Weighing Physical Activity: The Impact of a Family-Based Group Lifestyle Intervention for Pediatric Obesity on Participants' Physical Activity

Introduction: The AHA created “Life’s Simple Seven” metrics to measure progress toward the goal of improving the cardiovascular (CV) health of all Americans, classifying each metric as “ideal”, “intermediate,” or “poor”. Few studies have examined the impact of behavioral lifestyle interventions on CV health metrics. We evaluated changes in CV health metrics during the course of a CDC recognized Diabetes Prevention Program-based lifestyle intervention known as Group Lifestyle Balance (DPP-GLB). Hypothesis: DPP-GLB will be associated with improvements in CV health metrics after 6 months of intervention and maintenance of these improvements at 12 months post-baseline. Methods: We used combined data from two similar intervention trials (occurring 6 years apart) offering a 12 month DPP-GLB program in the community setting to overweight/obese individuals with prediabetes and/or metabolic syndrome. Changes in individual CV health metrics (BMI, blood pressure, total cholesterol, fasting blood glucose, physical activity; measures of smoking and diet were not available) and total metric score (sum of metric profile where ideal=2, intermediate=1 and poor=0 for each metric, possible “total “range of 0-10) were considered after 6 and 12 months of intervention. Results: Among 222 participants (76%) with complete data for all 5 metrics at intervention baseline, 6 and 12 month follow up, there was a significant beneficial shift from baseline to 6 and 12 months in the proportion of participants within CV health metric categories for BMI, physical activity and blood pressure (Figure 1). Total metric score also improved significantly (p<0.01, signed-rank test) at 6 [median (IQR) change: +1.0 (0-1.0)] and 12 months [median (IQR) change: 0.0 (0-1.0)]. Significant improvement was also seen in the median number of ideal metrics at 6 and 12 months (p<0.01 for both). Conclusions: The DPP-GLB intervention was successful in improving CV health metrics at both 6 and 12 months, demonstrating the potential of this program to decrease CVD risk.

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Dietary Intakes and Physical Activity among Preschool-Aged Children Living in Rural American Indian Communities before a Family-Based Healthy Lifestyle Intervention

Journal of the American Dietetic Association ◽

10.1016/j.jada.2010.04.009 ◽

2010 ◽

Vol 110 (7) ◽

pp. 1049-1057 ◽

Cited By ~ 43

Author(s):

Tara L. LaRowe ◽

Alexandra K. Adams ◽

Jared B. Jobe ◽

Kate A. Cronin ◽

Suanne M. Vannatter ◽

...

Keyword(s):

Physical Activity ◽

American Indian ◽

Lifestyle Intervention ◽

Healthy Lifestyle ◽

Dietary Intakes ◽

Family Based ◽

Preschool Aged Children

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The effect of a lifestyle intervention in obese pregnant women on change in gestational metabolic profiles: findings form the UK Pregnancies Better Eating and Activity Trial (UPBEAT) RCT.

10.1101/125740 ◽

2017 ◽

Author(s):

Harriet Mills ◽

Nashita Patel ◽

Sara White ◽

Dharmintra Pasupathy ◽

Annette L Briley ◽

...

Keyword(s):

Physical Activity ◽

Fatty Acids ◽

Usual Care ◽

Pregnant Women ◽

Lifestyle Intervention ◽

Metabolic Profiles ◽

Obese Women ◽

Diet And Physical Activity ◽

The Uk ◽

The Impact

Background: Pregnancy metabolic disruption is believed to be enhanced in obese women and lead to adverse outcomes in them and their offspring. The UK Pregnancies Better Eating and Activity Trial (UPBEAT), a randomised controlled trial of a lifestyle intervention in obese pregnant women, has already been shown to improve diet and physical activity. We used UPBEAT to determine (a) the magnitude of change in metabolic profiles in obese pregnant women and (b) the impact of a lifestyle intervention that successfully improved diet and physical activity on these profiles. Methods: Detailed targeted metabolic profiling, with quantification of 158 metabolic features (129 lipid measures, 9 glycerides and phospholipids, and 20 low-molecular weight metabolites) was completed on three occasions (~17-, 28- and 35-weeks of gestation) in the UPBEAT participants using NMR. Random intercept and random slope models were used to quantify metabolite changes in obese women using the control (usual care) group only (N = 577). The effect of the intervention was determined by comparing rates of metabolite change between those randomised to intervention and usual care, using intention to treat analyses (N = 1158). Results: There were adverse changes across pregnancy in most lipoprotein subclasses, lipids, glycerides, phospholipids, several fatty acids and glucose. All extremely large, very large, large, medium, small and very small VLDL particles increased by 2 to 3 standard deviation units (SD), with IDL, and large, medium and small LDL particles increasing by 1 to 2SD, between 16- and 36-weeks. Triglycerides increased by 3 to 4SD and glucose increased by 2SD, with more modest changes in other metabolites. The intervention reduced the rate of increase in extremely large, very large, large and medium VLDL, in particular those containing triglycerides. Triglyceride to phosphoglyceride ratio was reduced and there were improvements in fatty acid profiles (increases in the proportion of all fatty acids that were linoleic, omega-6 and polyunsaturated and decreases in the proportion of saturated). Conclusion: Systemic metabolism is markedly disrupted in obese pregnant women, but a lifestyle intervention that improved their diet and physical activity has beneficial effects on some of these profiles; these effects might have long-term benefit. Clinical trial registration ID # ISRCTN89971375 .

