scholarly journals A129 VIDEOCAPSULE ENDOSCOPY RETENTION: WHAT ARE THE RISK FACTORS?

2021 ◽  
Vol 4 (Supplement_1) ◽  
pp. 112-113
Author(s):  
S Li Fraine ◽  
C Langevin ◽  
N Mahdi ◽  
M Bouin
Keyword(s):  
Risk Factors ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Abdominal Surgery ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Iron Deficient ◽  
Increased Risk ◽  
Videocapsule Endoscopy

Abstract Background The most feared complication of videocapsule endoscopy (VCE) is retention in the intestine. It is estimated to occur in 1.4% of cases but the risk factors are not well known. Aims To determine the prevalence of VCE retention at a tertiary care centre as well the associated risk factors. Methods Retrospective study between 2016 and 2019. All patients at a tertiary care centre undergoing VCE were recruited. The patients with an incomplete endoscopy report or who were unable to complete VCE were excluded. Clinical and endoscopic information was compiled from patients’ medical charts as well as the indications and results of the endoscopic procedure. VCE retention, evaluated by radiography or CT scan, was defined as persistence of the videocapsule in the gastrointestinal tract for ≥14 days or the need for an intervention for removal. Results In total, 126 patients underwent VCE (average age: 66±16, 52% female). There was 6% of patients with Crohn’s disease, and 40% of patients had a previous abdominal surgery. The indications for endoscopy were: iron deficient anemia (48%), gastrointestinal bleeding (32%), suspicion/follow up of IBD (10%), and other (11%). The VCE findings (n=146) were: angiodysplasia (30%), inflammation (30%), normal (20%), polyp (5%), and other (15%). 77% of results were not previously found by conventional endoscopy or imaging. The prevalence of VCE retention was 1.6%. The patient risk factors for retention were Crohn’s disease (OR 19.67; 95CI 1.09–354.11; p<0.05) and corticosteroid use in the previous 2 weeks (OR 19.67; 95CI 1.09–354.11; p<0.05). There was no risk of retention associated with ulcerative colitis, sex, abdominal surgery, or opioid use. The finding of stenosis on VCE was associated with an increased risk of retention (OR 123; 95% CI 4.11-3683.43; p<0.01). Conclusions VCE retention remains a rare complication. There is increased risk of retention in patients with known Crohn’s disease or recent use of corticosteroids. Funding Agencies None

The safety and efficacy of adalimumab in patients with Crohn's disease: the experience of a single Canadian tertiary care centre

2013 ◽  
Vol 49 (3) ◽  
pp. 280-286 ◽  
Author(s):  
Anouar Teriaky ◽  
James Gregor ◽  
Brian Yan ◽  
Terry Ponich ◽  
Nilesh Chande ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Safety And Efficacy

scholarly journals P206 The prevalence of asymptomatic early sacroiliitis in Crohn’s disease patients: The single experience of an Italian tertiary care centre

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S203-S203
Author(s):  
M Di Girolamo ◽  
F Campomori ◽  
A Spinelli ◽  
A Sartini ◽  
G Sandri ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre

Small bowel capsule endoscopy for management of Crohn's disease: A retrospective tertiary care centre experience

2013 ◽  
Vol 45 (7) ◽  
pp. 558-561 ◽  
Author(s):  
Catherine Dussault ◽  
Corinne Gower-Rousseau ◽  
Julia Salleron ◽  
Gwénola Vernier-Massouille ◽  
Julien Branche ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Capsule Endoscopy ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre

scholarly journals Maternal and fetal outcome in abruptio placentae at a tertiary care centre: a retrospective analysis

2021 ◽  
Vol 10 (10) ◽  
pp. 3860
Author(s):  
Jessica C. Fernandes ◽  
Nandini Gopalakrishna
Keyword(s):  
Risk Factors ◽  
Early Intervention ◽  
Placental Abruption ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Timely Diagnosis ◽  
Increased Risk ◽  
Abruptio Placenta

Background: Placental abruption is a major obstetric complication leading to increased risk of maternal and neonatal morbidity and mortality globally. Placental abruption is traditionally defined as premature separation of a normally implanted placenta after 20 weeks of gestation and before delivery of the fetus. Early recognition of the risk factors, timely diagnosis and early intervention can significantly reduce maternal and fetal morbidity and mortality. This study was aimed to identify the associated risk factors with abruptio placenta and to analyse the maternal and perinatal outcome in abruptio placenta.Methods: This was a retrospective observational study, from Jan 2016 to Dec 2019 at M.S. Ramaiah medical college and hospitals, Bangalore.Results: In our study, the incidence of abruptio placenta was 0.95%. Majority of our patients were between 20-24 years (41.5%). Primigravidae accounted for 46.15% of the cases. The unbooked cases were 92%. The commonest risk factor was hypertension complicating pregnancy which accounted for 26% .The live births were 64%. Postpartum haemorrhage was one of the major complications in our study. There was no maternal mortality, probably due to early intervention and availability of blood and blood products.Conclusions: Timely diagnosis and appropriate intervention preferably in tertiary care centre will significantly reduce mortality and morbidity in both mother and fetus.  

