scholarly journals Clinically amyopathic dermatomyositis during the COVID-19 pandemic

2021 ◽  
Vol 2021 (8) ◽  
Author(s):  
Masakazu Kitamura ◽  
Hiroshi Sugimoto
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Oral Prednisolone ◽  
Skin Lesions ◽  
Japanese Woman ◽  
Ground Glass ◽  
Amyopathic Dermatomyositis ◽  
Chest Computed Tomography ◽  
Clinically Amyopathic Dermatomyositis ◽  
Old Japanese

ABSTRACT An 84-year-old Japanese woman presented to our hospital with a month-long dry cough during the coronavirus disease 2019 (COVID-19) pandemic. She also had skin lesions on her fingers from 3 months prior. A chest computed tomography (CT) scan showed bilateral ground- glass opacities with a subpleural distribution, similar to the findings of COVID-19. The results of COVID-19 tests were negative. The titer of the anti-melanoma differentiation-associated gene 5 (MDA5) antibody was elevated. Consequently, we confirmed the diagnosis of clinically amyopathic dermatomyositis (CADM) and then administered oral prednisolone combined with tacrolimus. After the treatment, her symptoms, skin lesions and CT findings were gradually resolved.

scholarly journals Chest CT Imaging Spectrum of Coronavirus Disease 2019 (COVID-19) Pneumonia: A Pictorial Essay

2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Mehdi Khazaei ◽  
Arash Mahdavi ◽  
Zahra Mahboubi-Fooladi ◽  
Yashar Moharamzad ◽  
Reyhaneh Asgari ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Ct Imaging ◽  
Chest Ct ◽  
Ground Glass ◽  
Chest Computed Tomography ◽  
Halo Sign ◽  
Pictorial Review ◽  
Pictorial Essay

: Various manifestations may appear in chest computed tomography (CT) scan of patients with coronavirus disease 2019 (COVID-19). In this pictorial review, we present chest CT manifestations of 14 patients with laboratory-confirmed COVID-19 disease and various manifestations including ground-glass and consolidative opacities, reticular opacities, halo sign, and other findings.

scholarly journals Pure ground-glass opacity on chest computed tomography: predictive factors for invasive adenocarcinoma

2016 ◽  
Vol 8 (7) ◽  
pp. 1561-1570 ◽  
Author(s):  
Youngkyu Moon ◽  
Sook Whan Sung ◽  
Kyo Young Lee ◽  
Sung Bo Sim ◽  
Jae Kil Park
Keyword(s):  
Computed Tomography ◽  
Predictive Factors ◽  
Ground Glass Opacity ◽  
Ground Glass ◽  
Invasive Adenocarcinoma ◽  
Chest Computed Tomography

scholarly journals The utility of chest computed tomography (CT) and RT-PCR screening of asymptomatic patients for SARS-CoV-2 prior to semiurgent or urgent hospital procedures

2020 ◽  
Vol 41 (12) ◽  
pp. 1375-1377 ◽  
Author(s):  
Aditya S. Shah ◽  
Lara A. Walkoff ◽  
Ronald S. Kuzo ◽  
Matthew R. Callstrom ◽  
Michael J. Brown ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Tertiary Care ◽  
Case Series ◽  
Chest Ct ◽  
Study Cohort ◽  
Rt Pcr ◽  
Chest Computed Tomography ◽  
Tertiary Care Medical Center ◽  
Asymptomatic Patients

AbstractObjective:Presently, evidence guiding clinicians on the optimal approach to safely screen patients for coronavirus disease 2019 (COVID-19) to a nonemergent hospital procedure is scarce. In this report, we describe our experience in screening for SARS-CoV-2 prior to semiurgent and urgent hospital procedures.Design:Retrospective case series.Setting:A single tertiary-care medical center.Participants:Our study cohort included patients ≥18 years of age who had semiurgent or urgent hospital procedures or surgeries.Methods:Overall, 625 patients were screened for SARS-CoV-2 using a combination of phone questionnaire (7 days prior to the anticipated procedure), RT-PCR and chest computed tomography (CT) between March 1, 2020, and April 30, 2020.Results:Of the 625 patients, 520 scans (83.2%) were interpreted as normal; 1 (0.16%) had typical features of COVID-19; 18 scans (2.88%) had indeterminate features of COVID-19; and 86 (13.76%) had atypical features of COVID-19. In total, 640 RT-PCRs were performed, with 1 positive result (0.15%) in a patient with a CT scan that yielded an atypical finding. Of the 18 patients with chest CTs categorized as indeterminate, 5 underwent repeat negative RT-PCR nasopharyngeal swab 1 week after their initial swab. Also, 1 patient with a chest CT categorized as typical had a follow-up repeat negative RT-PCR, indicating that the chest CT was likely a false positive. After surgery, none of the patients developed signs or symptoms suspicious of COVID-19 that would indicate the need for a repeated RT-PCR or CT scan.Conclusion:In our experience, chest CT scanning did not prove provide valuable information in detecting asymptomatic cases of SARS-CoV-2 (COVID-19) in our low-prevalence population.

