185 The Impacts of Commercial Dietary Acidifiers on Growth Performance of Nursery Pigs

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 87-87
Author(s):  
Payton L Dahmer ◽  
Cassandra K Jones

Abstract A total of 360 weanling pigs (DNA 200 x 400; initially 9.7 ± 0.23 kg BW) were used in a 21-d growth trial to evaluate the effects of commercial diet acidifiers in nursery diets. Upon weaning, pigs were weighed and allotted to pens (6 pigs/pen, 10 replicate pens/treatment, blocked by 2 separate nursery rooms) and pens were then randomly assigned to one of 6 treatment diets: 1) negative control (no antibiotics or acidifiers) and the control with 2) 0.25% Acidifier A (KEM-GEST™, Kemin Industries, Des Moines, IA); 3) 0.3% Acidifier B (ACITVATE® DA, Novus International, Saint Charles, MO); 4) 0.5% Acidifier C (OutPace®, PMI Additives, Arden Hills, MN); 5) 50 g/ton carbadox; 6) 400 g/ton chlortetracycline. Pigs were fed common phase 1 and phase 2 starter diets without antimicrobials for 21 days, then fed experimental diets for 21 days. Data were analyzed as a completely randomized block design with pen as the experimental unit. Dietary treatment significantly impacted (P < 0.05) all growth response criteria for each week of the experiment. Overall (d 0 to 21), ADG was the greatest (P < 0.0001) for pigs fed a diet containing CTC. Likewise, ADFI was increased (P < 0.0001) for pigs consuming CTC compared to those fed the negative control, acidifier A, acidifier B and carbadox diets, while those fed acidifier C were intermediate. Feed efficiency was poorest (P < 0.0001) in pigs fed a diet with carbadox. By the end of the experiment, pigs fed CTC were significantly heavier (P < 0.0001) than pigs fed all remaining treatments. In summary, feeding CTC improved nursery pig performance while carbadox unexpectedly reduced it. The addition of dietary acidifiers did not improve growth performance compared to a negative control.

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 208-208
Author(s):  
Afton Sawyer ◽  
Scott Carter ◽  
Carson Cooper ◽  
Pornpim Aparachita ◽  
Megan R Bible ◽  
...  

Abstract One-hundred forty weanling pigs (5.26 kg; 20 d of age) were used to determine the effects of a nutritional water supplement (WB; Water Boost, Furst-McNess, Freeport, IL) on growth performance of nursery pigs. Pigs were randomly allotted to two water treatments (7 pens/treatment; 10 pigs/pen). The water treatments were 0 and 62.5 mL WB/L of water (stock solution) supplied by water medicators (1:100 dilution). Pigs were fed simple, corn soybean meal diets (no plasma or crystalline lactose utilized) in four dietary phases (Phase 1: d 0-7, Phase 2: d 7-14, Phase 3: d 14-21, and Phase 4: d 21-42). The water treatments were provided on d 0 through d 3. Pigs and feeders were weighed weekly to determine ADG, ADFI, and G:F. Water meters were used to record and calculate water disappearance. Data were analyzed as a randomized complete block design with pen serving as the experimental unit. Water disappearance (L/pig/d) was not affected from d 0-21, but it increased (P < 0.01) for pigs provided WB for d 21-42 (1.71 vs 2.12) and d 0-42 (1.11 vs 1.35). Growth performance was not affected by WB during d 0-21. However, from d 21-42, WB tended to increase (P < 0.10) ADG (483 vs 528 g/d) and ADFI (706 vs 767 g/d), but it had no effect on G:F. For the overall period, pigs provided WB from d 0-3 tended to have improved G:F (0.671 vs 0.684) and numerical increases in ADG (P = 0.14) and ADFI (P = 0.17) were observed. Final ending body weight tended to be increased (P < 0.10) for pigs provided WB (18.6 vs 19.9 kg). These results suggest providing WB for the first three days in the nursery to pigs fed corn soybean meal-based diets increased water disappearance and tended to improve growth performance of nursery pigs.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 43-43
Author(s):  
Madison R Wensley ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
Steve S Dritz ◽  
Mike D Tokach ◽  
...  