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The effects of a 2-year individualized and family-based lifestyle intervention on physical activity, sedentary behavior and diet in children

Preventive Medicine ◽

10.1016/j.ypmed.2016.02.027 ◽

2016 ◽

Vol 87 ◽

pp. 81-88 ◽

Cited By ~ 25

Author(s):

Anna Viitasalo ◽

Aino-Maija Eloranta ◽

Niina Lintu ◽

Juuso Väistö ◽

Taisa Venäläinen ◽

...

Keyword(s):

Physical Activity ◽

Sedentary Behavior ◽

Lifestyle Intervention ◽

Family Based

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The impact of a randomized controlled trial of a lifestyle intervention on postpartum physical activity among at-risk hispanic women: Estudio PARTO

PLoS ONE ◽

10.1371/journal.pone.0236408 ◽

2020 ◽

Vol 15 (7) ◽

pp. e0236408

Author(s):

Sarah Burkart ◽

Bess H. Marcus ◽

Penelope Pekow ◽

Milagros C. Rosal ◽

JoAnn E. Manson ◽

...

Keyword(s):

Physical Activity ◽

At Risk ◽

Randomized Controlled Trial ◽

Lifestyle Intervention ◽

Hispanic Women ◽

Controlled Trial ◽

Randomized Controlled ◽

The Impact

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Obesity – A global Burden, Crucial Problem for the Society

Bangladesh Journal of Medicine ◽

10.3329/bjmed.v29i2.37942 ◽

2018 ◽

Vol 29 (2) ◽

pp. 75-83

Author(s):

Quazi Tarikul Islam ◽

Ishrat Binte Reza

Keyword(s):

Physical Activity ◽

Bariatric Surgery ◽

Weight Loss ◽

Lifestyle Intervention ◽

Global Public Health ◽

Health Crisis ◽

The Us ◽

And Behavior ◽

The Impact ◽

Care Costs

Objectives: To aware doctors, patients, food producers and consumers.Data source: Online search via Google, 70 articles were down loaded, 52 valid papers were selected. Only 12 full text articles were eligible for review. Obesity rates have increased sharply over the past 30 years, creating a global public health crisis. The impact of obesity on morbidity, mortality, and health care costs is profound. Obesity and weight related complications exert a huge burden on patient suffering and social costs. In recent years, exciting advances have occurred in all 3 modalities used to treat obesity: lifestyle intervention, pharmacotherapy, and weight-loss procedures including bariatric surgery. Obese individuals lose approximately 6 to 8 kg (approximately 6% to 8% of initial weight) with 6 months of participation in a high-intensity lifestyle intervention ($ 14 treatment visits) consisting of diet, physical activity, and behavior therapy. Such losses reduce progression to type 2 diabetes in at-risk people and decrease blood pressure and triglyceride levels. All diets, regardless of macronutrient composition, can produce clinically meaningful weight loss (.5%) if they induce a deficit of 500 kcal/d. Physical activity of 150 to 180 min/week yields modest short-term weight loss compared with diet but contributes to improvements in obesity-related conditions. Gradual weight regain is common after lifestyle intervention but can be prevented by continued participation in monthly weight loss maintenance sessions, as well as by high levels of physical activity (ie, 200 to 300min/wk). Patients unable to reduce satisfactorily with lifestyle intervention may be candidates for pharmacotherapy, recommended as an adjunct. Five medications have been approved by the US Food and Drug Administration for chronic weight management, and each has its own risk/benefit profile. The addition of these medications to lifestyle intervention increases mean weight loss by 2.5 to 8.9 kg compared with placebo. Patients with severe obesity who are unable to reduce successfully with lifestyle intervention and pharmacotherapy are eligible for bariatric surgery, including Roux-en-Y gastric bypass, sleeve gastrectomy, or adjustable gastric banding.Bangladesh J Medicine Jul 2018; 29(2) : 75-83

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