared to mitigate the negative effects of high fumonisin concentrations, while Kallsil Dry and Feed Aid Wide Spectrum did not.


2019 ◽  
Vol 97 (9) ◽  
pp. 3907-3919 ◽  
Author(s):  
Hang Lu ◽  
Imke Kühn ◽  
Mike R Bedford ◽  
Hayley Whitfield ◽  
Charles Brearley ◽  
...  

Abstract The objective of this present study was to determine the effects of phytase dosing on growth performance, mineral digestibility, phytate breakdown, and the level of glucose transporter type 4 (GLUT4) in muscle plasma membranes of weanling pigs. A total of 160 barrows were used in a randomized completely block design and assigned to 4 treatments for a 7-wk study. Depending on the feeding phase, diets differed in dietary calcium (Ca) and phosphorus (P) levels (positive control [PC]: 8 to 6.8g/kg Ca; 7.3 to 6.3 g/kg P; negative control [NC]: 5.5 to 5.2 g/kg Ca; 5.4 to 4.7 g/kg P). NC diets were supplemented with phytase at 0 (NC); 500 (NC + 500 FTU); or 2,000 FTU/kg (NC + 2,000 FTU) phytase units/kg. Blood was collected after fasting (day 48) or feeding (day 49) for measurement of plasma inositol concentrations. On day 49, 2 pigs per pen were euthanized, and duodenal and ileal digesta samples were collected to determine inositol phosphates (InsP6-2) concentrations. High phytase supplementation increased BW on days 21, 35, and 49 (P < 0.05). Over the entire feeding period, ADG, ADFI, and feed efficiency were increased by NC + 2,000 FTU compared with the other treatments (P < 0.05). Postprandial plasma inositol concentration was increased in NC + 2,000 (P < 0.01), but there was only a tendency (P = 0.06) of a higher fasting plasma inositol concentration in this group. Inositol concentrations in the portal vein plasma (day 49) were not different among treatments. Duodenal digesta InsP5 and InsP6 concentrations were similar in PC and NC, but higher in these 2 treatments (P < 0.05) than those supplemented with phytase. Phytase supplementation decreased InsP6-4, resulting in increased InsP3-2 and myo-inositol concentrations. Similar effects were found in ileal contents. Compared with NC, phytase supplementation resulted in greater cumulative InsP6-2 disappearance (93.6% vs. 72.8% vs. 25.0%, for NC + 2,000 FTU, NC + 500 FTU and NC, respectively, P < 0.01) till the distal ileum. Longissimus dorsi muscle plasma membrane GLUT4 concentration was increased by NC + 2,000 FTU (P < 0.01) compared with NC. In summary, high phytase supplementation increased growth performance of nursery pigs. The higher myo-inositol release from phytate could contribute to the increased expression of GLUT4 in muscle plasma membranes. Further investigation is needed to determine whether this is associated with enhanced cellular glucose uptake and utilization.


2019 ◽  
Vol 98 (1) ◽  
Author(s):  
Gloria A Casas ◽  
Laia Blavi ◽  
Tzu-Wen L Cross ◽  
Anne H Lee ◽  
Kelly S Swanson ◽  
...  

Abstract An experiment was conducted to test the hypothesis that inclusion of the direct fed microbial Clostridium butyricum in diets for weanling pigs will improve growth performance, systemic immune function, microbiota composition, and gut morphology in weaned pigs. A total of 275 newly weaned pigs (20 ± 2 d of age) with an average initial BW of 6.4 ± 0.8 kg were allotted to a randomized complete block design with 11 pens per treatment. Diets included a positive control diet containing Carbadox, a negative control diet without Carbadox, and three treatment diets in which 1,250 × 108 cfu/kg, 2,500 × 108 cfu/kg, or 3,500 × 108 cfu/kg of C. butyricum was added to the negative control diet. A two-phase feeding program was used (phase 1, 14 d; phase 2, 21 d). At the conclusion of the experiment (day 35), a blood sample was collected from one pig per pen (11 pigs per treatment) and this pig was then euthanized and digesta and tissues samples were collected. Results indicated that for the overall phase, pigs fed the positive control diet had greater (P &lt; 0.05) ADG and ADFI and tended (P = 0.064) to have greater final BW than pigs fed the negative control diet. The ADG and G:F increased and then decreased as increasing doses of C. butyricum were included in the diet (quadratic, P &lt; 0.05). The concentration of tumor necrosis factor-α was less (P &lt; 0.05) in pigs fed the positive control diet compared with pigs fed the negative control diet or diets containing C. butyricum. Crypt depth tended (P = 0.08) to be less in pigs fed the negative control diet compared with pigs fed the positive control diet and villus height tended to increase as the doses of C. butyricum increased in the diets (quadratic, P = 0.08). Villus height also tended (P = 0.084) to be greater in pigs fed diets containing C. butyricum compared with pigs fed the positive control diet. Crypt depth increased as the dose of C. butyricum increased (quadratic, P &lt; 0.05) and villus width at the bottom tended to increase (linear, P = 0.072) as the dose of C. butyricum increased in the diet. Alpha and beta diversity indices of ileal and colonic microbiota were not affected by diet. In conclusion, addition of 1,250 × 108 cfu/kg of C. butyricum, but not greater levels, to diets fed to weanling pigs increased growth performance and tended to increase villus height and crypt depth, but changes in the abundance of intestinal microbiota were not observed.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 43-43
Author(s):  
Madison R Wensley ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  

