Liver procedures

2021 ◽  
pp. 695-708
Author(s):  
Alwyn Kotze ◽  
Nilmini Manawaduge
Keyword(s):  
Liver Transplantation ◽  
Hepatic Resection ◽  
Anaesthetic Management

This chapter discusses the anaesthetic management of liver procedures. It begins with a description of the anaesthetic management of acute oesophageal bleeding, transjugular intrahepatic porto-systemic shunt procedures, liver transplantation and hepatic resection.

Liver transplantation and resection

2018 ◽  
Author(s):  
Mark Bellamy
Keyword(s):  
Liver Transplantation ◽  
Hepatic Resection ◽  
Surgical Procedures ◽  
Anaesthetic Management ◽  
Hepatic Surgery

This chapter discusses the anaesthetic management of liver transplantation and resection. It begins with a description of the general principles of the anaesthetic management of hepatic surgery, and it covers the surgical procedures of liver transplantation and hepatic resection.

scholarly journals The Impact of Time Interval between Hepatic Resection and Liver Transplantation on Clinical Outcome in Patients with Hepatocellular Carcinoma

Cancers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 2398
Author(s):  
Matteo Serenari ◽  
Enrico Prosperi ◽  
Marc-Antoine Allard ◽  
Michele Paterno ◽  
Nicolas Golse ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Hepatic Resection ◽  
Primary Outcome ◽  
Polynomial Regression ◽  
Secondary Outcome ◽  
Time Interval ◽  
Comprehensive Complication Index ◽  
Fractional Polynomial ◽  
The Impact

Hepatic resection (HR) for hepatocellular carcinoma (HCC) may require secondary liver transplantation (SLT). However, a previous HR is supposed to worsen post-SLT outcomes. Data of patients treated by SLT between 2000 and 2018 at two tertiary referral centers were analyzed. The primary outcome of the study was to analyze the impact of HR on post-LT complications. A Comprehensive Complication Index ≥ 29.6 was chosen as cutoff. The secondary outcome was HCC-related death by means of competing-risk regression analysis. In the study period, 140 patients were included. Patients were transplanted in a median of 23 months after HR (IQR 14–41). Among all the features analyzed regarding the prior HR, only time interval between HR and SLT (time HR-SLT) was an independent predictor of severe complications after LT (OR = 0.98, p < 0.001). According to fractional polynomial regression, the probability of severe complications increased up to 15 months after HR (43%), then slowly decreased over time (OR = 0.88, p < 0.001). There was no significant association between HCC-related death and time HR-SLT at the multivariable competing risks regression model (SHR, 1.06; 95% CI: 0.69–1.62, p = 0.796). This study showed that time HR-SLT was key in predicting complications after LT, without affecting HCC-related death.

scholarly journals Long-Term Outcomes of Hepatic Resection versus Living Donor Liver Transplantation for Hepatocellular Carcinoma: A Propensity Score-Matching Study

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Toshimi Kaido ◽  
Satoshi Morita ◽  
Sachiko Tanaka ◽  
Kohei Ogawa ◽  
Akira Mori ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Propensity Score ◽  
Hepatic Resection ◽  
Propensity Score Matching ◽  
Odds Ratio ◽  
Living Donor ◽  
Survival Rates ◽  
Controlled Study ◽  
Recurrence Rates

Hepatic resection (HR) and liver transplantation (LT) are surgical treatment options for hepatocellular carcinoma (HCC). However, it is clinically impossible to perform a randomized, controlled study to determine the usefulness of these treatments. The present study compared survival rates and recurrence rates of HR versus living donor LT (LDLT) for HCC by using the propensity score method. Between January 1999 and August 2012, 936 patients (732 HR, 204 LDLT) underwent surgical therapy for HCC in our center. Using the propensity score matching, 80 well-balanced patients were defined. The 1- and 5-year overall survival rates were 90% and 53% in the HR group and 82% and 63% in the LT group, respectively. They were not significantly different between the two groups. The odds ratio estimated using the propensity score matching analysis was 0.842 (P=0.613). The 1- and 5-year recurrence rates were significantly lower in the LT group (9% and 21%) than in the HR group (43% and 74%) (P<0.001), and the odds ratio was 0.214 (P=0.001). In conclusion, HR should be considered a valid alternative to LDLT taking into consideration the risk for the living donor based on the results of this propensity score-matching study.

MODIFICATION OF SOLUBLE STEM CELL FACTOR (S-SCF) LEVELS DURING LIVER TRANSPLANTATION AND HEPATIC RESECTION

2004 ◽  
Vol 78 ◽  
pp. 730-731
Author(s):  
U Baccarani ◽  
G De Stasio ◽  
G L. Adani ◽  
M Sainz ◽  
D Lorenzin ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Stem Cell ◽  
Hepatic Resection ◽  
Stem Cell Factor

scholarly journals Accuracy of computerized tomography in determining hepatic tumor size in patients receiving liver transplantation or resection.

1984 ◽  
Vol 2 (6) ◽  
pp. 637-642 ◽  
Author(s):  
R Mittal ◽  
C Kowal ◽  
T Starzl ◽  
D Van Thiel ◽  
K Bron ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatic Resection ◽  
Computerized Tomography ◽  
Liver Tumors ◽  
Imaging Techniques ◽  
Hepatic Metastases ◽  
Response To Treatment ◽  
Preoperative Ct ◽  
Malignant Liver ◽  
The Impact

Computerized tomography (CT) of liver is used in oncologic practice for staging tumors, evaluating response to treatment, and screening patients for hepatic resection. Because of the impact of CT liver scan on major treatment decisions, it is important to assess its accuracy. Patients undergoing liver transplantation or resection provide a unique opportunity to test the accuracy of hepatic-imaging techniques by comparison of findings of preoperative CT scan with those at gross pathologic examination of resected specimens. Forty-one patients who had partial hepatic resection (34 patients) or liver transplantation (eight patients) for malignant (30 patients) or benign (11 patients) tumors were evaluable. Eight (47%) of 17 patients with primary malignant liver tumors, four (31%) of 13 patients with metastatic liver tumors, and two (20%) of 10 patients with benign liver tumors had tumor nodules in resected specimens that were not apparent on preoperative CT studies. These nodules varied in size from 0.1 to 1.6 cm. While 11 of 14 of these nodules were less than 1.0 cm, three of 14 were greater than 1.0 cm. These results suggest that conventional CT alone may be insufficient to accurately determine the presence or absence of liver metastases, extent of liver involvement, or response of hepatic metastases to treatment.

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