Abstract A total of 320 barrows (DNA 200×400, initially 11.3 ± 0.65 kg BW) were used in a 21-d growth trial evaluating the effects of feeding Trp biomass (CJ America-Bio, Downers Grove, IL) as a source of Trp on nursery pig performance. Pigs were weaned at approximately 21 d of age, placed in pens based on initial BW, and fed a common diet. On d 21 after weaning, pigs were weighed and pens were allotted to 1 of 4 dietary treatments with 5 pigs/pen and 16 replicates/treatment. Dietary treatments included a negative control (16% SID Trp:Lys), positive control (21% SID Trp:Lys from crystalline L-Trp), or diets containing Trp biomass to provide 21 or 23.5% SID Trp:Lys (included at 0.104 or 0.156% of the diet, respectively). Diets were corn-soybean meal based and contained 1.25% SID Lys with other AA set to meet or exceed NRC (2012) requirement estimates. The Trp biomass contained 69% Trp. Growth data were analyzed as a randomized complete block design using PROC GLIMMIX of SAS with pen as the experimental unit. Overall (d 0 to 21) pigs fed 21% Trp from L-Trp or Trp biomass had increased (P < 0.05) ADG compared to the control, with pigs fed the 23.5% SID Trp biomass intermediate. Pigs fed the 21% Trp from Trp biomass had improved (P < 0.05) G:F compared to the control with others intermediate. In conclusion, Trp biomass is a viable alternative to crystalline Trp, but further evaluation at higher inclusion levels is needed.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 78-79
Author(s):  
Zhong-Xing Rao ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  

Abstract Two experiments were conducted to determine the efficacy of commercial products on growth performance of nursery pigs fed high fumonisin diets. In Exp. 1,350 pigs (241 × 600; DNA; initially 9.9 kg) were used with 5 pigs per pen and 14 pens per treatment. Five dietary treatments consisted of a positive control (low fumonisin, 4 ppm fumonisin; FB1 + FB2), negative control (50 ppm fumonisin;) and the negative control with one of three products (0.3% of Kallsil Dry, Kemin Industries Inc., Des Moines, IA; 0.3% of Feed Aid Wide Spectrum, NutriQuest, Mason City, IA; 0.17% of Biofix Select Pro, Biomin America Inc., Overland Park, KS). Diets were fed for 14 d. Pens were assigned to treatments in a randomized complete block design with initial weight as the blocking factor. Data were analyzed using nlme package in R program (version 3.5.2) with pen as experimental unit. Pigs fed the negative control, or diets with Kallsil Dry or Feed Aid had decreased (P&lt; 0.05) ADG, ADFI, and G:F compared with those fed the positive control and diet with Biofix. Pigs fed the positive control diet had decreased (P&lt; 0.05) d 14 serum sphinganine to sphingosine (Sa:So) ratio than those fed other diets. In Exp. 2, 300 pigs (241 × 600; initially 10.4 kg) were used and fed experimental diets for 28 d. Procedures were similar to Exp. 1 except there were 12 replicates per treatment and diets contained 30 ppm fumonisin. Pigs fed the negative control, or diets with Kallsil Dry or Feed Aid had decreased (P&lt; 0.05) ADG and G:F, and greater (P&lt; 0.05) d 14 and 28 Sa:So ratios compared with the positive control and diet with Biofix. In summary, adding Biofix to high fumonisin diets mitigated the negative effects of fumonisin while Kallsil Dry and Feed Aid did not.