Abstract A total of 320 barrows (DNA 200×400, initially 11.3 ± 0.65 kg BW) were used in a 21-d growth trial evaluating the effects of feeding Trp biomass (CJ America-Bio, Downers Grove, IL) as a source of Trp on nursery pig performance. Pigs were weaned at approximately 21 d of age, placed in pens based on initial BW, and fed a common diet. On d 21 after weaning, pigs were weighed and pens were allotted to 1 of 4 dietary treatments with 5 pigs/pen and 16 replicates/treatment. Dietary treatments included a negative control (16% SID Trp:Lys), positive control (21% SID Trp:Lys from crystalline L-Trp), or diets containing Trp biomass to provide 21 or 23.5% SID Trp:Lys (included at 0.104 or 0.156% of the diet, respectively). Diets were corn-soybean meal based and contained 1.25% SID Lys with other AA set to meet or exceed NRC (2012) requirement estimates. The Trp biomass contained 69% Trp. Growth data were analyzed as a randomized complete block design using PROC GLIMMIX of SAS with pen as the experimental unit. Overall (d 0 to 21) pigs fed 21% Trp from L-Trp or Trp biomass had increased (P < 0.05) ADG compared to the control, with pigs fed the 23.5% SID Trp biomass intermediate. Pigs fed the 21% Trp from Trp biomass had improved (P < 0.05) G:F compared to the control with others intermediate. In conclusion, Trp biomass is a viable alternative to crystalline Trp, but further evaluation at higher inclusion levels is needed.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 85-86
Author(s):  
Dalton Humphrey ◽  
Spenser Becker ◽  
Jason Lee ◽  
Keith Haydon ◽  
Laura L Greiner

Abstract Four hundred and eighty (PIC 337 X 1050, PIC Genus, Hendersonville, TN) pigs were used to evaluate a novel threonine source (ThrPro, CJ America-Bio, Fort Dodge, IA) for nursery pigs from approximately 7 kg to 20 kg. At weaning, pigs were sorted by gender and fed a common diet for one week. Upon completion of the first week, pigs were sorted into randomized complete blocks, equalized by weight, within 16 replications. Pigs were allocated to one of three dietary treatments: positive control (POS)-SID LYS:THR 0.60, negative control (NEG)-SID LYS:THR ≤0.46 and alternative threonine source (TEST)-SID LYS:THR 0.60. All other nutrients met or exceeded the NRC (2012) recommendations. Growth and intake data were analyzed using PROC MIXED procedure in SAS. The experimental unit was the pen. During the first 14 days, pigs fed TEST had similar ADG (0.417 vs. 0.414 kg/d, P=0.81) and G:F (0.977 vs. 1.030, P=0.18) compared to POS, and increased ADG (0.417 vs. 0.387 kg/d, P=0.01) and G:F (0.977 vs. 0.898, P=0.05) compared to NEG. Over days 14-28, pigs fed TEST had similar ADG (0.523 vs. 0.532 kg/d, P=0.49) and G:F (0.712 vs. 0.707, P=0.71) compared to POS, and increased ADG (0.523 vs. 0.479 kg/d, P=0.002) and G:F (0.712 vs. 0.627, P&lt; 0.0001) compared to NEG. Overall (d 0 to 28), pigs fed TEST had similar ADG (0.466 vs. 0.474 kg/d, P=0.48) and G:F (0.808 vs. 0.816, P=0.55) compared to POS, and increased ADG (0.466 vs. 0.433 kg/d, P=0.002) and G:F (0.808 vs. 0.725, P&lt; 0.0001) compared to NEG. ADFI was not significantly different across treatments for the entirety of the study. In conclusion, the replacement of L-threonine with a novel threonine source resulted in similar growth performance in nursery pigs from approximately 7 kg to 20 kg.


