Post-operative pain relief following laparoscopic abdominal surgery: General anesthesia versus combination with regional anesthesia using intrathecal Morphine and Fentanyl

2011 ◽  
Vol 28 ◽  
pp. 201 ◽  
Author(s):  
D. Segal ◽  
A. Assalia ◽  
A. Weissman ◽  
R. Edry
2005 ◽  
Vol 12 (03) ◽  
pp. 340-345
Author(s):  
ROBINA FIRDOUS

The severity of post-operative pain and the lack of efforts in relievingit have led to the involvement of Anaesthesiologists in the management of post-operative and acute pain. Parenteralopiates have been utilized for post-operative pain management. The identification of the opioid receptors on substantiagelatinosa has provided an alternate route i.e 1 the epidural route - for administering opiates. Objectives: To evaluateand compare the efficacy and side effects of parenteral Buprenorphine with those of Extradural Buprenorphine.Setting: Department of Anaesthesia, District Headquarter Hospital, Faisalabad. Period: The data was collected duringthe last three and a half years. