Interchanging Scores Between Clinical Dementia Rating Scale and Global Deterioration Scale

2003 ◽  
Vol 17 (2) ◽  
pp. 98-105 ◽  
Author(s):  
Seong Hye Choi ◽  
Byung Hwa Lee ◽  
Seonwoo Kim ◽  
Dong Seok Hahm ◽  
Jee Hyang Jeong ◽  
...  
2020 ◽  
pp. 089198872094423
Author(s):  
Thaís Bento Lima-Silva ◽  
Eneida Mioshi ◽  
Valéria Santoro Bahia ◽  
Mário Amore Cecchini ◽  
Luciana Cassimiro ◽  
...  

Introduction: There is a shortage of validated instruments to estimate disease progression in frontotemporal dementia (FTD). Objectives: To evaluate the ability of the FTD Rating Scale (FTD-FRS) to detect functional and behavioral changes in patients diagnosed with the behavioral variant of FTD (bvFTD), primary progressive aphasia (PPA), and Alzheimer disease (AD) after 12 months of the initial evaluation, compared to the Clinical Dementia Rating scale−frontotemporal lobar degeneration (CDR-FTLD) and the original Clinical Dementia Rating scale (CDR). Methods: The sample consisted of 70 individuals, aged 40+ years, with at least 2 years of schooling, 31 with the diagnosis of bvFTD, 12 with PPA (8 with semantic variant and 4 with non-fluent variant), and 27 with AD. The FTD-FRS, the CDR, and the 2 additional CDR-FTLD items were completed by a clinician, based on the information provided by the caregiver with frequent contact with the patient. The Addenbrooke Cognitive Examination-Revised was completed by patients. After 12 months, the same protocol was applied. Results: The FTD-FRS, CDR-FTLD, and CDR detected significant decline after 12 months in the 3 clinical groups (exception: FTD-FRS for PPA). The CDR was less sensitive to severe disease stages. Conclusions: The FTD-FRS and the CDR-FTLD are especially useful tools for dementia staging in AD and in the FTD spectrum.


2009 ◽  
Vol 5 (4S_Part_10) ◽  
pp. P292-P292 ◽  
Author(s):  
Hee Jin Kang ◽  
Young-Hee Chang ◽  
Ha-Ry Na ◽  
Min Jae Baek ◽  
Hyun Jung Kim ◽  
...  

2016 ◽  
Vol 7 (2) ◽  
pp. 57-62
Author(s):  
Maria L Chuhlovina ◽  
Denis V Zaslavsky ◽  
Ekaterina A Bichun

The research objective is investigation of clinical manifestations of neurosyphilis in women of reproductive age. The diagnoses were based on complaints, anamnestic information, neurological examinations, dermatovenerology consultations, serological blood and liquor tests. All the patients underwent psychometric tests. The following methods were used: mini-mental state examination (MMSE), “Frontal Assessment Battery”, Clinical Dementia Rating scale, Clock drawing test, “Information-Memory-Consideration Concentration” test, Mattis Dementia Rating Scale. Nine patients with early neurosyphilis (between the ages of 18 to 40) and eight patients with late neurosyphilis (between the ages of 28 to 43) were surveyed. Syphilitic meningitis (six cases), meningovascular neurosyphilis (three cases) were found in patients with early neurosyphilis. As for the patients with late neurosyphilis, two of them were diagnosed to have syphilitic meningitis, two patients had meningovascular neurosyphilis, two had progressive paralysis, tabes dorsalis was identified in one patient, one had taboparalysis. Only three patients showed specific skin and mucic manifestations. The patients at all the stages of neurosyphilis demonstrated mild cognitive impairments. Moderate dementia was found in one patient with early meningovascular neurosyphilis and one patient with progressive paralysis. This article considers a clinical case of a female patient with early syphilitic meningitis who had a baby with congenital syphilis.


2016 ◽  
Vol 41 (5-6) ◽  
pp. 292-302 ◽  
Author(s):  
Claudia Woolf ◽  
Melissa J. Slavin ◽  
Brian Draper ◽  
Floortje Thomassen ◽  
Nicole A. Kochan ◽  
...  

Background: The Clinical Dementia Rating Scale (CDR) is used to rate dementia severity. Its utility in diagnosing mild cognitive impairment (MCI) and its predictive value remain unknown. Aims: The aim of this study was to examine the association between CDR scores and expert MCI diagnosis, and to determine whether baseline CDR scores were predictive of cognitive or functional decline and progression to dementia over 6 years. Methods: At baseline, the sample comprised 733 non-demented participants aged 70-90 years from the longitudinal Sydney Memory and Ageing Study. Global and sum of boxes CDR scores were obtained at baseline. Participants also received comprehensive neuropsychological and functional assessment as well as expert consensus diagnoses at baseline and follow-up. Results: At baseline, CDR scores had high specificity but low sensitivity for broadly defined MCI. The balance of sensitivity and specificity improved for narrowly defined MCI. Longitudinally, all baseline CDR scores predicted functional change and dementia, but CDR scores were not predictive of cognitive change. Conclusion: CDR scores do not correspond well with MCI, except when MCI is narrowly defined, suggesting that the CDR taps into the more severe end of MCI. All CDR scores usefully predict functional decline and incident dementia.


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