2020 ◽  
Vol 42 ◽  
pp. e50436
Author(s):  
Elvania Maria da Silva Costa Moreira ◽  
Leilane Rocha Barros Dourado ◽  
Hidaliana Paumerik Aguiar Bastos ◽  
Mabell Nery Ribeiro ◽  
Sandra Regina Gomes da Silva ◽  
...  

The objective of this study was to evaluate the inclusion of protease and sugarcane yeast in poultry diets on performance, organ weight, intestinal biometry, chemical composition and deposition of body nutrients in the 1 to 7-day old phase. The experimental design consisted of a randomized complete block design, in a factorial arrangement of 2 (without and with the enzyme protease) x3 (yeast levels: 0, 6 and 12%) +1 (positive control diet), totaling seven treatments with five replicates, birds per experimental unit. The treatments used consisted of a positive control diet and the others were the negative control, with reductions in nutritional levels of protein and amino acids by 4% requirement. In the negative control diets, protease enzyme was included in three levels of sugarcane yeast. In isolation, treatments with or without inclusion of protease influenced the chemical composition of the birds. The levels of yeast from sugarcane yeast presented effects for weight gain, feed conversion, moisture and crude protein in the nutrient deposition. The inclusion of protease in diets for broiler chicks cannot remedy the poor performance provided by the use of sugarcane yeast, in addition to presenting lower levels of deposition of body nutrients.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 87-87
Author(s):  
Payton L Dahmer ◽  
Cassandra K Jones

Abstract A total of 360 weanling pigs (DNA 200 x 400; initially 9.7 ± 0.23 kg BW) were used in a 21-d growth trial to evaluate the effects of commercial diet acidifiers in nursery diets. Upon weaning, pigs were weighed and allotted to pens (6 pigs/pen, 10 replicate pens/treatment, blocked by 2 separate nursery rooms) and pens were then randomly assigned to one of 6 treatment diets: 1) negative control (no antibiotics or acidifiers) and the control with 2) 0.25% Acidifier A (KEM-GEST™, Kemin Industries, Des Moines, IA); 3) 0.3% Acidifier B (ACITVATE® DA, Novus International, Saint Charles, MO); 4) 0.5% Acidifier C (OutPace®, PMI Additives, Arden Hills, MN); 5) 50 g/ton carbadox; 6) 400 g/ton chlortetracycline. Pigs were fed common phase 1 and phase 2 starter diets without antimicrobials for 21 days, then fed experimental diets for 21 days. Data were analyzed as a completely randomized block design with pen as the experimental unit. Dietary treatment significantly impacted (P &lt; 0.05) all growth response criteria for each week of the experiment. Overall (d 0 to 21), ADG was the greatest (P &lt; 0.0001) for pigs fed a diet containing CTC. Likewise, ADFI was increased (P &lt; 0.0001) for pigs consuming CTC compared to those fed the negative control, acidifier A, acidifier B and carbadox diets, while those fed acidifier C were intermediate. Feed efficiency was poorest (P &lt; 0.0001) in pigs fed a diet with carbadox. By the end of the experiment, pigs fed CTC were significantly heavier (P &lt; 0.0001) than pigs fed all remaining treatments. In summary, feeding CTC improved nursery pig performance while carbadox unexpectedly reduced it. The addition of dietary acidifiers did not improve growth performance compared to a negative control.


Author(s):  
S. Gilani ◽  
M.I. Garcia ◽  
L. Barnard ◽  
Y. Dersjant-Li ◽  
C. Millán ◽  
...  

The following study evaluated effects of a xylanase and beta-glucanase combination on growth performance of broilers fed energy reduced versus nutritionally adequate maize-soybean meal-based diets. A total of 648, one-day-old male broilers (Ross 308) were assigned to floor-pens (24 birds/pen, nine pens/treatment, three treatments) in a randomised block design. Treatments included: (1) a nutritionally adequate positive control diet (PC); (2) a negative control (NC) diet in which energy, crude protein and digestible amino acids were reduced by 3.4% (-105 kcal apparent metabolisable energy), 2.3% and 1.2 to 3.0% vs PC, respectively; and (3) NC plus a xylanase and beta-glucanase combination that supplied 1,220 U xylanase and 152 U beta-glucanase per kilogram of final feed. All diets contained a background of 500 FTU/kg phytase and were offered to birds ad libitum. Birds fed NC showed reduced average daily gain (ADG) by -6.1% (P<0.05); increased feed conversion ratio (FCR) by 9.2 points (P<0.05), and overall (d 1-35) body weight corrected FCR which was increased by 9.4 points (P<0.05) vs the PC group. Enzyme supplementation increased final BW (+4.2%, P<0.05), ADG (+5.4%, P<0.05) and tended to reduce FCR (+7.5 points, P=0.054) from d 22-35 vs NC, without affecting average daily feed intake. Improvements in performance due to the enzyme combination were equivalent to performance on the PC diet in all cases. The results suggested that significant improvements in growth performance of broilers fed maize-soybean meal-based diets which had been reduced in energy and nutrients can be realised by supplementation with xylanase in combination with beta-glucanase.


