Physics must join with biology in better assessing risk from low-dose irradiation

2005 ◽  
Vol 117 (4) ◽  
pp. 346-356 ◽  
Author(s):  
L. E. Feinendegen ◽  
R. D. Neumann
Keyword(s):  
Low Dose ◽  
Circulation ◽  
1996 ◽  
Vol 93 (3) ◽  
pp. 529-536 ◽  
Author(s):  
John R. Laird ◽  
Andrew J. Carter ◽  
William M. Kufs ◽  
Timothy G. Hoopes ◽  
Andrew Farb ◽  
...  

2021 ◽  
Vol 165 ◽  
pp. 56-57
Author(s):  
Shota Naoe ◽  
Takahiro Kataoka ◽  
Hina Shuto ◽  
Junki Yano ◽  
Tetsuya Nakada ◽  
...  

Food Control ◽  
2021 ◽  
Vol 125 ◽  
pp. 107977
Author(s):  
Ziyi Hu ◽  
Yingping Xiao ◽  
Bingkui Wang ◽  
Tony Z. Jin ◽  
Wentao Lyu ◽  
...  

1995 ◽  
Vol 142 (2) ◽  
pp. 181 ◽  
Author(s):  
C. Mothersill ◽  
J. Harney ◽  
F. Lyng ◽  
D. Cottell ◽  
K. Parsons ◽  
...  

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Eon-Seok Lee ◽  
Yeo Jin Won ◽  
Byoung-Chul Kim ◽  
Daeui Park ◽  
Jin-Han Bae ◽  
...  
Keyword(s):  
Low Dose ◽  

Blood ◽  
2001 ◽  
Vol 97 (2) ◽  
pp. 557-564 ◽  
Author(s):  
Peter J. Quesenberry ◽  
Suju Zhong ◽  
Han Wang ◽  
Marc Stewart

Abstract We have previously shown that the keys to high-level nontoxic chimerism in syngeneic models are stem cell toxic, nonmyelotoxic host treatment as provided by 100-cGy whole-body irradiation and relatively high levels of marrow stem cells. This approach was unsuccessful in H-2 mismatched B6.SJL to BALB/c marrow transplants, but with tolerization, stable multilineage chimerism was obtained. Ten million B6.SJL spleen cells were infused intravenously into BALB/c hosts on day −10 and (MR-1) anti-CD40 ligand monoclonal antibody (mAb) injected intraperitoneally at varying levels on days −10, −7, −3, 0, and +3 and the BALB/c mice irradiated (100 cGy) and infused with 40 million B6.SJL/H-2 mismatched marrow cells on day 0. Stable multilineage chimerism at levels between 30% to 40% was achieved in the great majority of mice at 1.6 mg anti-CD40 ligand mAb per injection out to 64 weeks after transplantation, without graft-versus-host disease. The transplanted mice were also tolerant of donor B6.SJL, but not third-party CBA/J skin grafts at 8 to 9 and 39 to 43 weeks after marrow transplantation. These data provide a unique model for obtaining stable partial chimerism in H-2 mismatched mice, which can be applied to various clinical diseases of man such as sickle cell anemia, thalassemia, and autoimmune disorders.


2011 ◽  
Vol 80 (3) ◽  
pp. 885-892 ◽  
Author(s):  
Sean S. Park ◽  
John L. Chunta ◽  
John M. Robertson ◽  
Alvaro A. Martinez ◽  
Ching-Yee Oliver Wong ◽  
...  

2013 ◽  
Vol 15 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Kaoru Takabayashi ◽  
Kazuhiro Kashiwagi ◽  
Tetsuya Kawata ◽  
Toshiro Sato ◽  
Katsuyoshi Matsuoka ◽  
...  

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