122 Physiological effects of low level laser therapy on exercised horses

Abstract Low level laser therapy (LLLT) is a form of phototherapy which may stimulate healing of injuries and lesions from exercise. Our objective was to determine effects of LLLT before or after exercise on equine serum concentrations of cortisol, lactate, and cytochrome P450 (CYP) inhibition. Twelve quarter horses were randomly assigned to one of three groups: (A) received no laser therapy, (B) received six minutes of laser therapy before exercise, and (C) received six minutes of laser therapy after exercise. Laser (635 nm) treatment was with a class II handheld low-level laser with constant wave modulation. Horses were exercised using a walker for 30 min five days a week for three weeks, and within 30 min after exercise blood was collected on day 7, 14, and 21; blood was collected on day 0 prior to exercise as a reference point. Serum was collected, frozen; and cortisol, lactate, and CYP inhibition were determined via validated assays. Data were analyzed by ANOVA with horse as the experimental unit; an interaction (P < 0.05) between treatment group and day of study affected serum concentrations of cortisol, lactate, and CYP inhibition. For group B horses, cortisol concentrations decreased (P < 0.001) from day 14 to day 21 (31 vs 20 ± 2.9 ng/mL). Serum lactate concentrations increased (P < 0.0001) during the three weeks of training (2700, 2773, 3064, and 6061 ± 232 μM; respectively for day 0, 7, 14, and 21); whereas, inhibition of CYP decreased (P < 0.01) from day 0 to day 21. Interaction of main effects on lactate can be explained by larger increases in lactate concentrations for horses treated with LLLT during the trial; conversely, CYP inhibition decreased for horses treated with LLLT after exercise. Our results suggest that LLLT may be useful in improving performance of equine athletes.

Download Full-text

121 Physiological effects of low level laser therapy on exercised horses

Journal of Animal Science ◽

10.1093/jas/skz397.077 ◽

2020 ◽

Vol 98 (Supplement_2) ◽

pp. 34-34

Author(s):

Ashley Rosenkrans ◽

Carson Freeman ◽

Erin L Oberhaus ◽

Palika Dias Morse ◽

Charles Rosenkrans

Keyword(s):

Laser Therapy ◽

Serum Lactate ◽

Low Level Laser Therapy ◽

Experimental Unit ◽

Serum Concentrations ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Cyp Inhibition ◽

Group B

Abstract Low level laser therapy (LLLT) is a form of phototherapy, which may stimulate healing of injuries and lesions from exercise. Our objective was to determine effects of LLLT before or after exercise on equine serum concentrations of cortisol, lactate, and cytochrome P450 (CYP) inhibition. Twelve quarter horses were randomly assigned to one of three groups: (A) received no laser therapy, (B) received six minutes of laser therapy before exercise, and (C) received six minutes of laser therapy after exercise. Laser (635 nm) treatment was with a class II handheld low-level laser with constant wave modulation. Horses were exercised using a walker for 30 min five days a week for three weeks. Within 30 min after exercise blood was collected on day 7, 14, and 21; blood was collected on day 0 prior to exercise as a reference point. Serum was collected, frozen; and cortisol, lactate, and CYP inhibition were determined via validated assays. Data were analyzed by ANOVA with horse as the experimental unit; an interaction (P < 0.05) between treatment group and day of study affected serum concentrations of cortisol, lactate, and CYP inhibition. For group B horses, cortisol concentrations decreased (P < 0.001) from day 14 to day 21 (31 vs 20 ± 2.9 ng/mL). Serum lactate concentrations increased (P < 0.0001) during the three weeks of training (2700, 2773, 3064, and 6061 ± 232 μM; respectively for day 0, 7, 14, and 21); whereas, inhibition of CYP decreased (P < 0.01) from day 0 to day 21. Interaction of main effects on lactate can be explained by larger increases in lactate concentrations for horses treated with LLLT during the trial; conversely, CYP inhibition decreased for horses treated with LLLT after exercise. Our results suggest that LLLT may be useful in improving performance of equine athletes.

Download Full-text

Neovascularization: topical effects of streptococcus thermophilus and low level laser therapy in treatment of diabetic wound in rats

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20193913 ◽

2019 ◽

Vol 7 (9) ◽

pp. 3357

Author(s):

Devi Kumari ◽

Hina Khan ◽

Asad R. Jiskani ◽

Muhammad Rafique ◽

Muhammad Asif ◽

...

