Clinical manifestations of neurosyphilis in women of reproductive age

2016 ◽  
Vol 7 (2) ◽  
pp. 57-62
Author(s):  
Maria L Chuhlovina ◽  
Denis V Zaslavsky ◽  
Ekaterina A Bichun
Keyword(s):  
Rating Scale ◽  
Congenital Syphilis ◽  
Clinical Manifestations ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Clinical Dementia Rating ◽  
Clock Drawing Test ◽  
Mattis Dementia Rating Scale ◽  
Moderate Dementia ◽  
Dementia Rating Scale

The research objective is investigation of clinical manifestations of neurosyphilis in women of reproductive age. The diagnoses were based on complaints, anamnestic information, neurological examinations, dermatovenerology consultations, serological blood and liquor tests. All the patients underwent psychometric tests. The following methods were used: mini-mental state examination (MMSE), “Frontal Assessment Battery”, Clinical Dementia Rating scale, Clock drawing test, “Information-Memory-Consideration Concentration” test, Mattis Dementia Rating Scale. Nine patients with early neurosyphilis (between the ages of 18 to 40) and eight patients with late neurosyphilis (between the ages of 28 to 43) were surveyed. Syphilitic meningitis (six cases), meningovascular neurosyphilis (three cases) were found in patients with early neurosyphilis. As for the patients with late neurosyphilis, two of them were diagnosed to have syphilitic meningitis, two patients had meningovascular neurosyphilis, two had progressive paralysis, tabes dorsalis was identified in one patient, one had taboparalysis. Only three patients showed specific skin and mucic manifestations. The patients at all the stages of neurosyphilis demonstrated mild cognitive impairments. Moderate dementia was found in one patient with early meningovascular neurosyphilis and one patient with progressive paralysis. This article considers a clinical case of a female patient with early syphilitic meningitis who had a baby with congenital syphilis.

scholarly journals The Bayer: Activities of Daily Living Scale (B-ADL) in the differentiation between mild to moderate dementia and normal aging

2007 ◽  
Vol 29 (4) ◽  
pp. 350-353 ◽  
Author(s):  
Jefferson C Folquitto ◽  
Sonia E Z Bustamante ◽  
Sérgio B Barros ◽  
Dionisio Azevedo ◽  
Marcos A Lopes ◽  
...  
Keyword(s):  
Activities Of Daily Living ◽  
Mental State ◽  
Daily Living ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Clinical Dementia Rating ◽  
Mild Dementia ◽  
Moderate Dementia ◽  
Dementia Rating Scale ◽  
State Examination

OBJECTIVES: To investigate the applicability of the Bayer - Activities of Daily Living scale and its efficiency in differentiating individuals with mild to moderate dementia from normal elderly controls. METHOD: We selected 33 patients with diagnosis of mild to severe dementia, according to ICD-10 criteria, and 59 controls. All the subjects were evaluated with the Mini-Mental State Examination and the Clinical Dementia Rating Scale and the Bayer - Activities of Daily Living scale was applied to informants. RESULTS: The internal consistency of the Bayer - Activities of Daily Living was high (Cronbach's alpha = 0.981). Mean Mini-Mental State Examination and Bayer - Activities of Daily Living scores of demented patients and controls were significantly different (p < 0.001). Mean Mini-Mental State Examination and Bayer - Activities of Daily Living scores were significantly different between Clinical Dementia Rating Scale 0 (controls; n = 59) versus Clinical Dementia Rating Scale 1 (mild dementia; n = 15), Clinical Dementia Rating Scale 0 versus Clinical Dementia Rating Scale 2 (moderate dementia; n = 13), and for Clinical Dementia Rating Scale 1 versus Clinical Dementia Rating Scale 2 (p < 0.003). DISCUSSION: The Bayer - Activities of Daily Living scale and Mini-Mental State Examination differentiated elderly controls from patients with mild or moderate dementia, and patients with mild dementia from those with moderate dementia. CONCLUSIONS: The results suggest that the Bayer - Activities of Daily Living scale applied to an informant can help in the diagnosis and follow-up of Brazilian patients with mild to moderate dementia.

