A prospective study of HIV-2 prevalence in France Anne-Marie Couroucé and the ‘Retrovirus’ study group of the French Society of Blood Transfusion

AbstractGold eyelid implantation is widely considered the procedure of choice to reanimate the upper eyelid in paralytic lagophthalmos. Commercially supplied implants are not readily available in all places and are sometimes cumbersome to import.Objective:We aimed to devise a method whereby every surgeon performing gold eyelid implantation could have easy and quick access to the implant. Furthermore, we aimed to develop a means of creating an implant of the exact weight required for complete eyelid closure.Study design and setting:A prospective study was performed from 1997 to 2005 in a tertiary research hospital, involving 50 subjects requiring gold upper eyelid implantation and using the technique in question.Results:Only patients with a minimum follow up of one year were included in the study group. Symptoms improved in 96 per cent of subjects, who were able to dispense with eyedrops and eye ointments. Visual acuity improved in 92 per cent of patients. There were two extrusions amongst the early cases.Conclusion and significance:Customised gold eyelid implantation offers an alternative in regions where commercial implants are not easily obtained.

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Transfusion-transmitted human T-cell lymphotropic virus type I infection in Taiwan: a true risk and occasional coinfection with hepatitis C virus shown in a prospective study

Blood ◽

10.1182/blood.v84.3.934.bloodjournal843934 ◽

1994 ◽

Vol 84 (3) ◽

pp. 934-940

Author(s):

JT Wang ◽

MT Lin ◽

PJ Chen ◽

JC Sheu ◽

JT Lin ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

T Cell ◽

Blood Transfusion ◽

Prospective Study ◽

Family Members ◽

Type I ◽

Serum Samples ◽

Human T Cell ◽

A Prospective Study

To study the incidence of human T-cell lymphotropic virus (HTLV) after blood transfusion in Taiwan, serum samples from 699 patients in a prospective study were examined for seroreactivity of anti-HTLV. By an enzyme immunoassay, 9 of the 699 recipients were repeatedly positive. Serial serum samples of these 9 patients were then confirmed with a Western blot analysis and with a polymerase chain reaction (PCR) assay for HTLV-I genome. Four were already positive for anti-HTLV before transfusion, 1 carried antibodies to HTLV-I transiently after transfusion, and only 4 cases had de nova seroconversions. These patients and their family members were called back and tested for HTLV- I genome in the peripheral blood mononuclear cell (PBMC) and plasma. All the serologically positive patients, except the “transient one,” were positive for HTLV sequences in the PBMCs. Viral sequences could also be detected in several serum or plasma samples. In the family members, only the spouse of a pretransfusion-positive patient was infected. These results suggested that approximately 0.6% of the blood recipients were infected by HTLV-I through transfusion in Taiwan, and that the frequency of intrafamilial HTLV-I transmission is low. We also observed the unusual coinfection by both HTLV-I and hepatitis C virus in 2 patients, and superinfection of hepatitis C virus after blood transfusion in 1 HTLV-I carrier. Cases of coinfection suggest a prevalence of both viruses in blood donors and warrant further screening.

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Splenectomy in children with idiopathic thrombocytopenic purpura: A prospective study of 134 children from the Intercontinental Childhood ITP Study Group

Pediatric Blood & Cancer ◽

10.1002/pbc.21108 ◽

2007 ◽

Vol 49 (6) ◽

pp. 829-834 ◽

Cited By ~ 65

Author(s):

Thomas Kühne ◽

Victor Blanchette ◽

George R. Buchanan ◽

Ugo Ramenghi ◽

Hugo Donato ◽

...

Keyword(s):

Prospective Study ◽

Idiopathic Thrombocytopenic Purpura ◽

Study Group ◽

Thrombocytopenic Purpura ◽

A Prospective Study

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Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status – a prospective study

The Journal of Laryngology & Otology ◽

10.1017/s0022215120001863 ◽

2020 ◽

Vol 134 (8) ◽

pp. 717-720 ◽

Cited By ~ 1

Author(s):

MH Hussain ◽

M Mair ◽

P Rea

Keyword(s):

Severe Acute Respiratory Syndrome ◽

Prospective Study ◽

Control Group ◽

Study Group ◽

Chain Reaction ◽

Polymerase Chain Reaction Testing ◽

The Mean ◽

Polymerase Chain ◽

The Difference ◽

A Prospective Study

AbstractObjectiveTo evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.MethodsA prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.ResultsThe mean age was 66.5 ± 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 ± 22.4 years (p = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p = 0.05).ConclusionEpistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. This may serve as a useful additional criterion for screening patients.

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