Effect of tailoring on weight loss among young adults receiving digital interventions: an 18 month randomized controlled trial

2021 ◽  
Author(s):  
Melissa A Napolitano ◽  
Jessica A Whiteley ◽  
Meghan Mavredes ◽  
Ashley Hogan Tjaden ◽  
Samuel Simmens ◽  
...  
Keyword(s):  
Weight Loss ◽  
Young Adults ◽  
Treatment Group ◽  
Text Messaging ◽  
Controlled Trial ◽  
Stepped Care ◽  
Baseline Body Mass Index ◽  
Treatment Interaction ◽  
Weight Loss Outcomes ◽  
Weight Loss Treatments

Abstract Weight loss outcomes among young adults in technology-based programs have been equivocal. The purpose of this study was to deliver digital weight loss treatments to young adults and examine the 6, 12, and 18 month effects on weight loss. Young adults with overweight/obesity (N = 459; 23.3 ± 4.4 years) were recruited from two university sites and randomly assigned to receive through Facebook and text messaging either personalized (TAILORED; n = 150) or generic (TARGETED; n = 152) weight loss information, messages, and feedback or general healthy body content (e.g., body image, sleep; CONTROL; n = 157). The study was powered to detect a 2.1-kg difference at all time points with the primary outcome being 18 months. There was no overall effect of treatment group on 6, 12, or 18 month weight loss (ps = NS). However, at 6 months, those in TAILORED who were highly engaged (completing >66%) lost more weight compared to CONTROL (−2.32 kg [95% confidence intervals: −3.90, −0.74]; p = .004), with the trend continuing at 12 months. A significant baseline body mass index (BMI) by treatment group interaction (p = .004) was observed at 6 months. Among participants in the lowest baseline BMI category (25–27.5 kg/m2), those in TAILORED lost 2.27 kg (−3.86, −0.68) more, and those in TARGETED lost 1.72 kg (−3.16, −0.29) more than CONTROL after adjusting for covariates. Among participants with a BMI between 27.5 and 30 kg/m2, those in TAILORED lost 2.20 kg (−3.90, −0.51) more than participants in TARGETED. Results did not persist over time with no treatment interaction at 12 or 18 months. Initial body weight should be considered when recommending weight loss treatments for young adults. More intensive interventions or stepped care approaches may be needed for young adults with obesity.

Abstract P183: FTO Genotype, Dietary Protein, and Change in Appetite: the Pounds Lost trial

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Tao Huang ◽  
Qibin Qi ◽  
Yanping Li ◽  
Frank Hu ◽  
George A Bray ◽  
...  
Keyword(s):  
Weight Loss ◽  
Protein Interactions ◽  
Dietary Protein ◽  
Controlled Trial ◽  
High Protein Diet ◽  
Diet Group ◽  
Protein Diet ◽  
Baseline Body Mass Index ◽  
Food Cravings ◽  
Fto Rs9939609

Objective: A common "obesity-risk" variant rs9939609 in the FTO gene was recently found to affect appetite, and the gene is sensitive to regulation of amino acids. We examined the interaction between FTO genotype and protein intake on the long-term changes in appetite in a randomized controlled trial. Research Design and Methods: We genotyped FTO rs9939609 in 737 overweight adults in the 2-year Preventing Overweight Using Novel Dietary Strategies (Pounds Lost) trial and assessed four appetite related traits including cravings, fullness, hunger, and prospective consumption. Results: We found that dietary protein significantly modified genetic effects on changes in food cravings at 6 months, after adjustment for age, sex, ethnicity, baseline body mass index, weight change, baseline value for food cravings (P for interaction=0.027). The A allele was associated with a greater decrease in food cravings among the participants with high protein diet intake (P=0.027), but not in those low protein diet group (P= 0.384). Weight regain from 6 months to 24 months attenuated the gene-protein interactions. Protein intakes did not modify the FTO genotype effects on other appetite measures. Conclusions: Our data suggest that individuals with the FTO rs9939609 A allele might obtain more benefits in reduction of food cravings by choosing a hypocaloric and higher protein weight-loss diet. Keywords: diet, genetic variation, food cravings, gene-diet interaction, weight-loss trial

Abstract MP27: Cellphone Intervention for You (CITY): A Randomized, Controlled Trial of Behavioral Weight Loss Intervention by Cellphone or Personal Coaching for Young Adults

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Laura P Svetkey ◽  
Stephen S Intille ◽  
Bryan C Batch ◽  
Leonor Corsino ◽  
Crystal C Tyson ◽  
...  
Keyword(s):  
Weight Loss ◽  
Young Adults ◽  
Controlled Trial ◽  
Personal Contact ◽  
Control Group ◽  
Weight Loss Intervention ◽  
Behavioral Weight Loss ◽  
National Guidelines ◽  
Personal Coaching ◽  
Behavioral Weight Loss Intervention

