Dementing Illnesses

Author(s):  
Linda M. Selwa ◽  
Douglas J. Gelb

Dementia is defined as an acquired, persistent decline of intellectual function that causes impaired performance of daily activities, without clouding of the sensorium or underlying psychiatric disease. The decline must involve at least two of the following domains: (a) ability to learn and remember new information, (b) reasoning and judgment, (c) visuospatial perception, (d) language function, and (e) personality and behavior. Patients who have experienced an episode of brain dysfunction from a wide variety of causes may be left with significantly impaired cognitive function that subsequently remains stable or improves. These nonprogressive dementias do not present the same diagnostic or management issues as the progressive dementias.

2017 ◽  
Vol 637 ◽  
pp. 182-187 ◽  
Author(s):  
Shuangling Xiu ◽  
Zheng Zheng ◽  
Shaochen Guan ◽  
Jin Zhang ◽  
Jinghong Ma ◽  
...  

2014 ◽  
Vol 12 ◽  
pp. S63-S64
Author(s):  
Dilan Pathmajothy ◽  
James Bowyer ◽  
Thomas Knapper ◽  
David Clarke

2000 ◽  
Vol 72 (3) ◽  
pp. 762-769 ◽  
Author(s):  
Marieke WJ Louwman ◽  
Marijke van Dusseldorp ◽  
Fons JR van de Vijver ◽  
Chris MG Thomas ◽  
Jørn Schneede ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marta Waliszewska-Prosół ◽  
Joanna Bladowska ◽  
Sławomir Budrewicz ◽  
Marek Sąsiadek ◽  
Edyta Dziadkowiak ◽  
...  

AbstractThyroid dysfunction is very often accompanied by cognitive and affective disorders. The frequency of these disorders in patients with compensated Hashimoto’s thyroiditis (HT) is unknown. The aim of the present study was to evaluate brain dysfunction in euthyroid HT patients by means of event-related potentials (ERP) and magnetic resonance spectroscopy (MRS) and to correlate it with cognitive function. 68 patients with HT (59 female, 9 male) and 45 healthy controls were included in the study. All the patients underwent ERP including an analysis of N200 and P300 response parameters. MRS voxels were located in the posterior cingulate gyrus (PCG) and the left parietal white matter (PWM). The NAA/Cr, mI/Cr, and Cho/Cr ratios were analysed. The ERP parameters, MRS metabolite ratios and hormonal concentrations (TSH, fT3, fT4) as well as TGAb and TPOAb titer were also correlated. There was a significant prolongation of the latencies of N200 and P300 potentials and a significant decrease of P300 amplitude in HT patients than in the control group. There was a significant positive correlation between the mI/Cr ratio in the PCG area and P300 latencies. NAA/Cr ratio in the PCG region showed significant negative correlations with all N200 latencies. The results may suggest brain dysfunction in neurologically asymptomatic HT patients. ERPs undergo significant changes in patients with HT and may, in combination with MRS, constitute an important element in the recognition and monitoring of cognitive functions in this group of patients.


2012 ◽  
Vol 322 (1-2) ◽  
pp. 20-24 ◽  
Author(s):  
Brandon G. Rocque ◽  
Daren Jackson ◽  
Tomy Varghese ◽  
Bruce Hermann ◽  
Matthew McCormick ◽  
...  

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