USE OF THE d-DIMER QUANTITATIVE ASSAY AND IMPEDANCE PLETHYSMOGRAPHY IN THE DIAGNOSIS OF VENOUS THROMBOEMBOLIC DISEASE AMONG PATIENTS WITH ACQUIRED BRAIN INJURY

Author(s):  
Stuart A. Yablon ◽  
Jonathan R. Strayer ◽  
Lourdes M. Cuellar
1996 ◽  
Vol 75 (01) ◽  
pp. 011-013 ◽  
Author(s):  
Philippe de Moerloose ◽  
Sylvie Desmarais ◽  
Henri Bounameaux ◽  
Guido Reber ◽  
Arnaud Perrier ◽  
...  

SummaryThe performance of a new automated ELISA for a rapid, individual and quantitative measurement of plasma D-dimer (VIDAS D-dimer) has been evaluated. First, a study of 100 patients was performed in order to choose the best couple of antibodies in comparison with an already clinically validated ELISA. Then the results were certified in a prospective study including 195 consecutive patients suspected of pulmonary embolism (PE). For a cut-off level of 500 ng/ml VIDAS D-dimer showed a sensitivity of 100% (95% confidence interval 92-100), a specificity of 37.6%, a negative predictive value of 100% (95% CI 93.3-100) and a positive predictive value of 33.1%. During a 6 months’ follow-up no patient (95% CI 0-6.4) with D-dimer <500 ng/ml presented a new suspicion of venous thromboembolic disease. These results suggest that this rapid and single-dose ELISA provides a very useful tool for the clinician to exclude on a day-to-day basis the diagnosis of PE.


1987 ◽  
Vol 21 (4) ◽  
pp. 307A-307A
Author(s):  
Chris Turner ◽  
Maureen Andrew ◽  
Russell Hull ◽  
Gerry Gill ◽  
Jack Hirsh

2019 ◽  
Vol 2 ◽  
pp. 100026 ◽  
Author(s):  
Pablo Zubiate ◽  
Aitor Urrutia ◽  
Carlos R. Zamarreño ◽  
Josune Egea-Urra ◽  
Joaquín Fernández-Irigoyen ◽  
...  

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