Depression and Posttraumatic Stress Disorder Comorbidity

2014 ◽  
Author(s):  
Lisa M. Najavits ◽  
Nicole M. Capezza
Keyword(s):  
Risk Factors ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Traumatic Event ◽  
Future Research ◽  
Research Areas ◽  
Temporal Priority ◽  
Future Research Directions ◽  
Shared Risk

Depression and posttraumatic stress disorder (PTSD) are highly comorbid diagnoses following a traumatic event. In this chapter, we explore a range of topics related to comorbid depression and PTSD, including impact, prevalence, shared risk factors, temporal priority, key research areas, intervention strategies, and future research directions. Given the overlap in symptoms and shared risk factors, some researchers have suggested that the comorbidity between depression and PTSD following a traumatic event may be better understood as a single general mood disorder rather than two separate disorders. We examine evidence supporting both possibilities. We briefly review the two research areas that have received the most attention, namely comorbidity related to military traumas and interpersonal abuse. Practical implications, assessments, interventions, and treatment recommendations are also discussed.

scholarly journals The role of memory in posttraumatic stress disorder: implications for clinical practice

2016 ◽  
Vol 38 (3) ◽  
pp. 119-127 ◽  
Author(s):  
Marcelo Montagner Rigoli ◽  
Gustavo Ramos Silva ◽  
Fernando Rainho de Oliveira ◽  
Giovanni Kuckartz Pergher ◽  
Christian Haag Kristensen
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Clinical Practice ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Traumatic Event ◽  
Experimental Studies ◽  
Theoretical Models ◽  
Social Consequences ◽  
Future Research

Abstract Introduction: Posttraumatic stress disorder (PTSD) is a highly prevalent disorder with important social consequences. Several models have been developed with the aim of understanding the mechanisms underlying its symptoms. Intrusions are idiosyncratic symptoms that commonly take the form of involuntary recollection of images or flashbacks about the traumatic event. Objective: To review how memory is conceptualized in each of these models and the implications for clinical practice. Methods: A narrative review of the literature was conducted through analysis of the perspectives of memory in theoretical models of PTSD. Results: Two main perspectives were identified: 1) models in which specific mechanisms of memory for processing traumatic events are proposed, especially those based on clinical studies, and 2) models in which common mnemonic mechanisms are utilized to explain the phenomenon, primarily based on basic experimental research studies investigating memory. The different theories based on these approaches have led to distinct psychotherapy interventions. Conclusion: In order to clarify these discrepancies, future research should aim for the methodological rigor of experimental studies, while maintaining the ecological applicability of findings. Cognitive experimental psychopathology is therefore an area on which research funding should be focused. Such studies could elucidate the role of mnemonic aspects in PTSD and how they impact psychological treatments.

scholarly journals Prefrontal cortex, amygdala, and threat processing: implications for PTSD

2021 ◽  
Author(s):  
M. Alexandra Kredlow ◽  
Robert J. Fenster ◽  
Emma S. Laurent ◽  
Kerry J. Ressler ◽  
Elizabeth A. Phelps
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Prefrontal Cortex ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Large Body ◽  
Future Research ◽  
Healthy Humans ◽  
Foundational Research ◽  
Future Research Directions

AbstractPosttraumatic stress disorder can be viewed as a disorder of fear dysregulation. An abundance of research suggests that the prefrontal cortex is central to fear processing—that is, how fears are acquired and strategies to regulate or diminish fear responses. The current review covers foundational research on threat or fear acquisition and extinction in nonhuman animals, healthy humans, and patients with posttraumatic stress disorder, through the lens of the involvement of the prefrontal cortex in these processes. Research harnessing advances in technology to further probe the role of the prefrontal cortex in these processes, such as the use of optogenetics in rodents and brain stimulation in humans, will be highlighted, as well other fear regulation approaches that are relevant to the treatment of posttraumatic stress disorder and involve the prefrontal cortex, namely cognitive regulation and avoidance/active coping. Despite the large body of translational research, many questions remain unanswered and posttraumatic stress disorder remains difficult to treat. We conclude by outlining future research directions related to the role of the prefrontal cortex in fear processing and implications for the treatment of posttraumatic stress disorder.

Injury Increases the Risk for PTSD: An Examination of Potential Neurobiological and Psychological Mediators

CNS Spectrums ◽  
2006 ◽  
Vol 11 (8) ◽  
pp. 616-624 ◽  
Author(s):  
Danny Koren ◽  
Deborah Hemel ◽  
Ehud Klein
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Traumatic Event ◽  
Future Research ◽  
Physical Injury ◽  
Psychological Mechanisms ◽  
Bodily Injury ◽  
Growing Body ◽  
Pertinent Question

ABSTRACTA growing number of common traumatic events involve both physical and emotional injuries. In contrast to previously held beliefs, the rapidly growing body of literature shows quite convincingly that physical injury, over and above exposure to the traumatic event itself, increases rather than decreases the risk for posttraumatic stress disorder (PTSD). A pertinent question becomes how bodily injury contributes to the risk of developing PTSD. In this article, we review contemporary findings regarding the neurobiological and psychological mechanisms by which bodily injury may augment or independently contribute to chronic posttraumatic stress. In addition, we propose three theoretical pathways through which physical injury can increase the risk for PTSD. These pathways are: additive, unique, and recovery impeding. Finally, we highlight unresolved issues pertaining to each one of these pathways and propose directions for future research to address them.

scholarly journals Prevalence and risk factors for acute posttraumatic stress disorder during the COVID-19 outbreak

2021 ◽  
Vol 283 ◽  
pp. 123-129
Author(s):  
Luna Sun ◽  
Zhuoer Sun ◽  
Lili Wu ◽  
Zhenwen Zhu ◽  
Fan Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder

Factors Associated With Posttraumatic Stress Disorder Symptomology Among Women Who Have Experienced Sexual Assault in Canada

2019 ◽  
pp. 088626051986008
Author(s):  
Janice Du Mont ◽  
Holly Johnson ◽  
Cassandra Hill
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Sexual Assault ◽  
Posttraumatic Stress ◽  
Dating Violence ◽  
Sexual Victimization ◽  
Stress Disorder ◽  
General Social Survey ◽  
Future Research ◽  
Ptsd Symptoms ◽  
Sexually Assaulted

There is a dearth of information about the association of victim-related and assailant-related characteristics and posttraumatic stress disorder (PTSD) among sexually assaulted women. Recently, Statistics Canada included items measuring the possible presence of PTSD symptoms in their 2014 nationally representative General Social Survey on Victimization (GSS-V), for the purpose of improving the understanding of mental health impacts associated with sexual victimization. The present study used the GSS-V to examine the association of sociodemographic, health, and assailant characteristics and prior traumatic experiences in the form of physical or sexual dating violence, physical assault, stalking, childhood abuse, and witnessing of violence between parents with PTSD symptomology among sexually assaulted women. Among 319 women who reported experiencing at least one incident of sexual assault in the 12 months prior to the survey, 68.6% had experienced at least one negative emotional impact as a result, among whom, 43.6% reported past-month PTSD symptoms. Logistic regression modeling revealed that prior traumatic events in the form of physical or sexual dating violence, stalking, and having witnessed violence between parents were associated with higher odds of experiencing PTSD symptoms, as was having been sexually assaulted by a known assailant. In contrast, the odds of experiencing PTSD symptoms was lower for Aboriginal or visible minority women. The results suggest that PTSD symptoms in the near aftermath of sexual victimization are common, and there are a range of factors that contribute to the likelihood of developing these symptoms. Implications for future research are discussed.

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