Background: Obesity affects young adults, leading to future morbidity and mortality. Early behavioral intervention may promote long-term weight control. Mobile technology-based (mHealth) interventions may be particularly effective in young adults. We compared both an mHealth behavioral weight loss intervention and a personal coaching weight loss intervention to no intervention (and to each other) in overweight/obese young adults. Methods: We randomized 365 generally healthy adults age 18-35 years with BMI > 25 kg/m2 (overweight or obese) to 24-months of intervention delivered primarily via investigator-designed cell phone (CP) or intervention delivered primarily via in-person (6 weekly) and by phone (23 monthly) coaching (PC), compared to usual care control group (Control). Primary outcome was weight change from baseline to 24 months. This study was conducted as part of the Early Adult Reduction of weight through LifestYle (EARLY) cooperative trials. Results: Randomized participants (N=365) had mean BMI 35 kg/m2, mean age 29yrs, were 70% women, 36% African American, 6% Latino. Final weight was obtained in 86%; missing weight was multiply imputed. At 24 months, weight loss was not different in either PC or CP vs Control (see Figure). Weight loss in PC was significantly greater than Control at 6 months. From baseline to 24 months, clinically significant weight loss (> 3% per national guidelines) occurred in 40% of PC, 34% of CP, and 30% of Control. Conclusions: mHealth alone may not be sufficient for weight loss in young adults but mHealth-enhanced contact with an interventionist has a modest short-term effect. Future interventions should maximize the complementarity of mHealth and personal contact to achieve larger and more sustained effect.

scholarly journals The Association Between Engagement and Weight Loss Through Personal Coaching and Cell Phone Interventions in Young Adults: Randomized Controlled Trial

10.2196/10471 ◽  
2018 ◽  
Vol 6 (10) ◽  
pp. e10471 ◽  
Author(s):  
Pao-Hwa Lin ◽  
Steven Grambow ◽  
Stephen Intille ◽  
John A Gallis ◽  
Tony Lazenka ◽  
...  
Keyword(s):  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Young Adults ◽  
Cell Phone ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Personal Coaching

scholarly journals Text messaging and brief phone calls for weight loss in overweight and obese English- and Spanish-speaking adults: A 1-year, parallel-group, randomized controlled trial

PLoS Medicine ◽  
2019 ◽  
Vol 16 (9) ◽  
pp. e1002917 ◽  
Author(s):  
Job G. Godino ◽  
Natalie M. Golaszewski ◽  
Greg J. Norman ◽  
Cheryl L. Rock ◽  
William G. Griswold ◽  
...  
Keyword(s):  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Text Messaging ◽  
Controlled Trial ◽  
Spanish Speaking ◽  
Randomized Controlled ◽  
Phone Calls ◽  
Parallel Group

scholarly journals Improving Calcium Knowledge and Intake in Young Adults Via Social Media and Text Messages: Randomized Controlled Trial (Preprint)

2019 ◽  
Author(s):  
Anika Rouf ◽  
Monica Nour ◽  
Margaret Allman-Farinelli
Keyword(s):  
Social Media ◽  
Randomized Controlled Trial ◽  
Young Adults ◽  
Calcium Intake ◽  
Text Messaging ◽  
Habit Formation ◽  
Controlled Trial ◽  
Text Messages ◽  
Control Group ◽  
Randomized Controlled

BACKGROUND Calcium is an important nutrient for the attainment of peak bone mass during adolescence and young adulthood. However, these life phases are characterized as hard to reach for health promotion. Social media platforms offer a promising channel as they are relatively low cost but used ubiquitously by youth. OBJECTIVE The aim of the CAlcium Nutrition-Dietary Opportunities (CAN-DO) study was to conduct a randomized controlled trial to test the effectiveness of Facebook alone or with text messaging as channels to deliver a theory-based program to encourage optimal calcium intake. METHODS The intervention was a 3-arm parallel trial. Young adults aged 18 to 25 years were recruited through university and social media for a 6-week trial. Participants were randomized to 1 of the 3 arms (ie, Facebook posts, Facebook posts plus text messages, and control group that received an electronic leaflet containing information on calcium intake). The primary outcome was change in intake of milk and other calcium-rich foods, and secondary outcomes were knowledge, self-efficacy, motivation, and habit formation concerning calcium-rich foods. Changes were assessed before and after the intervention, and the differences in change between groups were compared using multivariate regression models with multiple imputations for missing data. RESULTS A total of 211 participants (64/211, 30.3% males) participated (mean age 21.4 years, SD 2.1) in this study. At the end of the program, no increase in milk intake (odds ratio [OR] 1.51, 95% CI 0.61-3.75 Facebook; OR 1.77, 95% CI 0.74-4.24 Facebook plus text messages; <i>P</i>=.41) nor calcium-rich food was detected (<i>P</i>=.57). There was a significant improvement in knowledge in the Facebook plus text messages group (<i>P</i>&lt;.001), but habit formation improved less than that in the other 2 groups (<i>P</i>=.01). Our results showed a moderate level of engagement with intervention content and positive qualitative feedback from participants. CONCLUSIONS The CAN-DO study delivered via Facebook (with the additional support of text messages) was found to improve knowledge and was acceptable among young adults. However, further research is needed to better understand social media engagement and how to optimize the program for participants to be sufficiently motivated to increase their intake of calcium-rich foods. CLINICALTRIAL Australian New Zealand Clinical Trials Registry ACTRN12620000097943; http://www.anzctr.org.au/ACTRN12620000097943.aspx

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