Author(s):  
Payton L Dahmer ◽  
Cassandra K Jones

Abstract A total of 360 weanling pigs (DNA 200 × 400; initially 9.7 ± 0.23 kg BW) were used in a 21-d experiment with 6 pigs/pen, 10 replicate pens/treatment, and 2 separate nursery rooms, each with 30 pens. Pigs were weighed and allotted to pens based on BW in a completely randomized block design to one of 6 treatment diets: 1) Negative control (no organic acids or antibiotics) and the control with 2) 0.25% Acidifier A; 3) 0.3% Acidifier B; 4) 0.5% Acidifier C); 5) 50 g/t Carbadox; 6) 400 g/t Chlortetracycline. Upon weaning, a common diet with no antibiotics or additives was fed for 21 d (phases 1 and 2; d -21 to d 0), followed by a 21 d experimental period (phase 3; d 0 to d 21) where treatment diets were fed. Pigs and feeders were individually weighed on a weekly basis to calculate average daily gain (ADG), average daily feed intake (ADFI) and feed efficiency (G:F). Data were analyzed using the PROC GLIMMIX procedure of SAS (v 9.4, SAS Inst., Cary, NC) with pen as the experimental unit, treatment as a fixed effect and room as a random effect. Dietary treatment had a significant impact (P &lt; 0.05) on ADG, ADFI and G:F each week and for the overall experimental period (d 0 to 21). Specifically, from d 0 to 7, pigs fed CTC had increased (P = 0.001) ADG compared to those fed Acidifier B, Acidifier C and Carbadox, while pigs fed the negative control and Acidifier A diets were intermediate. Additionally, pigs fed the CTC diet had improved (P = 0.0002) ADFI when compared to all other treatments. From d 7 to 14 and d 14 to 21, pigs fed the Carbadox diet had decreased (P &lt; 0.0001) ADG compared to all other treatments. During the overall period (d 0 to 21), pigs fed diets containing Carbadox had reduced ADG and ADFI (P &lt; 0.0001), while pigs fed CTC had improved (P &lt; 0.0001) ADG compared to all other treatments. Additionally, blood parameters, fecal consistency and fecal microbial populations were analyzed on a subset of pigs (n = 5 pigs/treatment). Dietary treatment significantly impacted (P &lt; 0.05) concentrations of protein, globulin, phosphorus, alkaline phosphatase, and sorbitol dehydrogenase in the blood. Treatment also significantly impacted (P = 0.0005) fecal score but did not affect (P = 0.59) fecal microbial growth from d 0 to 21. In summary, CTC continues to be a valuable additive to improve performance in the nursery. Further investigation surrounding the efficacy of dietary acidifiers as antibiotic alternatives is warranted given inconclusive evidence in this study.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 191-192
Author(s):  
Jorge Y Perez-Palencia ◽  
David A Clizer ◽  
Christian Ramirez-Camba ◽  
Ryan S Samuel ◽  
Crystal L Levesque

Abstract This experiment evaluated the effect of dietary protease supplementation on pig’s growth performance and post-weaning diarrhea in a 43-d trial. A total of 936 weaned pigs [21 d of age, initial BW 5.87 ± 0.31 kg] were used in a 2 × 2 factorial design (2 nutritional levels × 2 protease levels). The nutritional levels corresponded to a standard feeding program and a reduced feeding program (15% lower SID Lys) and without or with protease supplementation (0.0125% inclusion). Piglets were distributed in 36 pens with 26 pigs per pen and 9 replicates per dietary treatment. Pigs received a common Phase 1 diet and experimental diets in Phase 2, 3, and 4, (0.91, 3.4, 4.5, and 24.0 kg/pig, respectively). Phytase was included at 2,500 U in Phase 2 – 4, all diets met energy and AA:Lys requirements for nursery pigs. Feed intake and body weight were determined every 2 weeks. A pen fecal score assessment was performed at d7, 10, and 14. Performance data were analyzed using the PROC MIXED procedure and fecal score data using the PROC FREQ procedure (SAS Inst., Inc., Cary, NC). No significant interactions (P &gt; 0.05) were observed between dietary treatments. From d15 to 43 and during overall experimental period, pigs fed standard diets had greater BW, ADG, and G:F (P &lt; 0.05) than pigs fed deficient diets (Table 1). On d7, pigs fed deficient diet had more (X2 &lt; 0.05) soft and watery feces, and consequently less normal feces compared to pigs fed standard diets (Figure 1). On d7, 10, and 14, pigs fed diets with protease supplementation had more (X2 &lt; 0.05) normal feces compared to control pigs. Overall, effects of dietary protease supplementation on growth performance were not expressive under the conditions of this study but protease addition benefited intestinal health of nursery pigs.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 201-201
Author(s):  
Sudario Roberto Silva Junior ◽  
Rhuan F Chaves ◽  
Maíra Resende ◽  
Ygor Henrique De Paula ◽  
Kenio De Gouvêa Cabral ◽  
...  

Abstract Antibiotics growth promoting (AGP) in animal feed has been restricted. With this, several additives have been tested in order to replace AGP and ensure intestinal health. The objective of this study was to evaluate the effects of a blend of additives on growth performance, diarrhea incidence and cecal content microbiota of nursery pigs. A total of 576 weaned pigs (6.21 ± 1.16 kg) were assigned into 4 treatments (12 replicates) in randomized block design: basal diet without additives (NC); basal diet with 120 ppm of halquinol (PC); NC + 0,05% blend of lactic acid (3,5%), benzoic acid (2,5%), flavonoids (3,5%) (B5); NC+ 0,1% of same blend (B10). The pigs were weighed 0 and 42 days into the experiment. On day 10, one animal per pen (10 replicates) was euthanized for microbiota analyses. The diarrhea incidence was calculated by the percentage of visual pens with diarrhea, by day, in the period. The growth performance was analyzed by GLIMMIX procedure and the means were compared with Tukey test (P &lt; 0.050) (SAS, 2009). Diarrhea incidence was analyzed by GENMOD procedure (SAS, 2009). The Kruskal Wallis test was used to compare microbial biodiversity (P &lt; 0.050) by statistical program STAMP. The final weight (P = 0.010) and average daily gain (P = 0.001) of B10 and PC were higher than NC. Regarding diarrhea, it was observed that the B5 and B10 had lower incidence when compared to other groups in the total period. In the microbiome analyses, it was observed that the B5, B10, and PC groups had lower (P = 0.021) biodiversity when compared to the NC piglets. However, the B5 and B10 group had higher biodiversity when compared to the PC group. In conclusion, the supplementation with 0,1% blend of additives can be a substitute for AGP.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 94-95
Author(s):  
Kelsey Hammers ◽  
Hilda I Calderon ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
Robert D Goodband ◽  
...  