Keyword(s):

Blood Vessel ◽

Laser Therapy ◽

Streptococcus Thermophilus ◽

Low Level Laser Therapy ◽

Blood Vessel Formation ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Group A ◽

Group B

Background: Diabetic wound is a major socioeconomic debilitating problem in this society. Various treatment options are available but still it requires better treatment option. In diabetes mellitus the oxygenation to the tissues is reduced. In this study effects of low level laser therapy were compared with topical application of Streptococcus thermophilus on diabetic wounds that induces formation of new blood vessel and free radical scavenging system, a comparative study to get better treatment option for diabetic wounds.Methods: 18 male rats were selected and divided randomly into three groups. Diabetes was induced in all the rats by using the Alloxan monohydrate at a dose of 120mg/kg of the body weight. Group A was treated with normal saline, group B was treated with low level laser therapy and group C was treated with Streptococcus thermophilus topically. Skin tissues were collected on day three and seven, slides were prepared for microscopic examination to observe the new blood vessels formation.Results: Mean number of new blood vessel formation was observed in group B compared with group A and C. Significant vasculogenesis was seen in group B when treated with Low level laser therapy.Conclusions: In the group of low level laser therapy new blood vessel formation was seen with better wound healing. It means LLLT provides better oxygenation to the tissues by generation of new blood vessels compared with Streptococcus thermophilus and normal saline.

Download Full-text

Comparative Efficacy of Low level Laser Therapy And Pulsed Ultrasound in the Management of Second - Degree Contusion

Nigerian Journal of Medical Rehabilitation ◽

10.34058/njmr.v11i2.15 ◽

2007 ◽

Author(s):

O Ayanniyi ◽

O B Ogunkunle ◽

C E Mbada

Keyword(s):

Laser Therapy ◽

Low Level Laser Therapy ◽

Comparative Efficacy ◽

Pulsed Ultrasound ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Group A ◽

Group B ◽

Second Degree

Low level LASER therapy (LLLT) and pulsed ultrasound have been shown to relieve pain, promote healing and tissue repair in sport injuries. The objective of this study was to investigate the comparative efficacy of LLLT and pulsed ultrasound in the management of second - degree contusion in sportsmen. This is a 2 group pre-test – post-test quasi – experimental study involving 20 sportsmen, ten were in Group A (LLLT) and ten in Group B (P-US). They were aged between 19 and 30 years with the mean age 24.9 ± 3.28 years and 27.4 ± 3.75 years for the Group A and Group B respectively. Treatment consisted of six sessions, in a period of 2 weeks. Data collected on each participants included age, weight, height, site of injury, pain intensity, swelling, calf girth and range of motion. The result of the study revealed decrease in pain for both LLLT and pulsed ultrasound (p0.05). It was concluded that both therapies are equally effective in the management of pain resulting from second – degree contusion in sportsmen. KEYWORDS: Low level LASER, pulsed ultrasound, second – degree contusions.

Download Full-text

Effect of Low-Level Laser Therapy versus Electroacupuncture on Postnatal Scanty Milk Secretion: A Randomized Controlled Trial

American Journal of Perinatology ◽

10.1055/s-0039-1693428 ◽

2019 ◽

Vol 37 (12) ◽

pp. 1243-1249

Author(s):

Ahmed M. Maged ◽

Marwa E. Hassanin ◽

Wafaa M. Kamal ◽

Amr H. Abbassy ◽

Mahmoud Alalfy ◽

...

Keyword(s):