scholarly journals Comparison of clinical dementia rating scale and clock drawing test in elderly without dementia

2017 ◽  
Vol 1 (3) ◽  
pp. 57-67
Author(s):  
A Shamsollah ◽  
A Farhadinasab ◽  
S Noorbakhsh ◽  
◽  
◽  
...  
Keyword(s):  
Rating Scale ◽  
Clinical Dementia Rating ◽  
Clock Drawing Test ◽  
Clock Drawing ◽  
Drawing Test ◽  
Dementia Rating Scale

scholarly journals Disease Progression in Frontotemporal Dementia and Alzheimer Disease: The Contribution of Staging Scales

2020 ◽  
pp. 089198872094423
Author(s):  
Thaís Bento Lima-Silva ◽  
Eneida Mioshi ◽  
Valéria Santoro Bahia ◽  
Mário Amore Cecchini ◽  
Luciana Cassimiro ◽  
...  
Keyword(s):  
Alzheimer Disease ◽  
Disease Progression ◽  
Frontotemporal Dementia ◽  
Rating Scale ◽  
Severe Disease ◽  
Primary Progressive Aphasia ◽  
Behavioral Changes ◽  
Clinical Dementia Rating ◽  
Dementia Rating Scale ◽  
Disease Stages

Introduction: There is a shortage of validated instruments to estimate disease progression in frontotemporal dementia (FTD). Objectives: To evaluate the ability of the FTD Rating Scale (FTD-FRS) to detect functional and behavioral changes in patients diagnosed with the behavioral variant of FTD (bvFTD), primary progressive aphasia (PPA), and Alzheimer disease (AD) after 12 months of the initial evaluation, compared to the Clinical Dementia Rating scale−frontotemporal lobar degeneration (CDR-FTLD) and the original Clinical Dementia Rating scale (CDR). Methods: The sample consisted of 70 individuals, aged 40+ years, with at least 2 years of schooling, 31 with the diagnosis of bvFTD, 12 with PPA (8 with semantic variant and 4 with non-fluent variant), and 27 with AD. The FTD-FRS, the CDR, and the 2 additional CDR-FTLD items were completed by a clinician, based on the information provided by the caregiver with frequent contact with the patient. The Addenbrooke Cognitive Examination-Revised was completed by patients. After 12 months, the same protocol was applied. Results: The FTD-FRS, CDR-FTLD, and CDR detected significant decline after 12 months in the 3 clinical groups (exception: FTD-FRS for PPA). The CDR was less sensitive to severe disease stages. Conclusions: The FTD-FRS and the CDR-FTLD are especially useful tools for dementia staging in AD and in the FTD spectrum.

scholarly journals Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale‐2 in Parkinson's disease

2018 ◽  
Vol 34 (2) ◽  
pp. 285-291 ◽  
Author(s):  
Taylor R. Hendershott ◽  
Delphine Zhu ◽  
Seoni Llanes ◽  
Cyrus P. Zabetian ◽  
Joseph Quinn ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Rating Scale ◽  
Comparative Sensitivity ◽  
Mattis Dementia Rating Scale ◽  
Dementia Rating Scale

The agreement of the Mattis Dementia Rating Scale with the Mini-Mental State Examination

2002 ◽  
Vol 17 (7) ◽  
pp. 685-686 ◽  
Author(s):  
W. Freidl ◽  
W.-J. Stronegger ◽  
A. Berghold ◽  
B. Reinhart ◽  
K. Petrovic ◽  
...  
Keyword(s):  
Mental State ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Mattis Dementia Rating Scale ◽  
Dementia Rating Scale ◽  
State Examination

THE NATURE OF REPRODUCTIVE DISORDERS IN WOMEN WITH HYPERANDROGENISM SYNDROMEq

2021 ◽  
Vol 2 (4) ◽  
pp. 13-16
Author(s):  
M. M Asatova ◽  
◽  
S. M. Safoeva
Keyword(s):  
Laboratory Data ◽  
Clinical Manifestations ◽  
Reproductive Age ◽  
Reproductive Disorders ◽  
Menstrual Disorders ◽  
Women Of Reproductive Age ◽  
Perinatal Center ◽  
Androgen Secretion ◽  
The City ◽  
Anovulatory Infertility

