The FTLD-modified Clinical Dementia Rating scale is a reliable tool for defining disease severity in Frontotemporal Lobar Degeneration: evidence from a brain SPECT study

2009 ◽  
Vol 17 (5) ◽  
pp. 703-707 ◽  
Author(s):  
B. Borroni ◽  
C. Agosti ◽  
E. Premi ◽  
C. Cerini ◽  
M. Cosseddu ◽  
...  
Keyword(s):  
Disease Severity ◽  
Frontotemporal Lobar Degeneration ◽  
Rating Scale ◽  
Brain Spect ◽  
Clinical Dementia Rating ◽  
Reliable Tool ◽  
Dementia Rating Scale

scholarly journals Translation, cross-cultural adaptation and applicability of the Brazilian version of the Frontotemporal Dementia Rating Scale (FTD-FRS)

2013 ◽  
Vol 7 (4) ◽  
pp. 387-396 ◽  
Author(s):  
Thais Bento Lima-Silva ◽  
Valéria Santoro Bahia ◽  
Viviane Amaral Carvalho ◽  
Henrique Cerqueira Guimarães ◽  
Paulo Caramelli ◽  
...  
Keyword(s):  
Frontotemporal Dementia ◽  
Disease Severity ◽  
Cultural Adaptation ◽  
Rating Scale ◽  
Cross Cultural ◽  
Clinical Dementia Rating ◽  
Cross Cultural Adaptation ◽  
Brazilian Version ◽  
Back Translation ◽  
Dementia Rating Scale

ABSTRACT Background: Staging scales for dementia have been devised for grading Alzheimer's disease (AD) but do not include the specific symptoms of frontotemporal lobar degeneration (FTLD). Objective: To translate and adapt the Frontotemporal Dementia Rating Scale (FTD-FRS) to Brazilian Portuguese. Methods: The cross-cultural adaptation process consisted of the following steps: translation, back-translation (prepared by independent translators), discussion with specialists, and development of a final version after minor adjustments. A pilot application was carried out with 12 patients diagnosed with bvFTD and 11 with AD, matched for disease severity (CDR=1.0). The evaluation protocol included: Addenbrooke's Cognitive Examination-Revised (ACE-R), Mini-Mental State Examination (MMSE), Executive Interview (EXIT-25), Neuropsychiatric Inventory (NPI), Frontotemporal Dementia Rating Scale (FTD-FRS) and Clinical Dementia Rating scale (CDR). Results: The Brazilian version of the FTD-FRS seemed appropriate for use in this country. Preliminary results revealed greater levels of disability in bvFTD than in AD patients (bvFTD: 25% mild, 50% moderate and 25% severe; AD: 36.36% mild, 63.64% moderate). It appears that the CDR underrates disease severity in bvFTD since a relevant proportion of patients rated as having mild dementia (CDR=1.0) in fact had moderate or severe levels of disability according to the FTD-FRS. Conclusion: The Brazilian version of the FTD-FRS seems suitable to aid staging and determining disease progression.

scholarly journals Disease Progression in Frontotemporal Dementia and Alzheimer Disease: The Contribution of Staging Scales

2020 ◽  
pp. 089198872094423
Author(s):  
Thaís Bento Lima-Silva ◽  
Eneida Mioshi ◽  
Valéria Santoro Bahia ◽  
Mário Amore Cecchini ◽  
Luciana Cassimiro ◽  
...  
Keyword(s):  
Alzheimer Disease ◽  
Disease Progression ◽  
Frontotemporal Dementia ◽  
Rating Scale ◽  
Severe Disease ◽  
Primary Progressive Aphasia ◽  
Behavioral Changes ◽  
Clinical Dementia Rating ◽  
Dementia Rating Scale ◽  
Disease Stages