2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Dalton Humphrey ◽  
Spenser Becker ◽  
Jason Lee ◽  
Keith Haydon ◽  
Laura Greiner

Abstract Four hundred and eighty (PIC 337 X 1050, PIC Genus, Hendersonville, TN) pigs were used to evaluate a novel threonine source (ThrPro, CJ America Bio, Fort Dodge, IA) for nursery pigs from approximately 7 to 20 kg body weight (BW). After weaning, pigs were sorted by sex and fed a common diet for 1 wk. Upon completion of the first week, pigs were sorted into randomized complete blocks, equalized by weight, within 16 replications. Pigs were allocated to one of three dietary treatments: positive control (POS)—standard ileal digestible threonine-to-lysine ratio (SID; Thr:Lys) 0.60, negative control (NEG)—SID Thr:Lys ≤0.46, and alternative Thr source (TEST)—SID Thr:Lys 0.60. The alternative Thr source included fermentative biomass and was assumed to contain 75% Thr and a digestibility coefficient of 100% based on the manufacturer’s specifications. All other nutrients met or exceeded the NRC recommendations. Growth and intake data were analyzed as repeated measures with a compound symmetry covariance structure using the MIXED procedure in SAS 9.4 (SAS Institute Inc., Cary, NC) with pen as the experimental unit. Treatment, phase, the interaction between treatment and phase, and block were included as fixed effects in the model. Differences in total removals were tested using Fisher’s Exact Test of PROC FREQ. Results were considered significant at P ≤ 0.05 and considered a trend at P &gt; 0.05 and P ≤ 0.10. During the first 14 d, pigs fed TEST had decreased gain-to-feed ratio (G:F; 0.77 vs. 0.80, P = 0.022) compared to POS and increased G:F (0.77 vs. 0.73, P &lt; 0.001) compared to NEG. Over days 14–28, pigs fed TEST had similar G:F (0.71 vs. 0.70, P = 0.112) compared to POS and increased G:F (0.71 vs. 0.63, P &lt; 0.001) compared to NEG. Overall (days 0–28), pigs fed TEST had similar average daily gain (ADG; 0.47 vs. 0.47 kg/d, P = 0.982) and G:F (0.76 vs. 0.74, P = 0.395) compared to POS and increased ADG (0.47 vs. 0.43 kg/d, P &lt; 0.001) and G:F (0.76 vs. 0.67, P &lt; 0.001) compared to NEG. The average daily feed intake was not significantly different across treatments for the entirety of the study. In conclusion, the replacement of crystalline L-Thr with a novel Thr source resulted in similar growth performance in nursery pigs from approximately 7 to 20 kg.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 61-62
Author(s):  
Woongbi Bi Kwon ◽  
Jose A Soto ◽  
Hans H Stein

Abstract An experiment was conducted to test the hypothesis that addition of Val, Ile, or Trp alone or in combination will reduce the negative effects of excess Leu in diets for growing pigs. A total of 288 growing pigs (28.6 ± 2.5 kg) were randomly assigned to 1 of 9 dietary treatments in a randomized complete block design. There were 2 barrows and 2 gilts in each pen and 8 replicate pens per treatment. A control diet based on corn and soybean meal and 8 diets based on corn and a high-protein corn product (48% crude protein) with 2 levels of crystalline L-Val (0 or 0.10%), L-Ile (0 or 0.10%), and L-Trp (0 or 0.05%) were formulated. The crystalline L-Val, L-Ile, and L-Trp increased standardized ileal digestible (SID) Val:Lys from 70 to 80%, SID Ile:Lys from 53 to 63%, and SID Trp:Lys from 18 to 23%, respectively. All diets were formulated to contain 1.00% SID Lys and the 8 diets containing corn protein contained 171% SID Leu:Lys. Individual pig weights were recorded at the beginning and at the conclusion of the 28-d experiment. Data were analyzed using the PROC MIXED of SAS with a pen as the experimental unit. Diet was the fixed effect and block and replicate within block were random effects. Results indicated that final body weight and average daily gain were not different between pigs fed the control diet and pigs fed the diet with Val and Trp addition, but greater (P &lt; 0.001) than for pigs fed the diet with Val addition, Ile addition, Trp addition, Val and Ile addition, Ile and Trp addition, or Val, Ile, and Trp addition (Table 1). In conclusion, addition of Val and Trp to diets with excess Leu may prevent negative effects of excess Leu in diets for growing pigs.


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