A Biphasic Tumor of the Mediastinum with Features of Synovial Sarcoma

1989 ◽  
Vol 13 (6) ◽  
pp. 490-499 ◽  
Author(s):  
Gary B. Witkin ◽  
Markku Miettinen ◽  
Juan Rosai
Keyword(s):  
Synovial Sarcoma ◽  
Biphasic Tumor

scholarly journals Rare case of primary esophageal synovial sarcoma with (x;18) translocation presenting as dysphagia

2021 ◽  
Vol 9 (6) ◽  
pp. 1782
Author(s):  
Anuradha Sekaran ◽  
Purva Shinde ◽  
Veena Vanere ◽  
Mohan Ramchandani ◽  
Duvvur N. Reddy
Keyword(s):  
Differential Diagnosis ◽  
Synovial Sarcoma ◽  
Gastrointestinal Stromal Tumors ◽  
Rare Case ◽  
Rare Tumor ◽  
Rare Occurrence ◽  
Stromal Tumors ◽  
Synovial Sarcomas ◽  
Biphasic Tumor ◽  
Tumor Entities

Synovial sarcoma (SS) in young adult mainly involves periarticular region of the extremities. Synovial sarcomas are exceedingly rare neoplasms of the digestive tract. In this report, we describe a very rare occurrence of primary SS of the esophagus in a 30-year-old female. Patient presented with dysphagia. Endoscopy showed submucosal esophageal polyp. Piecemeal polypectomy was done. Histologically, the tumor demonstrated biphasic morphology with epithelial and mesnchymal component. Tumor cells expressed pancytokeratin, bcl-2 and CD99 antigens. Differential diagnosis of synovial sarcoma and epithelial mesenchymal biphasic tumor was made. Cytogenetics was done to confirm the diagnosis of SS. It showed translocation (x;18). Synovial sarcomas are very rare tumor entities, particularly in the gastrointestinal tract and are likely to be mistaken with other more common tumors such as gastrointestinal stromal tumors.

Spindle Cell Carcinoma of the Tongue: Fallacies in Its Diagnosis

2018 ◽  
Vol 3 (02) ◽  
Author(s):  
Amrit Kaur Kaler, Shweta C, Smitha Chandra B.C, Rajeev Naik
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Cell Population ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Biphasic Tumor ◽  
Carcinoma Of The Tongue ◽  
Ihc Markers

Spindle cell carcinoma is a rare aggressive biphasic tumor, composed of neoplastic proliferation of both epithelial (squamous) and spindle cell population. It constitutes about 1% of all oral cavity tumors 2a and is almost rare on the tongue; only few cases have been reported so far. This variant of squamous cell carcinoma, comprises major diagnostic problems due to its varied histomorphology and resemblance to sarcomatous lesion; hence diligent screening and IHC markers are mandatory for its diagnosis.

Systematic literature review of clinical outcomes in adults with metastatic or advanced synovial sarcoma

2020 ◽  
Vol 16 (35) ◽  
pp. 2997-3013
Author(s):  
Kentaro Kogushi ◽  
Michael LoPresti ◽  
Shunya Ikeda
Keyword(s):  
Synovial Sarcoma ◽  
High Frequency ◽  
Clinical Evidence ◽  
Systemic Treatment ◽  
Progression Free Survival ◽  
Treatment Modalities ◽  
Free Survival ◽  
New Treatment ◽  
Poor Outcomes

Background: Synovial sarcoma (SS) is a rare, aggressive soft tissue sarcoma with a poor prognosis after metastasis. The objective of this study was to conduct a systematic review of the clinical evidence for therapeutic options for adults with metastatic or advanced SS. Materials & methods: Relevant databases were searched with predefined keywords. Results: Thirty-nine publications reported clinical data for systemic treatment and other interventions. Data on survival outcomes varied but were generally poor (progression-free survival: 1.0–7.7 months; overall survival: 6.7–29.2 months) for adults with metastatic and advanced SS. A high frequency of neutropenia with systemic treatment and low quality of life post-progression were reported. Conclusion: Reported evidence suggests poor outcomes in adults with metastatic and advanced SS and the need for the development of new treatment modalities.

scholarly journals Recurrent pulmonary synovial sarcoma effectively treated with amrubicin: A case report

2015 ◽  
Vol 9 (5) ◽  
pp. 1947-1949 ◽  
Author(s):  
HIROAKI SATOH ◽  
NORIO TAKAYASHIKI ◽  
TOSHIHIRO SHIOZAWA ◽  
KUNIHIKO MIYAZAKI ◽  
GEN OHARA ◽  
...  
Keyword(s):  
Case Report ◽  
Synovial Sarcoma

Synovial sarcoma

1981 ◽  
Vol 9 (1) ◽  
pp. 41-45 ◽  
Author(s):  
R. Beverly Raney
Keyword(s):  
Synovial Sarcoma
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