PCOS occupies a leading place in the population of women with clinical manifestations of excessive androgen secretion and is detected in 72.1-82% of cases, while among women with anovulatory infertility-in 55-91% of cases (Lizneva D. (2016). The criteria, prevalence and phenotypes of PCOS. Fertil.Steril., 106 (1), 6-15). The article discusses the results of a study conducted based on the City Perinatal Center of Tashkent to study the frequency and nature of reproductive disorders in women with symptoms of hyperandrogenism. The study involved women of reproductive age with various menstrual disorders and infertility. The analysis of anamnestic, subjective and objective, clinical and laboratory data of patients was carried out

Facets of the problem of infiltrative endometriosis: from pathogenesis to effective therapy

GYNECOLOGY ◽  
2021 ◽  
Vol 23 (2) ◽  
pp. 117-124
Author(s):  
Viktor E. Radzinskii ◽  
Mekan R. Orazov ◽  
Ljudmila M. Mihaleva ◽  
Madina A. Bekulova
Keyword(s):  
Pelvic Pain ◽  
Economic Burden ◽  
Clinical Manifestations ◽  
Effective Therapy ◽  
Reproductive Age ◽  
Personal Life ◽  
Depression And Anxiety ◽  
Women Of Reproductive Age ◽  
Unresolved Problem ◽  
High Prevalence

Endometriosis remains an unresolved problem in gynecology. The urgency of the fight against this disease is due to its high prevalence among women of reproductive age. Endometriosis, especially its infiltration forms, affects all aspects of the patients life, its clinical manifestations pelvic pain, dyspareunia, dysmenorrhea, dyschezia, lead to social disadaptation, problems in personal life, depression and anxiety. The socio-economic burden of the disease motivates researchers to further study the pathogenesis of endometriosis and search for pathogenetically justified pharmacological solutions.

scholarly journals A-035 What Make Them Tick? The Clock Drawing Test and Correlations Between Cognitive and Functional Abilities

2020 ◽  
Vol 35 (6) ◽  
pp. 825-825
Author(s):  
Gold D ◽  
Boulos K ◽  
Coolbrith N ◽  
Piryatinsky I
Keyword(s):  
Cognitive Abilities ◽  
Rating Scale ◽  
Digit Span ◽  
Strongly Correlated ◽  
Cognitive Measures ◽  
Clock Drawing Test ◽  
Clock Drawing ◽  
Mattis Dementia Rating Scale ◽  
Drawing Test ◽  
Error Types

Abstract Objective The Clock Drawing Test (CDT) is among the most researched cognitive measures and is frequently used to screen for neurocognitive disorders (NCDs). No study to date has investigated the relationship between qualitative errors on the CDT and independence in instrumental activities of daily living (IADLs) or discrete cognitive abilities. Therefore, this study sought to evaluate the correlations between qualitative errors on the CDT and IADL status as well as performance in individual cognitive domains. Method Data were retrospectively collected from patients seen at an outpatient clinic in eastern Massachusetts, including 16 healthy controls, 22 patients with mild NCD, and 35 patients with major NCD. Analyses were performed between qualitative errors on the CDT and patients’ scores on the Lawton IADL Scale, Mattis Dementia Rating Scale-2 (DRS-2), Digit Span Forward and Backward, Trail Making Test (TMT), and the Boston Naming Test (BNT). Results IADL scores were moderately correlated with CDT error types. DRS-2 scores were strongly correlated commission of qualitative errors. Strong to very strong correlations were observed between TMT parts A & B scores and all qualitative error types. BNT performance was strongly correlated with conceptual deficits and spatial/planning errors. Digit Span Forward and Backward scores showed low correlations with all CDT errors. Conclusions Functional status appears only moderately correlated with commission of various CDT errors; however, several cognitive measures showed high correlation with various CDT error types. These findings suggest that certain qualitative errors may be indicative of cognitive impairments warranting further workup. Clinical implications and future directions are discussed.

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