Introduction: There is a shortage of validated instruments to estimate disease progression in frontotemporal dementia (FTD). Objectives: To evaluate the ability of the FTD Rating Scale (FTD-FRS) to detect functional and behavioral changes in patients diagnosed with the behavioral variant of FTD (bvFTD), primary progressive aphasia (PPA), and Alzheimer disease (AD) after 12 months of the initial evaluation, compared to the Clinical Dementia Rating scale−frontotemporal lobar degeneration (CDR-FTLD) and the original Clinical Dementia Rating scale (CDR). Methods: The sample consisted of 70 individuals, aged 40+ years, with at least 2 years of schooling, 31 with the diagnosis of bvFTD, 12 with PPA (8 with semantic variant and 4 with non-fluent variant), and 27 with AD. The FTD-FRS, the CDR, and the 2 additional CDR-FTLD items were completed by a clinician, based on the information provided by the caregiver with frequent contact with the patient. The Addenbrooke Cognitive Examination-Revised was completed by patients. After 12 months, the same protocol was applied. Results: The FTD-FRS, CDR-FTLD, and CDR detected significant decline after 12 months in the 3 clinical groups (exception: FTD-FRS for PPA). The CDR was less sensitive to severe disease stages. Conclusions: The FTD-FRS and the CDR-FTLD are especially useful tools for dementia staging in AD and in the FTD spectrum.

scholarly journals P2-103: Korean version of Mini-Mental State Examination and Clinical Dementia Rating Scale Sum of Boxes scores in staging the dementia

2009 ◽  
Vol 5 (4S_Part_10) ◽  
pp. P292-P292 ◽  
Author(s):  
Hee Jin Kang ◽  
Young-Hee Chang ◽  
Ha-Ry Na ◽  
Min Jae Baek ◽  
Hyun Jung Kim ◽  
...  
Keyword(s):  
Mental State ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Clinical Dementia Rating ◽  
Korean Version ◽  
Dementia Rating Scale ◽  
State Examination

Interchanging Scores Between Clinical Dementia Rating Scale and Global Deterioration Scale

2003 ◽  
Vol 17 (2) ◽  
pp. 98-105 ◽  
Author(s):  
Seong Hye Choi ◽  
Byung Hwa Lee ◽  
Seonwoo Kim ◽  
Dong Seok Hahm ◽  
Jee Hyang Jeong ◽  
...  
Keyword(s):  
Rating Scale ◽  
Clinical Dementia Rating ◽  
Global Deterioration Scale ◽  
Dementia Rating Scale

Clinical manifestations of neurosyphilis in women of reproductive age

2016 ◽  
Vol 7 (2) ◽  
pp. 57-62
Author(s):  
Maria L Chuhlovina ◽  
Denis V Zaslavsky ◽  
Ekaterina A Bichun
Keyword(s):  
Rating Scale ◽  
Congenital Syphilis ◽  
Clinical Manifestations ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Clinical Dementia Rating ◽  
Clock Drawing Test ◽  
Mattis Dementia Rating Scale ◽  
Moderate Dementia ◽  
Dementia Rating Scale

The research objective is investigation of clinical manifestations of neurosyphilis in women of reproductive age. The diagnoses were based on complaints, anamnestic information, neurological examinations, dermatovenerology consultations, serological blood and liquor tests. All the patients underwent psychometric tests. The following methods were used: mini-mental state examination (MMSE), “Frontal Assessment Battery”, Clinical Dementia Rating scale, Clock drawing test, “Information-Memory-Consideration Concentration” test, Mattis Dementia Rating Scale. Nine patients with early neurosyphilis (between the ages of 18 to 40) and eight patients with late neurosyphilis (between the ages of 28 to 43) were surveyed. Syphilitic meningitis (six cases), meningovascular neurosyphilis (three cases) were found in patients with early neurosyphilis. As for the patients with late neurosyphilis, two of them were diagnosed to have syphilitic meningitis, two patients had meningovascular neurosyphilis, two had progressive paralysis, tabes dorsalis was identified in one patient, one had taboparalysis. Only three patients showed specific skin and mucic manifestations. The patients at all the stages of neurosyphilis demonstrated mild cognitive impairments. Moderate dementia was found in one patient with early meningovascular neurosyphilis and one patient with progressive paralysis. This article considers a clinical case of a female patient with early syphilitic meningitis who had a baby with congenital syphilis.

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