scholarly journals The influence of physique on dose conversion coefficients for idealised external photon exposures: a comparison of doses for Chinese male phantoms with 10th, 50th and 90th percentile anthropometric parameters

2017 ◽  
Vol 58 (5) ◽  
pp. 737-744 ◽  
Author(s):  
Wei Lv ◽  
Hengda He ◽  
Qian Liu
Keyword(s):  
Anatomical Variation ◽  
Radiation Risk ◽  
Organ Dose ◽  
Normal Weight ◽  
Adult Males ◽  
Fat Percentage ◽  
Anthropometric Parameters ◽  
Chinese Adult ◽  
Conversion Coefficients ◽  
The Difference

Abstract For evaluating radiation risk, the construction of anthropomorphic computational phantoms with a variety of physiques can help reduce the uncertainty that is due to anatomical variation. In our previous work, three deformable Chinese reference male phantoms with 10th, 50th and 90th percentile body mass indexes and body circumference physiques (DCRM-10, DCRM-50 and DCRM-90) were constructed to represent underweight, normal weight and overweight Chinese adult males, respectively. In the present study, the phantoms were updated by correcting the fat percentage to improve the precision of radiological dosimetry evaluations. The organ dose conversion coefficients for each phantom were calculated and compared for four idealized external photon exposures from 15 keV to 10 MeV, using the Monte Carlo method. The dosimetric results for the three deformable Chinese reference male phantom (DCRM) phantoms indicated that variations in physique can cause as much as a 20% difference in the organ dose conversion coefficients. When the photon energy was <50 keV, the discrepancy was greater. The irradiation geometry and organ position can also affect the difference in radiological dosimetry between individuals with different physiques. Hence, it is difficult to predict the conversion coefficients of the phantoms from the anthropometric parameters alone. Nevertheless, the complex organ conversion coefficients presented in this report will be helpful for evaluating the radiation risk for large groups of people with various physiques.

Organ dose conversion coefficients on an ICRP-based Chinese adult male voxel model from idealized external photons exposures

2009 ◽  
Vol 54 (21) ◽  
pp. 6645-6673 ◽  
Author(s):  
Liye Liu ◽  
Zhi Zeng ◽  
Junli Li ◽  
Rui Qiu ◽  
Binquan Zhang ◽  
...  
Keyword(s):  
Adult Male ◽  
Organ Dose ◽  
Chinese Adult ◽  
Voxel Model ◽  
Conversion Coefficients

scholarly journals Organ dose conversion coefficients in CT scans for Korean adult males and females

2021 ◽  
Author(s):  
Choonsik Lee ◽  
Tristan Won ◽  
Yeon Soo Yeom ◽  
Keith Griffin ◽  
Choonik Lee ◽  
...  
Keyword(s):  
Organ Dose ◽  
Ct Scans ◽  
Adult Males ◽  
Conversion Coefficients ◽  
Korean Adult ◽  
Males And Females

Characterization and prevalence of obesity among normal weight college students

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Kara C. Anderson ◽  
Katie R. Hirsch ◽  
Austin M. Peterjohn ◽  
Malia N.M. Blue ◽  
Alexis A. Pihoker ◽  
...  
Keyword(s):  
College Students ◽  
Body Fat ◽  
Fat Mass ◽  
Vigorous Physical Activity ◽  
Normal Weight ◽  
High Density ◽  
High Density Lipoproteins ◽  
Cardiometabolic Health ◽  
Body Fat Percentage ◽  
Fat Percentage