scholarly journals Bronchial Leech Infestation in a 15-Year-Old Female

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Mohammad Ashkan Moslehi ◽  
Mohammad Hadi Imanieh ◽  
Ali Adib
Keyword(s):  
Computed Tomography ◽  
Foreign Body ◽  
Young Children ◽  
Lower Lobe ◽  
Foreign Body Aspiration ◽  
Ground Glass ◽  
Chest Computed Tomography ◽  
X Ray ◽  
Chest X Ray ◽  
The Right

Foreign body aspiration (FBA) is a common incidence in young children. Leeches are rarely reported as FBA at any age. This study describes a 15-year-old female who presented with hemoptysis, hematemesis, coughs, melena, and anemia seven months prior to admission. Chest X-ray showed a round hyperdensity in the right lower lobe. A chest computed tomography (CT) demonstrated an area of consolidation and surrounding ground glass opacities in the right lower lobe. Hematological investigations revealed anemia. Finally, bronchoscopy was performed and a 5 cm leech was found within the rightB7-8bronchus and removed by forceps and a Dormia basket.

Drug Hypersensitivity Syndrome Caused by Minocycline

2006 ◽  
Vol 10 (3) ◽  
pp. 131-135 ◽  
Author(s):  
Daisuke Tsuruta ◽  
Yukiko Someda ◽  
Junko Sowa ◽  
Hiromi Kobayashi ◽  
Masamitsu Ishii
Keyword(s):  
Drug Hypersensitivity ◽  
Human Herpesvirus ◽  
Oral Prednisolone ◽  
Liver Function Tests ◽  
Hypersensitivity Syndrome ◽  
Skin Lesions ◽  
Japanese Woman ◽  
Barr Virus ◽  
Epstein Barr ◽  
Drug Hypersensitivity Syndrome

Background: Minocycline is a commonly prescribed drug for the treatment of acne. Its use is generally not associated with systemic side effects. Objective: To describe a case of minocycline-induced drug hypersensitivity syndrome in a 20-year-old Japanese woman. Methods and Results: Following 2 months of minocycline treatment, the patient developed skin lesions composed of exudative maculopapules, purpuratous macules, and target-like, erythema multiforme-like plaques over most of her body. In addition, she had fever, abnormal liver function tests, eosinophilia, and atypical lymphocytosis. Laboratory tests indicated no elevation of antibody titers against cytomegalovirus, Epstein-Barr virus, and human herpesvirus 6. Her ongoing exposure to minocycline was stopped, and treatment with oral prednisolone was begun. Her signs, symptoms, and laboratory abnormalities then began to resolve. Subsequently, the syndrome was observed to return briefly in response to an oral challenge with minocycline. Conclusions: Minocycline is able to elicit a drug hypersensitivity syndrome that can resemble infectious mononucleosis. This drug reaction can be treated effectively by cessation of exposure to this drug and steroid therapy.

Elderly case of non-mucinous bronchioloalveolar carcinoma showing diffuse ground-glass changes on chest computed tomography

2003 ◽  
Vol 3 (3) ◽  
pp. 164-167
Author(s):  
Masayuki Kikawada ◽  
Kentarou Hirao ◽  
Takeshi Shimizu ◽  
Masanori Uno ◽  
Toshihiko Iwamoto ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ground Glass ◽  
Bronchioloalveolar Carcinoma ◽  
Chest Computed Tomography

scholarly journals A Case of Amyopathic Dermatomyositis with Pneumomediastinum and Subcutaneous Emphysema

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Aslıhan Gürün Kaya ◽  
Aydın Çiledağ ◽  
Orhan Küçükşahin ◽  
Özlem Özdemir Kumbasar ◽  
Çetin Atasoy
Keyword(s):  
Computed Tomography ◽  
Subcutaneous Emphysema ◽  
Poor Prognosis ◽  
Immunosuppressive Treatment ◽  
Skin Lesions ◽  
Rare Occurrence ◽  
Amyopathic Dermatomyositis ◽  
Radiological Findings ◽  
Radiological Progression ◽  
Hypoxemic Respiratory Failure

A 34-year-old man was admitted with dyspnea, cough, and fever. Thorax computed tomography revealed ground glass opacities and pneumomediastinum. The patient was diagnosed as amyopathic dermatomyositis due to skin lesions and radiological findings. Despite immunosuppressive treatment clinical deterioration and radiological progression were observed and the patient died because of severe hypoxemic respiratory failure. The patient presented with extremely rare occurrence of pneumomediastinum and subcutaneous emphysema in amyopathic dermatomyositis with a poor prognosis.