Abstract A total of 360 pigs (DNA 200′400, initially 5.0 kg) were used in a 45-d growth trial to determine the effects of fiber source and crude protein (CP) level in diets without pharmacological levels of ZnO on nursery pig growth performance and fecal dry matter (DM). Pigs were randomly assigned to 1 of 8 treatments with 5 pigs/pen and 9 pens/treatment. Treatments were arranged in a 2×4 factorial with main effects of CP (21 or 18%) and fiber source [none, coarse wheat bran (CWB), oat hulls, or cellulose (Arbocel, J. Rettenmaier USA, Schoolcraft, MI)]. Fiber source was added to equalize the level of insoluble fiber contributed from 4% CWB, resulting in the addition of 1.85% oat hulls or 1.55% cellulose. Diets were fed in two phases (d 0 to 10 and 10 to 24) followed by a common diet (d 24 to 45). The 21% CP diets contained 1.40% SID Lys in phase 1 and 1.35% SID Lys in phase 2. Treatment diets were formulated to a maximum SID Lys:digestible CP level of 6.35%, thus SID Lys decreased in the 18% CP (1.25% SID Lys) diets. Data were analyzed using the lmer function in R. No fiber source × CP level interactions (P &gt;0.05) were observed. Decreasing dietary CP decreased (P = 0.05) ADG, G:F, and d 24 BW. Overall, ADG and d 45 BW decreased (P &lt; 0.05) for pigs fed 18% CP diets. No main effects of fiber source were observed for growth performance throughout the study. Fecal DM increased (P &lt; 0.05) for pigs fed added cellulose compared to pigs fed no fiber or CWB in the experimental period. In conclusion, reducing dietary CP decreased growth performance and the inclusion of cellulose improved fecal DM of nursery pigs.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 22-23
Author(s):  
Richard A Mudarra ◽  
Tsung Cheng Cheng Tsai ◽  
Kristopher Bottoms ◽  
Thomas S Shieh ◽  
Casey Bradly ◽  
...  

Abstract To evaluate the effect of bioactive peptide (P) in combination with high level of zinc (HZ) or acidifiers on growth performance, complete blood cell counts (CBC) and nutrient digestibility in nursery pigs, a total of 288 weaned pigs (PIC1050xDNA600) were stratified by initial BW within gender and allotted to 1of 7 treatments. Treatments for phase 1&2 were: 1) nutrient adequate positive control with HZ (PC), 2) nutrient deficient negative control with HZ (NC, -0.13% SID Lysine by reducing fish meal), 3) NC+0.25% peptide (0.25PZ), 4) NC+0.5% peptide (0.5PZ), 5) NC+0.25% peptide with standard zinc (0.25P), 6) NC+0.5% peptide with standard zinc (0.5P), 7) as 5 + 0.1% sodium butyrate and 0.5% benzoic acid (PSB). All pigs were fed a common low Zn diet (197 ppm) during phase 3. The whole blood was obtained from a close-to-average pen-BW pig repeatedly at weaning, and at the end of phase 2 and 3 to determine CBC. Titanium dioxide was used as an indigestible marker to determine nutrient digestibility. Data were analyzed using the Mixed procedures of SAS as a RCBD with treatment as fixed effect, and BW block as random effect. In overall phase 1&2, pigs fed PSB had similar ADG and BW when compared to pigs fed 0.25PZ and both were greater than NC pigs (Table 1). With the same inclusion rate of peptide, pigs fed a high zinc diet had greater BW and ADG than pigs fed a standard zinc diet. PSB pigs had the greatest G:F ratio and nitrogen digestibility among treatments. Increasing peptide in high zinc diets gradually decreased Neutrophil-to-lymphocyte ratio. This study indicates that the improvement in growth performance from pigs fed peptide is pharmaceutical zinc dependent and acidifiers can be an alternative to replace ZnO without affecting growth performance.