AbstractNormal weight obesity (NWO) describes individuals who have a normal weight body mass index (BMI), but have an unhealthy amount of body fat. Based on the life-long habits that develop during college, exploring NWO among a college-aged population may be essential in identifying and preventing obesity that develops in early adulthood. This study aimed to characterize NWO among young adults with normal weight BMI. 94 college students (Mean ± SD: Age: 19.6 ± 1.5 yrs; BMI: 21.9 ± 1.8 kg/m2) enrolled during the Fall semester (Aug-Oct) were assessed for body composition by dual energy X-ray absorptiometry to determine body fat percentage, fat mass, lean mass and trunk fat; lifestyle habits were characterized from validated questionnaires. Mean arterial pressure and metabolic biomarkers [total cholesterol, high density lipoproteins, non-high density lipoproteins, and glucose] were evaluated for cardiometabolic health. NWO was defined using data from the National Health and Nutrition Examination Survey (NHANES) for body fat percentage. Data was analyzed by group (NWO vs NWL) and sex. with independent t-tests to investigate continuous data, and chi-square test of independence for categorical data. Rates of NWO for the total sample were 13.8%. Males (n=30) had a higher rate of NWO (26.7%) compared to females (n=64; 7.8%). NWO individuals had higher fat mass (p=0.024), trunk fat (p<0.001), and larger waist to hip ratio (p<0.001) than normal weight lean. NWO also engaged in less vigorous physical activity (p=0.043). The occurrence of NWO among otherwise healthy college students is evident. Identification of these individuals may be an effective component for obesity prevention and treatment. Determining feasible methods to measure body fat in this population is essential, as BMI may mask obesity in a young adult population.

scholarly journals Maximal muscle strength and body composition are associated with bone mineral density in chinese adult males

Medicine ◽  
2020 ◽  
Vol 99 (6) ◽  
pp. e19050 ◽  
Author(s):  
Fei Chen ◽  
Qi Su ◽  
Yulan Tu ◽  
Jun Zhang ◽  
Xinji Chen ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Muscle Strength ◽  
Bone Mineral ◽  
Adult Males ◽  
Mineral Density ◽  
Chinese Adult ◽  
Maximal Muscle Strength

Organ dose conversion coefficients based on a voxel mouse model and MCNP code for external photon irradiation

2011 ◽  
Vol 148 (1) ◽  
pp. 9-19 ◽  
Author(s):  
X. Zhang ◽  
X. Xie ◽  
J. Cheng ◽  
J. Ning ◽  
Y. Yuan ◽  
...  
Keyword(s):  
Mouse Model ◽  
Organ Dose ◽  
Mcnp Code ◽  
Photon Irradiation ◽  
Conversion Coefficients

scholarly journals The reproducibility of subjective appetite scores

1995 ◽  
Vol 73 (4) ◽  
pp. 517-530 ◽  
Author(s):  
Anne Raben ◽  
ANNA TAGLIABUE ◽  
Arne Astrup
Keyword(s):  
Visual Analogue Scale ◽  
Food Consumption ◽  
Analogue Scale ◽  
Prior Experience ◽  
Random Noise ◽  
Normal Weight ◽  
Vas Scores ◽  
The Mean ◽  
The Difference ◽  
Mean Differences

Although subjective appetite scores are widely used, studies on the reproducibility of this method are scarce. In the present study nine healthy, normal weight, young men recorded their subjective appetite sensations before and during 5 h after two different test meals A and B. The subjects tested each meal twice and in randomized order. Visual analogue scale (VAS) scores, 10 cm in length, were used to assess hunger, satiety, fullness, prospective food consumption and palatability of the meals. Plasma glucose and lactate concentrations were determined concomitantly. The repeatability was investigated for fasting values, Δ-mean 5 h and mean 5 h values, Δ-peak/nadir and peak/nadir values. Although the profiles of the postprandial responses were similar, the coefficients of repeatability (CR = 2SD) on the mean differences were large, ranging from 2·86 to 5.24 cm for fasting scores, 1·36 to 1·88 cm for mean scores, 2·98 to 5·42 cm for Δ-mean scores, and 3·16 to 6·44 cm for peak and Δ-peak scores. For palatability ratings the CK values varied more, ranging from 2·38 (taste) to 8·70 cm (aftertaste). Part of the difference in satiety ratings could be explained by the differences in palatability ratings. However, the low reproducibility may also be caused by a conditioned satiation or hunger due to the subjects' prior experience of the meals and therefore not just be a reflection of random noise. It is likely, however, that the variation in appetite ratings is due both to methodological day-to-day variation and to biological day-to-day variation in subjective appetite sensations.

scholarly journals Enhancer of rudimentaryp1, e(r)p1, a highly conserved enhancer of the rudimentary gene.

