scholarly journals Maternal Low Protein Diet Reduces Birth Weight And Increases Brown Adipose Tissue UCP‐1 and FNDC5 Gene Expression in Male Neonatal Sprague‐Dawley Rats

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Kate Claycombe ◽  
Emilie Vomhof‐DeKrey ◽  
James Roemmich ◽  
Turk Rhen ◽  
Othman Ghribi
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Birth Weight ◽  
Brown Adipose Tissue ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Sprague Dawley ◽  
Low Protein ◽  
Sprague Dawley Rats ◽  
Brown Adipose

scholarly journals Low protein diet changes the energetic balance and sympathetic activity in brown adipose tissue of growing rats

Nutrition ◽  
2009 ◽  
Vol 25 (11-12) ◽  
pp. 1186-1192 ◽  
Author(s):  
Suélem Aparecida de França ◽  
Maísa Pavani dos Santos ◽  
Maria Antonieta Rissato Garófalo ◽  
Luiz Carlos Navegantes ◽  
Isis do Carmo Kettelhut ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Sympathetic Activity ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Growing Rats ◽  
Low Protein ◽  
Brown Adipose ◽  
Energetic Balance

A Maternal Low-protein Diet during Gestation Induces Hepatic Autophagy-related Gene Expression in a Sex-specific Manner in Sprague-Dawley Rats

2021 ◽  
pp. 1-29
Author(s):  
Mingzhu Cai ◽  
Jie Zhang ◽  
Hong Chen ◽  
Yuan-Xiang Pan
Keyword(s):  
Gene Expression ◽  
Transcription Factors ◽  
Control Diet ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Related Gene ◽  
Sprague Dawley ◽  
Protein Levels ◽  
Low Protein ◽  
Sprague Dawley Rats

Abstract This study investigates the mechanism by which maternal protein restriction induces hepatic autophagy-related gene expression in the offspring of rats. Pregnant Sprague-Dawley rats were fed either a control diet (C, 18% energy from protein) or a low-protein diet (LP, 8.5% energy from protein) during gestation, followed by the control diet during lactation and post-weaning. Liver tissue was collected from the offspring at postnatal day 38 and divided into four groups according to sex and maternal diet (F-C, F-LP, M-C, and M-LP) for further analysis. Autophagy-related mRNA and protein levels were determined by real-time PCR and Western blotting, respectively. In addition, chromatin immunoprecipitation (ChIP) was performed to investigate the interactions between transcription factors and autophagy-related genes. Protein levels of p-eIF2a and ATF4 were increased only in the female offspring born to dams fed the LP diet. Correlatively, the mRNA expression of hepatic autophagy-related genes including Map1lc3b, P62/Sqstm1, Becn1, Atg3, Atg7, and Atg10 was significantly greater in the F-LP group than in the F-C group. Furthermore, ChIP results showed greater ATF4 and C/EBP homology protein (CHOP) binding at the regions of a set of autophagy-related genes in the F-LP group than in the F-C group. Our data demonstrated that a maternal LP diet transcriptionally programmed hepatic autophagy-related gene expression only in female rat offspring. This transcriptional program involved the activation of the eIF2α/ATF4 pathway and intricate regulation by transcription factors ATF4 and CHOP.

Consumption of a Low Protein Diet Increases Norepinephrine Turnover in Brown Adipose Tissue of Adult Rats

1984 ◽  
Vol 114 (3) ◽  
pp. 543-549 ◽  
Author(s):  
Arlene V. Kevonian ◽  
Jerry G. Vander Tuig ◽  
Dale R. Romsos
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Adult Rats ◽  
Low Protein ◽  
Norepinephrine Turnover ◽  
Brown Adipose

DOMINANT EFFECT OF SUPPLEMENTED-SUCROSE ON THE LOW PROTEIN DIET-INDUCED INCREASE IN BLOOD PRESSURE OF SPRAGUE-DAWLEY RATS

2001 ◽  
Vol 23 (7) ◽  
pp. 569-578
Author(s):  
Michiyo Endoh ◽  
Asako Kunieda ◽  
Takashi Yoneyama ◽  
Kazuhisa Ohishi ◽  
Akira Hishida ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Sprague Dawley ◽  
Dominant Effect ◽  
Low Protein ◽  
Sprague Dawley Rats

scholarly journals Maternal low protein diet leads to placental angiogenic compensation via dysregulated M1/M2 macrophages and TNFα expression in Sprague-Dawley rats

2016 ◽  
Vol 118 ◽  
pp. 9-17 ◽  
Author(s):  
Emilie Vomhof-DeKrey ◽  
Diane Darland ◽  
Othman Ghribi ◽  
Amy Bundy ◽  
James Roemmich ◽  
...  
Keyword(s):  
Protein Diet ◽  
Low Protein Diet ◽  
M2 Macrophages ◽  
Sprague Dawley ◽  
Low Protein ◽  
Sprague Dawley Rats
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