scholarly journals The In Vivo Diagnosis of Concomitant Alzheimer and Lewy Body Pathology: A Case Report

2021 ◽  
Author(s):  
Lorenzo Muccioli ◽  
Angela Mammana ◽  
Alex Incensi ◽  
Simone Baiardi ◽  
Piero Parchi ◽  
...  
Keyword(s):  
Case Report ◽  
Lewy Body ◽  
Lewy Body Pathology ◽  
In Vivo Diagnosis

Low myocardial MIBG uptake in multiple system atrophy with incidental Lewy body pathology: An autopsy case report

2008 ◽  
Vol 23 (7) ◽  
pp. 1055-1057 ◽  
Author(s):  
Hiroshi Nagayama ◽  
Mineo Yamazaki ◽  
Masayuki Ueda ◽  
Yasuhiro Nishiyama ◽  
Makoto Hamamoto ◽  
...  
Keyword(s):  
Case Report ◽  
Multiple System Atrophy ◽  
Lewy Body ◽  
Autopsy Case ◽  
Mibg Uptake ◽  
Lewy Body Pathology

Parkinsonism in C9orf72 expansion without co‐existing Lewy body pathology; a case report and review of the literature

2020 ◽  
Vol 46 (7) ◽  
pp. 786-789
Author(s):  
S. Shivji ◽  
W. Wong ◽  
C. E. Fischer ◽  
L. R. Fornazzari ◽  
M. Masellis ◽  
...  
Keyword(s):  
Case Report ◽  
Lewy Body ◽  
Review Of The Literature ◽  
C9orf72 Expansion ◽  
Lewy Body Pathology

scholarly journals Aptamer Applications in Emerging Viral Diseases

2021 ◽  
Vol 14 (7) ◽  
pp. 622
Author(s):  
Arne Krüger ◽  
Ana Paula de Jesus Santos ◽  
Vanessa de Sá ◽  
Henning Ulrich ◽  
Carsten Wrenger
Keyword(s):  
Virus Assembly ◽  
Viral Diseases ◽  
Tissue Penetration ◽  
Rna Molecules ◽  
Viral Particles ◽  
Pharmacokinetic Properties ◽  
Oligonucleotide Library ◽  
In Vivo Diagnosis ◽  
Emerging Viral Diseases

Aptamers are single-stranded DNA or RNA molecules which are submitted to a process denominated SELEX. SELEX uses reiterative screening of a random oligonucleotide library to identify high-affinity binders to a chosen target, which may be a peptide, protein, or entire cells or viral particles. Aptamers can rival antibodies in target recognition, and benefit from their non-proteic nature, ease of modification, increased stability, and pharmacokinetic properties. This turns them into ideal candidates for diagnostic as well as therapeutic applications. Here, we review the recent accomplishments in the development of aptamers targeting emerging viral diseases, with emphasis on recent findings of aptamers binding to coronaviruses. We focus on aptamer development for diagnosis, including biosensors, in addition to aptamer modifications for stabilization in body fluids and tissue penetration. Such aptamers are aimed at in vivo diagnosis and treatment, such as quantification of viral load and blocking host cell invasion, virus assembly, or replication, respectively. Although there are currently no in vivo applications of aptamers in combating viral diseases, such strategies are promising for therapy development in the future.

High-Resolution Confocal Endomicroscopy Probe System for In Vivo Diagnosis of Colorectal Neoplasia

2008 ◽  
Vol 135 (1) ◽  
pp. 295 ◽  
Author(s):  
Anna M. Buchner ◽  
Marwan S. Ghabril ◽  
Murli Krishna ◽  
Herbert C. Wolfsen ◽  
Michael B. Wallace
Keyword(s):  
High Resolution ◽  
Colorectal Neoplasia ◽  
Confocal Endomicroscopy ◽  
Probe System ◽  
In Vivo Diagnosis

Multimodal endoscopic imaging and Raman spectroscopy for improving in vivo diagnosis of gastric malignancies during clinical gastroscopy

2010 ◽  
Author(s):  
Mads Sylvest Bergholt ◽  
Wei Zheng ◽  
Kan Lin ◽  
Khek Yu Ho ◽  
Khay Guan Yeoh ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Endoscopic Imaging ◽  
In Vivo Diagnosis

scholarly journals Real-time In vivo Diagnosis of Nasopharyngeal Carcinoma Using Rapid Fiber-Optic Raman Spectroscopy

Theranostics ◽  
2017 ◽  
Vol 7 (14) ◽  
pp. 3517-3526 ◽  
Author(s):  
Kan Lin ◽  
Wei Zheng ◽  
Chwee Ming Lim ◽  
Zhiwei Huang
Keyword(s):  
Raman Spectroscopy ◽  
Nasopharyngeal Carcinoma ◽  
Real Time ◽  
Fiber Optic ◽  
In Vivo Diagnosis

Linkage of Parkinsonism and Alzheimer's disease with Lewy body pathology to chromosome 12

2002 ◽  
Vol 52 (4) ◽  
pp. 524-524
Author(s):  
William K. Scott ◽  
Jeffery M. Vance ◽  
Jonathan L. Haines ◽  
Margaret A. Pericak-Vance
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Lewy Body ◽  
Chromosome 12 ◽  
Lewy Body Pathology
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