Hoarding Disorder

Author(s):  
Randy O. Frost ◽  
Lucy Graves ◽  
Elizabeth Atkins

Hoarding Disorder (HD), new in DSM-5, is remarkably prevalent, affecting 2% to 5% of the population. Hoarding symptoms were long considered an aspect of OCD, but it has been increasingly recognized that they differ, phenomenologically and epidemiologically; the new DSM-5 diagnosis formalizes this recognition. HD is a complex disorder consisting of problems with attachments to possessions that lead to difficulty discarding and organizing them. Together, these features lead to severely cluttered living spaces that can pose serious health and safety threats. The vast majority of those with HD acquire excessively, mostly through buying or collecting things that others have discarded. Hoarding behaviors appear early in life and typically get progressively worse over the life span. Cognitive behavioral therapy specifically designed to treat hoarding has been shown to be effective, though many still suffer from symptoms after treatment. Several medications have shown promise, but no controlled clinical trials have been conducted.

2015 ◽  
Vol 32 (3) ◽  
pp. 158-166 ◽  
Author(s):  
David F. Tolin ◽  
Randy O. Frost ◽  
Gail Steketee ◽  
Jordana Muroff

Author(s):  
Phillip Tully ◽  
Suzanne Cosh ◽  
Bethany Wootton

Hoarding disorder (HD) is characterized by an accumulation of possessions due to excessive acquisition of, or difficulty discarding possessions. Evidence demonstrates an increased cardiovascular response in patients with HD. Cognitive-behavioral therapy modifications are described for HD patients with heart failure to compensate for fatigability, syncope and falls risk.


2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Jeremy E. Chester ◽  
Mazhgan Rowneki ◽  
William Van Doren ◽  
Drew A. Helmer

Abstract The Persian Gulf War of 1990 to 1991 involved the deployment of nearly 700,000 American troops to the Middle East. Deployment-related exposures to toxic substances such as pesticides, nerve agents, pyridostigmine bromide (PB), smoke from burning oil wells, and petrochemicals may have contributed to medical illness in as many as 250,000 of those American troops. The cluster of chronic symptoms, now referred to as Gulf War Illness (GWI), has been studied by many researchers over the past two decades. Although over $500 million has been spent on GWI research, to date, no cures or condition-specific treatments have been discovered, and the exact pathophysiology remains elusive. Using the 2007 National Institute of Health (NIH) Roadmap for Medical Research model as a reference framework, we reviewed studies of interventions involving GWI patients to assess the progress of treatment-related GWI research. All GWI clinical trial studies reviewed involved investigations of existing interventions that have shown efficacy in other diseases with analogous symptoms. After reviewing the published and ongoing registered clinical trials for cognitive-behavioral therapy, exercise therapy, acupuncture, coenzyme Q10, mifepristone, and carnosine in GWI patients, we identified only four treatments (cognitive-behavioral therapy, exercise therapy, CoQ10, and mifepristone) that have progressed beyond a phase II trial. We conclude that progress in the scientific study of therapies for GWI has not followed the NIH Roadmap for Medical Research model. Establishment of a standard case definition, prioritized GWI research funding for the characterization of the pathophysiology of the condition, and rapid replication and adaptation of early phase, single site clinical trials could substantially advance research progress and treatment discovery for this condition.


2021 ◽  
Vol 7 (1) ◽  
pp. 1-10
Author(s):  
Tarrinni Inastyarikusuma

Pendahuluan: Obsessive-compulsive disorder (OCD) merupakan gangguan neuropsikiatri yang menyulitkan, menyita waktu, atau mengganggu secara substantial. OCD pediatrik terjadi pada 1-2% anak-anak dan remaja. Hal tersebut ditandai dengan adanya obsesi dan kompulsi berulang yang menimbulkan bahaya dan mengganggu kehidupan sehari-hari. OCD pediatrik dikaitkan dengan peningkatan risiko gangguan psikiatri lainnya di masa dewasa. Pada OCD onset anak, anak laki-laki lebih sering terkena OCD dibanding anak perempuan (rasio laki-laki:perempuan, 2:1 hingga 3:1), sedangkan rasio jenis kelamin bergeser hingga masa setelah pubertas dengan perbandingan laki- laki:perempuan 1: 1,4. Pembahasan: Terdapat beberapa teori yang dinyatakan sebagai penyebab OCD, yaitu disfungsi ganglia basalis, kelainan neurotransmitter, dan disfungsi neuroimun. Penilaian gejala OCD dapat dilakukan menggunakan berbagai alat, tetapi alat yang lebih sering digunakan adalah SOCS dan untuk diagnosis tetap berpedoman pada ICD-10 dan DSM- 5. Kesimpulan: Menurut terapi berbasis bukti, pengobatan pada OCD pediatrik yang terbaik adalah dengan cognitive behavioral therapy (CBT) dan SRI/SSRI. Kata Kunci: cognitive behavioral therapy, obsessive-compulsive disorder, pediatrik, remaja


F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 638 ◽  
Author(s):  
Douglas Berger

While double-blinding is a crucial aspect of study design in an interventional clinical trial of medication for a disorder with subjective endpoints such as major depressive disorder, psychotherapy clinical trials, particularly cognitive-behavioral therapy trials, cannot be double-blinded. This paper highlights the evidence-based medicine problem of double-blinding in the outcome research of a psychotherapy and opines that psychotherapy clinical trials should be called, “partially-controlled clinical data” because they are not double-blinded. The implications for practice are, 1. For practitioners to be clear with patients the level of rigor to which interventions have been studied, 2. For authors of psychotherapy outcome studies to be clear that the problem in the inability to blind a psychotherapy trial severely restricts the validity of any conclusions that can be drawn, and 3. To petition National Health Insurance plans to use caution in approving interventions studied without double-blinded confirmatory trials as they may lead patients to avoid other treatments shown to be effective in double-blinded trials.


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