Ustekinumab use in Crohn’s disease: a Canadian tertiary care centre experience

2017 ◽  
Vol 52 (12) ◽  
pp. 1354-1359 ◽  
Author(s):  
Astrid-Jane Greenup ◽  
Greg Rosenfeld ◽  
Brian Bressler
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre

scholarly journals Clinical profile and risk factors for mortality among COVID-19 inpatients at a tertiary care centre in Bengaluru, India

2021 ◽  
Author(s):  
Yamini Marimuthu ◽  
Radhika Kunnavil ◽  
NS Anil ◽  
Sharath Burugina Nagaraja ◽  
N Satyanarayana ◽  
...  
Keyword(s):  
Risk Factors ◽  
South India ◽  
Linear Models ◽  
Tertiary Care ◽  
Male Gender ◽  
Clinical Profile ◽  
Rank Test ◽  
Care Hospital ◽  
Care Centre ◽  
Tertiary Care Centre

COVID-19 is an emerging viral disease affecting more than 200 countries worldwide and it present with varied clinical profile throughout the world. Without effective drugs to cure COVID-19, early identification and control of risk factors are important measures to combat COVID-19.  This study was conducted to determine the clinical profile and risk factors associated with mortality among COVID-19 patients in a tertiary care hospital in South India. This record-based longitudinal study was conducted by reviewing the case records of COVID-19 patients admitted for treatment from June 2020 to September 2020 in a tertiary care centre in South India. The clinical details, discharge/death details, were collected and entered in MS Excel. Potential risk factors for COVID-19 mortality were analysed using univariate binomial logistic regression, generalized linear models (GLM) with Poisson distribution. Survival curves were made using the Kaplan-Meier method. Log-rank test was used to test the equality of survivor functions between the groups. Out of 854 COVID-19 patients, 56.6% were men and the mean (standard deviation) age was 45.3(17.2) years. The median survival time was significantly lesser in male COVID-19 patients (16 days) as compared to female patients (20 days). Increasing age, male gender, patients presenting with symptoms of fever, cough, breathlessness, smoking, alcohol consumption, comorbidities were significantly associated with mortality among COVID-19 patients. Patients with older age, male gender, breathlessness, fever, cough, smoking and alcohol and comorbidities need careful observation and early intervention.  Public health campaigns aimed at reducing the prevalence of risk factors like diabetes, hypertension, smoking and alcohol use are also needed.

scholarly journals Evaluation of Risk Factors for Retinopathy of Prematurity in Premature Born Infants in Tertiary Care Centre in Punjab

2020 ◽  
Vol 9 (1) ◽  
pp. 1-5
Author(s):  
Jatinder Singh ◽  
Vaneeta Bhardwar ◽  
Harshdhawann Singh ◽  
Isha Bhardwaj ◽  
Sushmita Choudhary ◽  
...  
Keyword(s):  
Risk Factors ◽  
Retinopathy Of Prematurity ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Premature Born

scholarly journals P050 Work Disability, Indirect Costs and Risk Factors in Patients With Crohn’s Disease in a Rio De Janeiro Tertiary Care Center

2020 ◽  
Vol 115 (1) ◽  
pp. S13-S13
Author(s):  
Fróes Renata ◽  
Moreira Andre ◽  
Carneiro Antônio José ◽  
Moreira Jessica ◽  
Luiz Ronir ◽  
...  
Keyword(s):  
Risk Factors ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Work Disability ◽  
Rio De Janeiro ◽  
Care Center ◽  
Tertiary Care ◽  
Indirect Costs ◽  
Tertiary Care Center

The Importance of Monitoring the Postpartum Period in Moderate to Severe Crohn’s Disease

2021 ◽  
Author(s):  
Audrey Bennett ◽  
Alexander Mamunes ◽  
Mindy Kim ◽  
Caroline Duley ◽  
Ailish Garrett ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Postpartum Period ◽  
Tertiary Care ◽  
Retrospective Chart Review ◽  
Outpatient Setting ◽  
Smoking During Pregnancy ◽  
Wilcoxon Rank Sum Test ◽  
Increased Risk ◽  
Biologic Medication

Abstract Background Prior research demonstrates Crohn’s disease patients often do well in pregnancy; however, less is known about the risk of flare in the postpartum period. Methods A retrospective chart review was conducted at a tertiary care inflammatory bowel disease center. All pregnant women with Crohn’s disease who were followed in the postpartum period, defined as 6 months after delivery, were included. Statistical analysis included χ 2 analysis, Wilcoxon rank sum test, and logistic regression analysis. The primary outcome of interest was rate of flare in the postpartum period. Results There were 105 patients included in the study, with a majority (68%) on biologic medication during pregnancy. Thirty-one patients (30%) had a postpartum flare at a median of 9 weeks (range 2–24 weeks). Twenty-five patients (81%) had their postpartum flare managed in the outpatient setting with medications (only 4 of these patients required prednisone). 6 of 31 patients (19%) were hospitalized at a median of 4 weeks (range 2–26 weeks) after delivery, requiring intravenous corticosteroids or surgery. In multivariable regression, there was no significant increase in risk of postpartum flare with increasing maternal age, flare during pregnancy, or steroid or biologic use during pregnancy. Smoking during pregnancy increased risk of postpartum flare (odds ratio, 16.2 [1.72–152.94], P < 0.05). Conclusion In a cohort of Crohn’s disease patients, 30% experienced a postpartum flare despite being on medical therapy, but most were able to be managed in the outpatient setting.

Sign in / Sign up

Export Citation Format

Share Document