2019 ◽  
Vol 3 (4) ◽  
pp. 1254-1262 ◽  
Author(s):  
Qingyun Li ◽  
Stacie A Gould ◽  
John Khun Kyaw Htoo ◽  
J Caroline González-Vega ◽  
John F Patience

Abstract The objective of this study was to evaluate the relative bioavailability (RBV) of l-Lys sulfate in comparison to l-Lys HCl based on the growth performance response from approximately 26 to 48 kg and from approximately 68 to 114 kg. The effect of Lys source on blood urea nitrogen (BUN), digestibility of dry matter (DM) and sulfur (S), as well as carcass characteristics was determined. A total of 280 growing pigs (25.9 ± 0.25 kg BW) were randomly assigned to one of seven dietary treatments in 56 pens, with five pigs per pen. The diets included a Lys-deficient basal diet (65% of requirement) and the basal diet supplemented with three graded levels of Lys (75%, 85%, and 95% of requirement), as either l-Lys HCl (78.8% Lys purity) or l-Lys sulfate (54.6% Lys purity). The experiment lasted for 112 d, with four dietary phases: Phase 1 lasted for 4 wk (BW: 25.9 to 47.5 kg), Phase 2 lasted for 3 wk (common commercial diet as washout period), Phase 3 lasted for 5 wk (BW: 67.5 to 98.2 kg), and Phase 4 lasted for 3 or 4 wk to reach an average market weight of 114.2 kg. Fresh fecal samples of pigs fed the highest levels of Lys (both Lys sources) were collected on 7 to 10 days after the beginning of Phase 3 for digestibility assay. Blood samples were collected on day 21 and day 81 to determine BUN. Carcass data were collected at a commercial packing plant. Data were analyzed using PROC GLM of SAS (9.4) according to a completely randomized design with pen as the experimental unit. The RBV of l-Lys sulfate was determined using the multiple regression slope-ratio method. Increasing levels of Lys, independent of source, increased (P &lt; 0.05) BW, ADG, and feed efficiency during Phases 1, 3, and 4; market BW increased linearly (P &lt; 0.01) and backfat and BUN decreased linearly (P &lt; 0.01). Lysine source had no impact on growth performance, carcass characteristics, BUN, or digestibility of S and DM. The RBV of l-Lys sulfate compared with l-Lys HCl was also not different based upon ADG or G:F during Phase 1, 3, or 4. These data suggest that the bioavailability of Lys in l-Lys sulfate and l-Lys HCl is at least equivalent for growing–finishing pigs.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 88-89
Author(s):  
Henrique S Cemin ◽  
Mike D Tokach ◽  
Aaron M Gaines ◽  
Brent W Ratliff ◽  
Steve S Dritz ◽  
...  

Abstract Two experiments were conducted to determine the effects of soybean meal (SBM) level in diets with or without distillers dried grains with solubles (DDGS) on growth performance of late nursery pigs. A total of 1,064 and 1,011 pigs (PIC 280×1050; initially 10.5 ± 0.36 and 10.9 ± 0.22 kg) were used in Exp. 1 and 2, respectively, with 21 to 27 pigs per pen. Pens were assigned to treatments in a randomized complete block design with 7 replicates per treatment per experiment. Treatments 1 to 3 were diets with 23% DDGS and 21, 27, or 35% SBM. Treatments 4 and 5 were corn-SBM diets with 27 or 35% SBM. Diets were balanced to 1.30% standardized ileal digestible lysine and 2,606 kcal of net energy/kg. Data were analyzed with the GLIMMIX procedure of SAS with pen as the experimental unit and block as random effect. There was no evidence for treatment × experiment interactions, thus data from both trials were combined. Feeding diets with 23% DDGS decreased (P = 0.033) ADFI and improved (P = 0.033) G:F compared to corn-SBM diets, which may indicate underestimation of DDGS net energy. When analyzed as a factorial with or without DDGS, pigs fed diets with 35% SBM had a tendency (P = 0.052) for increased ADG and improved (P = 0.001) G:F compared with diets with pigs fed 27% SBM. As SBM increased from 21 to 35% in diets with DDGS, ADG (linear, P = 0.001) and G:F (quadratic, P = 0.007) improved. In summary, feeding diets with increasing SBM improved growth performance in late nursery pigs.


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