Laser Therapy ◽

Low Level Laser Therapy ◽

Serum Prolactin ◽

Milk Secretion ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Group A ◽

The Mean ◽

Group B

Abstract Objective Postnatal scanty milk secretion is a common complaint. Some physical and medical interventions were advocated to help milk production. These interventions should be effective and safe for the mother and the infant. This study aimed to compare the effects of low-level laser therapy and electroacupuncture on postnatal scanty milk secretion. Study Design A randomized controlled study conducted on 60 healthy primiparous mothers with insufficient lactation. They were randomly divided into three equal groups: group A (control), group B (those who received low-power He–Ne laser beam on both breasts), and group C (those who received faradic current stimulation at Spleen 6, Liver 3, and Small Intestine 1 acupuncture points on both sides). All participants received 10 mg Domperidone three times a day and were given advice about lactation, nutrition, and fluid intake. Evaluation was done before and after the treatment program. Results The mean serum prolactin, infant weight, and visual analog scale (VAS) score were significantly increased in the three groups posttreatment when compared with their corresponding levels pretreatment. Posttreatment serum prolactin was significantly elevated in group C more than the other two groups (p = 0.001 and 0.012, respectively). Also, it was significantly elevated in group B more than in group A (p = 0.001). The mean value of infant weight was significantly elevated in group C when compared with its corresponding values in both groups A (p = 0.001) and B (p = 0.029). The VAS score was significantly increased in both groups B and C when compared with group A (p = 0.001). Conclusion Electroacupuncture is more effective than low-level laser therapy in increasing postnatal scanty milk secretion. Clinical Trial Registration NCT03806062.

Download Full-text

Evaluation of low level laser and interferential current in the therapy of complex regional pain syndrome by infrared thermographic camera

Vojnosanitetski pregled ◽

10.2298/vsp1009755k ◽

2010 ◽

Vol 67 (9) ◽

pp. 755-760 ◽

Cited By ~ 6

Author(s):

Mirjana Kocic ◽

Milica Lazovic ◽

Irena Dimitrijevic ◽

Dragan Mancic ◽

Anita Stankovic

Keyword(s):

Laser Therapy ◽

Pain Syndrome ◽

Low Level Laser Therapy ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Before And After ◽

Interferential Current ◽

Group A ◽

Group B

Background/Aim. Complex regional pain syndrome type I (CRPS I) is characterized by continuous regional pain, disproportional according to duration and intensity and to the sort of trauma or other lesion it was caused by. The aim of the study was to evaluate and compare, by using thermovison, the effects of low level laser therapy and therapy with interferential current in treatment of CRPS I. Methods. The prospective randomized controlled clinical study included 45 patients with unilateral CRPS I, after a fracture of the distal end of the radius, of the tibia and/or the fibula, treated in the Clinical Centre in Nis from 2004 to 2007. The group A consisted of 20 patients treated by low level laser therapy and kinesy-therapy, while the patients in the group B (n = 25) were treated by interferential current and kinesy-therapy. The regions of interest were filmed by a thermovision camera on both sides, before and after the 20 therapeutic procedures had been applied. Afterwards, the quantitative analysis and the comparing of thermograms taken before and after the applied therapy were performed. Results. There was statistically significant decrease of the mean maximum temperature difference between the injured and the contralateral extremity after the therapy in comparison to the status before the therapy, with the patients of the group A (p < 0.001) as well as those of the group B (p < 0.001). The decrease was statistically significantly higher in the group A than in the group B (p < 0.05). Conclusions. By the use of the infrared thermovision we showed that in the treatment of CRPS I both physical medicine methods were effective, but the effectiveness of laser therapy was statistically significantly higher compared to that of the interferential current therapy.

Download Full-text

Efficacy of Cyriax Physiotherapy versus Cyriax and low level Laser Therapy on pain and grip strength in Lateral Epicondylitis

Bangladesh Journal of Medical Science ◽

10.3329/bjms.v20i2.51548 ◽

2021 ◽

Vol 20 (2) ◽

pp. 356-360

Author(s):

Sunita Sharma ◽

Nitin Gupta ◽

Sandeep Joshi ◽

Rosy Bala ◽

Ruby Sharma

Keyword(s):

Grip Strength ◽

Laser Therapy ◽

Medical Science ◽

Lateral Epicondylitis ◽

Low Level Laser Therapy ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Group A ◽

Group B

Objective: The study was designed to evaluate the efficacy of Cyriax physiotherapy versus Cyriaxand Low Level Laser Therapy to compare these techniques in reducing pain and improving gripstrength in patients with lateral epicondylitis. Methodology: The study population included 30patients of lateral epicondylitis (signs and symptoms present for more than 6 weeks) diagnosedin outpatient and indoor facilities of MM Hospital, Mullana. The subjects were selected bymeans of simple random sampling. After fulfilling the inclusion and exclusion criteria, thepatients were randomly allocated in two groups: Group A and Group B. Group A received cyriaxphysiotherapy alone whereas Group B patients were subjected to combined Cyriax and low levelLaser therapy. Baseline measurements of pain and grip strength were taken before treatmentand then at 3 weeks respectively. Results: Our findings showed that there was significantlyhigher improvement in pain and grip strength in Group B (patients receiving combination ofcyriax therapy with low dose laser therapy) as compared to Group A (p<0.05). Conclusion:Cyriax physiotherapy and low level laser therapy were effective in reducing pain and improvinggrip strength after the treatment sessions. But benefits of cyriax physiotherapy with low levellaser therapy in lateral epicondylitis patients are significantly higher as compared to cyriaxphysiotherapy alone over a three week period. Hence, cyriax with low level laser therapy isproved to be a better treatment. Bangladesh Journal of Medical Science Vol.20(2) 2021 p.356-360

