2520. Epidemiology, Clinical Manifestations, and Outcomes of the 2017–2018 Influenza Season Among Hospitalized Patients at a Tertiary Care Center

Background: Influenza causes a high burden of disease in the United States, with an estimate of 960,000 hospitalizations in the 2017–2018 flu season. Traditional flu diagnostic polymerase chain reaction (PCR) tests have a longer (24 hours or more) turnaround time that may lead to an increase in unnecessary inpatient admissions during peak influenza season. A new point-of-care rapid PCR assays, Xpert Flu, is an FDA-approved PCR test that has a significant decrease in turnaround time (2 hours). The present study sought to understand the impact of implementing a new Xpert Flu test on the rate of inpatient admissions. Methods: A retrospective study was conducted to compare rates of inpatient admissions in patients tested with traditional flu PCR during the 2017–2018 flu season and the rapid flu PCR during the 2018–2019 flu season in a tertiary-care center in greater Detroit area. The center has 1 pediatric hospital (hospital A) and 3 adult hospitals (hospital B, C, D). Patients with influenza-like illness who presented to all 4 hospitals during 2 consecutive influenza seasons were analyzed. Results: In total, 20,923 patients were tested with either the rapid flu PCR or the traditional flu PCR. Among these, 14,124 patients (67.2%) were discharged from the emergency department and 6,844 (32.7%) were admitted. There was a significant decrease in inpatient admissions in the traditional flu PCR group compared to the rapid flu PCR group across all hospitals (49.56% vs 26.6% respectively; P < .001). As expected, a significant proportion of influenza testing was performed in the pediatric hospital, 10,513 (50.2%). A greater reduction (30% decrease in the rapid flu PCR group compared to the traditional flu PCR group) was observed in inpatient admissions in the pediatric hospital (Table 1) Conclusions: Rapid molecular influenza testing can significantly decrease inpatient admissions in a busy tertiary-care hospital, which can indirectly lead to improved patient quality with easy bed availability and less time spent in a private room with droplet precautions. Last but not the least, this testing method can certainly lead to lower healthcare costs.Funding: NoneDisclosures: None

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Ocular Involvement in Hospitalized Patients with Candidemia: Analysis at a Boston Tertiary Care Center

Ocular Immunology and Inflammation ◽

10.3109/09273948.2011.646383 ◽

2012 ◽

Vol 20 (2) ◽

pp. 100-103 ◽

Cited By ~ 15

Author(s):

Nancy Huynh ◽

Han-Ying Peggy Chang ◽

Sheila Borboli-Gerogiannis

Keyword(s):

Care Center ◽

Tertiary Care ◽

Hospitalized Patients ◽

Ocular Involvement ◽

Tertiary Care Center

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Diagnoses of hospitalized patients with skin abnormalities prompting biopsy by consulting dermatologists: A 3‐year review from a tertiary care center

Journal of Cutaneous Pathology ◽

10.1111/cup.13628 ◽

2019 ◽

Vol 47 (4) ◽

pp. 346-356 ◽

Cited By ~ 1

Author(s):

Ariana Ellis ◽

Steven D. Billings ◽

Urmi Khanna ◽

Christine B. Warren ◽

Melissa Piliang ◽

...

Keyword(s):

Care Center ◽

Tertiary Care ◽

Hospitalized Patients ◽

Tertiary Care Center ◽

Skin Abnormalities

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Scrub Typhus with Varied Clinical Presentations

Journal of Pediatric Infectious Diseases ◽

10.1055/s-0037-1605363 ◽

2017 ◽

Vol 13 (04) ◽

pp. 319-322

Author(s):

Susrita Banerjee ◽

Satyabrata Roychowdhuri ◽

Mihir Sarkar

Keyword(s):

Scrub Typhus ◽

Care Center ◽

Tertiary Care ◽

Clinical Manifestations ◽

Case Series ◽

Dengue Shock Syndrome ◽

Tertiary Care Center ◽

Eastern India ◽

Clinical Presentations ◽

Diagnostic Difficulties

AbstractWe present four cases of pediatric scrub typhus from a tertiary care center of eastern India, emphasizing on varied unusual clinical manifestations posing diagnostic difficulties. A low index of suspicion is required to prevent under diagnosis. We report a case series of four patients with scrub typhus having uncommon clinical manifestations (two patients with hemophagocytic lymphohistiocytosis, one patient with myocarditis, and one patient presenting with shock reminiscent of dengue shock syndrome). The response to doxycycline was good, with fever subsiding within 48 to 72 hours of starting the treatment. Three out of four cases completely recovered once appropriate medication was given.

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Dermatology consultations significantly contribute quality to care of hospitalized patients: a prospective study of dermatology inpatient consults at a tertiary care center

International Journal of Dermatology ◽

10.1111/ijd.13327 ◽

2016 ◽

Vol 55 (10) ◽

pp. e547-e551 ◽

Cited By ~ 14

Author(s):

Fabrizio Galimberti ◽

Lauren Guren ◽

Anthony P. Fernandez ◽

Apra Sood

Keyword(s):

Prospective Study ◽

Care Center ◽

Tertiary Care ◽

Hospitalized Patients ◽

Tertiary Care Center ◽

A Prospective Study

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Epidemiological and clinical profile of various plant poisons in a tertiary care center in South Tamilnadu, India

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20193939 ◽

2019 ◽

Vol 7 (9) ◽

pp. 3517

Author(s):

Meena Kumari ◽

Pattu Swarna Latha ◽

Kalyanasundaram .

Keyword(s):

Care Center ◽

Tertiary Care ◽

Clinical Manifestations ◽

Tertiary Care Center ◽

Active Components ◽

Medical College ◽

Suicidal Intention ◽

History Of ◽

Plant Constituents ◽

Plant Poisoning

Background: Plant poisoning is a common scenario in a toxicology unit . Some of the plants contain active components used as medicines. However, some of the plant constituents are poisonous with wide variety of clinical manifestations. Authors aimed to study the pattern of various types of plant poisons and clinical presentations and complications of various plant poisons admitted in our toxicological unit.Methods: A total of 87 patients admitted with history of plant poison ingestion, in toxicological unit of Tirunelveli medical college were studied . It was a retrospective observational study and was done over a period of one year.Results: Out of 87 cases studied, 92%were due to consumption with suicidal intention. Plant poisoning ranks second only to pesticide poisoning . among the plant poisons encountered 66.6% were due to Oleander poison, followed by Datura (8%) and Glory lily(5.7%). Common parts of plant consumed by patients include seeds and plant oils . Vomiting and abdominal pain were the commonest presentations. Encephalopathy, dyselectrolytemia and arrhythmias were the notable complications in our study.Conclusions: Early admission and prompt first aid and monitoring at tertiary care center are key to the reduced mortality. The study throws light on various manifestations, toxic parts and complications of plant poisons.

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