Genetics ◽  
1994 ◽  
Vol 138 (4) ◽  
pp. 1163-1170 ◽  
Author(s):  
E Wojcik ◽  
A M Murphy ◽  
H Fares ◽  
K Dang-Vu ◽  
S I Tsubota
Keyword(s):  
Amino Acid Sequences ◽  
Drosophila Virilis ◽  
P Element ◽  
R Gene ◽  
Adult Males ◽  
Males And Females ◽  
Polyadenylation Sites ◽  
The Difference ◽  
Polyadenylation Signals ◽  
Untranslated Leader Region

Abstract A hybrid dysgenesis-induced mutation, enhancer of rudimentaryp1 (e(r)p1), is a recessive enhancer of a weak rudimentary mutant phenotype in Drosophila melanogaster. The e(r) gene was cloned using P element tagging and localized to region 8B on the X chromosome. It encodes a 1.0-kb and a 1.2-kb transcript. The 1.0-kb transcript is present in both adult males and females, while the 1.2-kb transcript is predominantly found in females. The difference in the lengths of the two e(r) transcripts is caused by two different polyadenylation sites spaced 228 bp apart. The amounts of both of these transcripts are drastically reduced in the e(r)p1 mutant. The P element in e(r)p1 is inserted in the 5'-untranslated leader region near the start of transcription. It may be producing its effect by suppressing transcription and/or by providing transcription termination and polyadenylation signals. The putative e(r) protein is 104 amino acids in length and bears no striking resemblance to protein sequences in GenBank or PIR. While its biochemical function is unknown at this time, sequence analysis indicates that the e(r) protein is highly conserved and, presumably, functionally very important. The amino acid sequences of the D. melanogaster and the Drosophila virilis proteins are 95% identical.

scholarly journals 520 Weight-based vs. BSA-based Fluid Resuscitation Predictions in Pediatric Burn Patients

2021 ◽  
Vol 42 (Supplement_1) ◽  
pp. S107-S107
Author(s):  
Jan V Stevens ◽  
Nina Prieto ◽  
Elika Ridelman ◽  
Justin D Klein ◽  
Christina M Shanti
Keyword(s):  
Surface Area ◽  
Fluid Resuscitation ◽  
Normal Weight ◽  
Overweight Children ◽  
Obese Children ◽  
Post Injury ◽  
Pediatric Burns ◽  
The Difference ◽  
Parkland Formula ◽  
Total Fluid

Abstract Introduction Current practice for major pediatric burns includes fluid resuscitation using formulas that estimate fluid requirements based on weight and/or body surface area (BSA) along with percent total burn surface area (TBSA). Adult studies have shown that these formulas can cause fluid overload in obese patients and increase risk of complications. These findings have not been validated in pediatric patients. This study aims to evaluate whether a weight-based resuscitation formula increases the risk of complications in obese children following burn injuries and compares fluid estimates to those that incorporate BSA. Methods A retrospective review was conducted on 110 children (≤ 18 years old) admitted to an ABA-verified urban pediatric burn center from October 2008 to May 2020. Patients had ≥15% TBSA, were resuscitated with the weight-based Parkland formula, and had fluids titrated to urine output every two hours (1 ml/kg/hr if ≤ 30kg; 0.5 ml/kg/hr if &gt; 30kg). Demographics, burn type, and TBSA were collected on admission. BSA-based Galveston and BSA-incorporated Cincinnati formula resuscitation predictions were also calculated. Output and input volumes were collected at 8h and 24h post-injury. Complications were collected throughout the hospital stay. Patients were classified into CDC-defined weight groups based on percentile ranges. Statistical analysis was conducted using SPSS Statistics version 10.0. Results This study included 11 underweight, 60 normal weight, 18 overweight, and 21 obese children. Our patients had a mean age-based weight CDC percentile of 62.2%, and mean TBSA of 25.4%. Predicted resuscitation volumes increased as CDC percentile increased for all three formulas (p=0.033, 0.092, 0.038), however there were no significant differences between overweight and obese children. Total fluid administered was higher as CDC percentile increased (p=0.023). However, overweight children received more total fluid than obese children. The difference between total fluids given and Galveston predicted resuscitation volumes were significant across all groups (p=0.042); however, the difference using the Parkland and Cincinnati formulas were not statistically significant. There were more children in the normal weight group who developed complications compared to other groups, but these findings were not significant. Conclusions The Parkland formula tended to underpredict fluid needs in the underweight, normal weight, and overweight children, and it overpredicted fluid needs for the obese. Further research is needed to determine the value of weight-based vs BSA-based or incorporated formulas in terms of their risk of complications.

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