scholarly journals Posttraumatic Stress Disorder in the Wake of Heart Disease: Prevalence, Risk Factors, and Future Research Directions

2005 ◽  
Vol 67 (5) ◽  
pp. 715-723 ◽  
Author(s):  
Helle Spindler ◽  
Susanne S. Pedersen
Keyword(s):  
Risk Factors ◽  
Posttraumatic Stress Disorder ◽  
Heart Disease ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Disease Prevalence ◽  
Future Research ◽  
Research Directions ◽  
Future Research Directions

Depression and Posttraumatic Stress Disorder Comorbidity

2014 ◽  
Author(s):  
Lisa M. Najavits ◽  
Nicole M. Capezza
Keyword(s):  
Risk Factors ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Traumatic Event ◽  
Future Research ◽  
Research Areas ◽  
Temporal Priority ◽  
Future Research Directions ◽  
Shared Risk

Depression and posttraumatic stress disorder (PTSD) are highly comorbid diagnoses following a traumatic event. In this chapter, we explore a range of topics related to comorbid depression and PTSD, including impact, prevalence, shared risk factors, temporal priority, key research areas, intervention strategies, and future research directions. Given the overlap in symptoms and shared risk factors, some researchers have suggested that the comorbidity between depression and PTSD following a traumatic event may be better understood as a single general mood disorder rather than two separate disorders. We examine evidence supporting both possibilities. We briefly review the two research areas that have received the most attention, namely comorbidity related to military traumas and interpersonal abuse. Practical implications, assessments, interventions, and treatment recommendations are also discussed.

scholarly journals Prefrontal cortex, amygdala, and threat processing: implications for PTSD

2021 ◽  
Author(s):  
M. Alexandra Kredlow ◽  
Robert J. Fenster ◽  
Emma S. Laurent ◽  
Kerry J. Ressler ◽  
Elizabeth A. Phelps
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Prefrontal Cortex ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Large Body ◽  
Future Research ◽  
Healthy Humans ◽  
Foundational Research ◽  
Future Research Directions

AbstractPosttraumatic stress disorder can be viewed as a disorder of fear dysregulation. An abundance of research suggests that the prefrontal cortex is central to fear processing—that is, how fears are acquired and strategies to regulate or diminish fear responses. The current review covers foundational research on threat or fear acquisition and extinction in nonhuman animals, healthy humans, and patients with posttraumatic stress disorder, through the lens of the involvement of the prefrontal cortex in these processes. Research harnessing advances in technology to further probe the role of the prefrontal cortex in these processes, such as the use of optogenetics in rodents and brain stimulation in humans, will be highlighted, as well other fear regulation approaches that are relevant to the treatment of posttraumatic stress disorder and involve the prefrontal cortex, namely cognitive regulation and avoidance/active coping. Despite the large body of translational research, many questions remain unanswered and posttraumatic stress disorder remains difficult to treat. We conclude by outlining future research directions related to the role of the prefrontal cortex in fear processing and implications for the treatment of posttraumatic stress disorder.

scholarly journals Prevalence and risk factors for acute posttraumatic stress disorder during the COVID-19 outbreak

2021 ◽  
Vol 283 ◽  
pp. 123-129
Author(s):  
Luna Sun ◽  
Zhuoer Sun ◽  
Lili Wu ◽  
Zhenwen Zhu ◽  
Fan Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder

Factors Associated With Posttraumatic Stress Disorder Symptomology Among Women Who Have Experienced Sexual Assault in Canada

2019 ◽  
pp. 088626051986008
Author(s):  
Janice Du Mont ◽  
Holly Johnson ◽  
Cassandra Hill
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Sexual Assault ◽  
Posttraumatic Stress ◽  
Dating Violence ◽  
Sexual Victimization ◽  
Stress Disorder ◽  
General Social Survey ◽  
Future Research ◽  
Ptsd Symptoms ◽  
Sexually Assaulted

There is a dearth of information about the association of victim-related and assailant-related characteristics and posttraumatic stress disorder (PTSD) among sexually assaulted women. Recently, Statistics Canada included items measuring the possible presence of PTSD symptoms in their 2014 nationally representative General Social Survey on Victimization (GSS-V), for the purpose of improving the understanding of mental health impacts associated with sexual victimization. The present study used the GSS-V to examine the association of sociodemographic, health, and assailant characteristics and prior traumatic experiences in the form of physical or sexual dating violence, physical assault, stalking, childhood abuse, and witnessing of violence between parents with PTSD symptomology among sexually assaulted women. Among 319 women who reported experiencing at least one incident of sexual assault in the 12 months prior to the survey, 68.6% had experienced at least one negative emotional impact as a result, among whom, 43.6% reported past-month PTSD symptoms. Logistic regression modeling revealed that prior traumatic events in the form of physical or sexual dating violence, stalking, and having witnessed violence between parents were associated with higher odds of experiencing PTSD symptoms, as was having been sexually assaulted by a known assailant. In contrast, the odds of experiencing PTSD symptoms was lower for Aboriginal or visible minority women. The results suggest that PTSD symptoms in the near aftermath of sexual victimization are common, and there are a range of factors that contribute to the likelihood of developing these symptoms. Implications for future research are discussed.

Abstract P127: Posttraumatic Stress Disorder and Risk for Coronary Heart Disease: A Meta-analytic Review

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Donald Edmondson ◽  
Ian M Kronish ◽  
Jonathan A Shaffer ◽  
Louise Falzon ◽  
Matthew M Burg
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Forest Plot ◽  
Increased Risk ◽  
Analytic Review

Context: Recent evidence suggests that posttraumatic stress disorder (PTSD) may be associated with increased risk for coronary heart disease (CHD). Objective: To determine the association of PTSD to incident CHD using systematic review and meta-analysis. Data Sources: Articles were identified by searching Ovid MEDLINE, PsycINFO, Scopus, Cochrane Library, PILOTS database, and through manual search of reference lists. Study Selection: Prospective cohort studies that assessed PTSD in participants free of CHD and assessed subsequent CHD or cardiac-specific mortality. Data Extraction: We extracted estimates of the association of PTSD to incident CHD, as well as study characteristics. Odds ratios were converted to hazard ratios (HR), and a random-effects model was used to pool results. Data Synthesis: Five studies met our inclusion criteria (N= 401,712); 4 of these included depression as a covariate. The pooled HR for the magnitude of the relationship between PTSD and CHD was 1.53 (95% CI, 1.27-1.84) before adjustment for depression. The pooled HR estimate for the 4 depression-adjusted estimates (N= 362,388) was 1.22 (95% CI, 1.05-1.42). Conclusion: PTSD is independently associated with increased risk for incident CHD, even after adjusting for depression and other covariates. Figure 1. Forest plot of association of PTSD to incident MI or cardiac mortality Note: The area of each square is proportional to the study’s weight in the meta-analysis, and each line represents the confidence interval around the estimate. The diamond represents the aggregate estimate, and its lateral points indicate confidence intervals for this estimate.

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