scholarly journals Dermoscopic Features of Pigmented Bowen's Disease in a Japanese Female Mimicking Malignant Melanoma

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Takayuki Inoue ◽  
Ken Kobayashi ◽  
Mizuki Sawada ◽  
Sumiko Ishizaki ◽  
Haruo Ito ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Skin Lesions ◽  
Japanese Woman ◽  
Bowen’S Disease ◽  
Seborrheic Keratosis ◽  
Bowen's Disease ◽  
Pathologic Features ◽  
Old Japanese ◽  
History Of ◽  
Pigmented Skin Lesions

Various structures have been reported for dermoscopic features of pigmented Bowen's disease (BD), which could be a mimic of various pigmented skin lesions. A 79-year-old Japanese woman presented with a 3-year history of brown-black macule on her right upper arm without symptom. Dermoscopic examination demonstrated irregular flossy streaks, irregular brown dots/globules, blue-whitish regression structures, and overlaying whitish scaly areas. We suspected pigmented skin lesions including seborrheic keratosis, pigmented eccrine poroma, and malignant melanoma and excised completely with a 5 mm margin. Histopathological features were consistent with a diagnosis of pigmented BD. Although similar dermoscopic features might be revealed in pigmented skin lesions and it may occasionally be difficult to distinguish between pigmented BD and other pigmented skin lesions, dermoscopy would be useful in speculating pathologic features of pigmented BD.

scholarly journals Specificity of chest computed tomography in COVID-19-associated pneumonia: a retrospective study

2021 ◽  
Vol 49 (1) ◽  
pp. 1-10
Author(s):  
T. A. Korb ◽  
P. V. Gavrilov ◽  
V. Yu. Chernina ◽  
I. A. Blokhin ◽  
O. O. Aleshina ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Coefficient Of Variation ◽  
Information Service ◽  
Chest Ct ◽  
Primary Study ◽  
Chest Computed Tomography ◽  
Moscow City ◽  
Attending Physician ◽  
Chest Ct Scan

Aim: To assess the specificity of COVID-19- associated pneumonia detection by radiologists using a chest CT scan.Materials and methods: From mid-February to early March 2020, 65  patients have been retrospectively selected from the Moscow City Clinical Hospital database; all of them had been treated in an inpatient facility with a  verified diagnosis of COVID-19. In addition, 75  patients from the Unified Radiological Information Service have been randomly selected. In December 2019, these outpatients had been sent by an attending physician for a  chest CT scan with suspected pneumonia. The imaging studies showed non-specific inflammation signs in the lungs. All 140  scans were analyzed by seven radiologists from different Russian cities, who independently categorized each study as “COVID-19” or “Other pneumonia”.Results: Chest computed tomography had a  92%  specificity in the differential diagnosis of COVID-19-associated pneumonia, and its specificity in the general population is expected to be at least 80% with a high probability. The inter-rater variability was low (coefficient of variation for specificity 12.6%). The sensitivity in our study was 76.2%, and the coefficient of variation for sensitivity 23.5%. These findings are generally consistent with other studies. The primary study limitation is the absence of a sample with confirmed pneumonia caused by other viruses.Conclusion: Chest CT is highly specific for the detection of COVID-19-associated pneumonia.

scholarly journals Probable vertical transmission identified within six hours of life

2020 ◽  
Vol 66 (12) ◽  
pp. 1621-1624
Author(s):  
Fabrício Silva Pessoa ◽  
Marynéa Silva do Vale ◽  
Patrícia Franco Marques ◽  
Susana da Silva Figueira ◽  
Izabel Athayde da Silva Cruz Salgado ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cesarean Section ◽  
Vertical Transmission ◽  
Pregnant Patient ◽  
Ambient Air ◽  
Ground Glass ◽  
Rt Pcr ◽  
Chest Computed Tomography ◽  
Contact Isolation ◽  
Neonatal Icu

SUMMARY We present the case of 33 weeks + weeks pregnant patient (G1P0), with proven COVID-19 infection by RT-PCR and, at admission, she presented with a dry cough and “tiredness when talking,”. Chest computed tomography was performed, which showed the presence of attenuations with ground glass opacification and bilateral consolidations. She then had a cesarean section because of maternal respiratory decompensation. She was transferred to the ICU of the same hospital with an O2 catheter. The newborn was transferred to the neonatal ICU of the same hospital in ambient air and maintained in respiratory and contact isolation. RT-PCR was collected for SARS-COV-2 at 6 h of life, which was positive. Faced with the knowledge gap on vertical transmission, RT-PCR for SARS-COV-2 at 6 h of life gives cause for concern, thus representing the possibility of vertical transmission by SARS-COV-2, although additional investigations are required.

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