scholarly journals Community acquired acute kidney injury: findings from a large population cohort

QJM ◽  
2017 ◽  
Vol 110 (11) ◽  
pp. 741-746 ◽  
Author(s):  
J Holmes ◽  
J Geen ◽  
B Phillips ◽  
J D Williams ◽  
A O Phillips ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Large Population ◽  
Kidney Injury ◽  
Population Cohort ◽  
Large Population Cohort

scholarly journals Acute kidney injury electronic alerts in primary care ‐ findings from a large population cohort

QJM ◽  
2017 ◽  
Vol 110 (9) ◽  
pp. 577-582 ◽  
Author(s):  
J. Holmes ◽  
N. Allen ◽  
G. Roberts ◽  
J. Geen ◽  
J.D. Williams ◽  
...  
Keyword(s):  
Primary Care ◽  
Acute Kidney Injury ◽  
Large Population ◽  
Kidney Injury ◽  
Population Cohort ◽  
Electronic Alerts ◽  
Large Population Cohort

scholarly journals KDIGO-based acute kidney injury criteria operate differently in hospitals and the community—findings from a large population cohort

2016 ◽  
Vol 31 (6) ◽  
pp. 922-929 ◽  
Author(s):  
Simon Sawhney ◽  
Nick Fluck ◽  
Simon D. Fraser ◽  
Angharad Marks ◽  
Gordon J. Prescott ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Large Population ◽  
Kidney Injury ◽  
Injury Criteria ◽  
Population Cohort ◽  
Large Population Cohort

scholarly journals High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies

PLoS Biology ◽  
2020 ◽  
Vol 18 (9) ◽  
pp. e3000870 ◽  
Author(s):  
Habtamu B. Beyene ◽  
Gavriel Olshansky ◽  
Adam Alexander T. Smith ◽  
Corey Giles ◽  
Kevin Huynh ◽  
...  
Keyword(s):  
Cohort Studies ◽  
Large Population ◽  
High Coverage ◽  
Population Cohort ◽  
Large Population Cohort

scholarly journals Recurrent acute kidney injury: predictors and impact in a large population-based cohort

2019 ◽  
Vol 35 (8) ◽  
pp. 1361-1369 ◽  
Author(s):  
Jennifer Holmes ◽  
John Geen ◽  
John D Williams ◽  
Aled O Phillips
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Patient Outcomes ◽  
Large Population ◽  
Kidney Injury ◽  
Population Based ◽  
First Episode ◽  
Single Episode ◽  
Subsequent Episode ◽  
The Impact

Abstract Background This study examined the impact of recurrent episodes of acute kidney injury (AKI) on patient outcomes. Methods The Welsh National electronic AKI reporting system was used to identify all cases of AKI in patients ≥18 years of age between April 2015 and September 2018. Patients were grouped according to the number of AKI episodes they experienced with each patient’s first episode described as their index episode. We compared the demography and patient outcomes of those patients with a single AKI episode with those patients with multiple AKI episodes. Analysis included 153 776 AKI episodes in 111 528 patients. Results Of those who experienced AKI and survived their index episode, 29.3% experienced a second episode, 9.9% a third episode and 4.0% experienced fourth or more episodes. Thirty-day mortality for those patients with multiple episodes of AKI was significantly higher than for those patients with a single episode (31.3% versus 24.9%, P < 0.001). Following a single episode, recovery to baseline renal function at 30 days was achieved in 83.6% of patients and was significantly higher than for patients who had repeated episodes (77.8%, P < 0.001). For surviving patients, non-recovery of renal function following any AKI episode was significantly associated with a higher probability of a further AKI episode (33.4% versus 41.0%, P < 0.001). Furthermore, with each episode of AKI the likelihood of a subsequent episode also increased (31.0% versus 43.2% versus 51.2% versus 51.7% following a first, second, third and fourth episode, P < 0.001 for all comparisons). Conclusions The results of this study provide an important contribution to the debate regarding the need for risk stratification for recurrent AKI. The data suggest that such a tool would be useful given the poor patient and renal outcomes associated with recurrent AKI episodes as highlighted by this study.

Comparing the Comorbidity burden in Chronic Obstructive Pulmonary Disease and Heart Failure : evidence from a large population cohort

2019 ◽  
Author(s):  
Jonás Carmona-Pírez ◽  
Antonio Gimeno-Miguel ◽  
Beatriz Poblador-Plou ◽  
Jesús Díez Manglano ◽  
José María Marin Trigo ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Large Population ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Population Cohort ◽  
Comorbidity Burden ◽  
Large Population Cohort

scholarly journals The spectrum of thyroid disease and risk of new onset atrial fibrillation: a large population cohort study

BMJ ◽  
2012 ◽  
Vol 345 (nov27 1) ◽  
pp. e7895-e7895 ◽  
Author(s):  
C. Selmer ◽  
J. B. Olesen ◽  
M. L. Hansen ◽  
J. Lindhardsen ◽  
A.-M. S. Olsen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cohort Study ◽  
Thyroid Disease ◽  
Large Population ◽  
Population Cohort ◽  
Population Cohort Study ◽  
Onset Atrial Fibrillation ◽  
Large Population Cohort ◽  
New Onset
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