Download Full-text

Comparative evaluation of low level laser therapy in post endodontic pain management - A quasi experimental trial

RGUHS Journal of Dental Sciences ◽

10.26715/rjds.12_2_3 ◽

2020 ◽

Vol 12 (2) ◽

pp. 7-12

Author(s):

Dr. Kiran Kumar N ◽

Dr. Seema Merwade ◽

Dr. Pavithra Prabakaran ◽

Dr. Savitha B. Naik ◽

Dr. B Brigit ◽

...

Keyword(s):

Pain Management ◽

Laser Therapy ◽

Low Level Laser Therapy ◽

Control Group ◽

Average Output ◽

Single Visit ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Group B

Introduction: Low level lasers have an average output power range between 5 and 500 mW. Low level lasers have shown nonthermal, and bio-stimulatory effects. The most common complication of single visit endodontics is a flare-up that results in pain and swelling. Aim:The aim of this clinical study was to evaluate the effect of Low Level Laser Therapy in pain management after single visit endodontic treatment pain. Materials and methods: Thirty subjects with symptomatic apical periodontitis in their lower premolars were divided randomly into 3 groups. Group A was administered Low level Laser for 5 minutes prior to the procedure at the apex of the tooth through buccal mucosa and into the canal after pulp space preparation. Group B was given 600 milligrams of ibuprofen half an hour prior to the start of the treatment and given Low level Laser just prior to the treatment and into the canal after the completion of pulp space preparation. Group C was kept as a control group which was neither given analgesics nor laser preoperatively.Intensity of pain after treatment was noted down on a visual analog scale at four hour, eight hour,twelve hour and twenty four hour interval. Results: Results were obtained after statistical analysis. Conclusion: LLLT group showed less pain levels than the control group after single visit endodontics.

Download Full-text

Assessment of healing of dental implant surgical site following Low-Level Laser Therapy using Bio-Clinical parameters: An Exploratory Study

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-18-00316 ◽

2020 ◽

Author(s):

VARSHA PALLED ◽

DR. JITENDRA RAO ◽

DR. RAGHUWAR DAYAL SINGH ◽

DR. SHUCHI TRIPATHI ◽

DR. KALPANA SINGH ◽

...

Keyword(s):

Laser Therapy ◽

Test Group ◽

Low Level Laser Therapy ◽

Control Group ◽

Clinical Parameters ◽

Implant Stability ◽

Low Level ◽

Implant Stability Quotient ◽

Low Level Laser ◽

Level Laser

The purpose of this study was to evaluate whether Low-Level Laser Therapy (LLLT) improves the healing of the implant surgical site with clinical and biochemical parameters.Thirty patients with an edentulous space spanning a single tooth were selected. The patients were randomly allocated to two groups - the control group and the test group. The test group received laser energy at a power of 2J/cm 2 with a total of 4-6J energy over each implant. Clinical parameters (Implant Stability Quotient, probing index, modified sulcus bleeding index)and osteoprotegerin (OPG) were assessed at baseline and follow-up intervals (2 weeks, 6 weeks, and 3 months).The test group showed significantly higher implant stability quotient compared to thecontrol group at 2 weeks(57.93±3.95 and 35.67±3.08; p<0.01) and 3months(58.86±3.75 and 67.06±3.78; p<0.01). A significant rise in OPG levels of the test group(686.30±125.36pg/ml at baseline and 784.25±108.30pg/ml at 3months;p<0.01) was seen contrary to significant decline in the control group (839.50±249.08pg/ml at baseline,415.30±78.39pg/ml at 3months;p<0.01). Within the limitations of the study, the study suggests that the healing of peri-implant hard and soft tissues may be enhanced with the use of LLLT as an explicit modality during the post-operative period.

Download Full-text