scholarly journals Low Rates of Hepatotoxicity in HIV-infected Children on Anti-retroviral Therapy with and without Isoniazid Prophylaxis

2012 ◽  
Vol 58 (1) ◽  
pp. 85-85
Author(s):  
D. Gray ◽  
J. Nuttall ◽  
C. Lombard ◽  
M.-a. Davies ◽  
L. Workman ◽  
...  
Keyword(s):  
Isoniazid Prophylaxis

Letters to the Editor

PEDIATRICS ◽  
1967 ◽  
Vol 40 (4) ◽  
pp. 691-693
Author(s):  
STARKEY D. DAVIS ◽  
RALPH J. WEDGWOOD
Keyword(s):  
Public Health ◽  
Placebo Group ◽  
Health Service ◽  
Excess Mortality ◽  
Public Health Service ◽  
Letters To The Editor ◽  
The Public ◽  
Mental Hospitals ◽  
The One ◽  
Isoniazid Prophylaxis

Dr. Yerushalmy points out the excess mortality in the isoniazid pupulation in two trials: contacts of new cases and patients in mental hospitals. He failed to mention that the Public Health Service has conducted five other isoniazid prophylaxis trials (Table I). In the six trials listed, excluding the one in institutions, the isoniazid groups had more deaths in three trials, the placebo group had more deaths in two trials, and in one trial the number of deaths in each group was equal.

scholarly journals Attentional function in secondary school students receiving isoniazid prophylaxis for tuberculosis infection

2000 ◽  
Vol 124 (1) ◽  
pp. 97-101 ◽  
Author(s):  
D. ANDERSON ◽  
V. ANDERSON ◽  
L. PENTLAND ◽  
S. SAWYER ◽  
M. STARR ◽  
...  
Keyword(s):  
Secondary School ◽  
Processing Speed ◽  
Secondary School Students ◽  
School Students ◽  
Attentional Function ◽  
Speed Of Information Processing ◽  
Serial Addition ◽  
Cognitive Side Effects ◽  
Poor Concentration ◽  
Isoniazid Prophylaxis

Reports have suggested that isoniazid treatment may be associated with poor concentration and subtle reduction in memory. This study examines attentional function and processing speed in a group of 25 adolescents who received isoniazid prophylaxis for at least 6 months. As adolescents often face major educational assessment milestones, such cognitive side effects may have important implications. Participants were assessed before treatment, 1 month into treatment and at least 1 week after treatment cessation. Measures included the Paced Auditory Serial Addition Test and subtests of the appropriate Wechsler scale sensitive to attention and speed of information processing. Isoniazid does not appear to cause significant adverse effects on attentional function in adolescents.

scholarly journals Adherence to isoniazid prophylaxis among HIV-infected children: a randomized controlled trial comparing two dosing schedules

BMC Medicine ◽  
2009 ◽  
Vol 7 (1) ◽  
Author(s):  
Stanzi M le Roux ◽  
Mark F Cotton ◽  
Jonathan E Golub ◽  
David M le Roux ◽  
Lesley Workman ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Isoniazid Prophylaxis

Isoniazid Prophylaxis-Reply

JAMA ◽  
1987 ◽  
Vol 258 (7) ◽  
pp. 911
Author(s):  
David N. Rose
Keyword(s):  
Isoniazid Prophylaxis
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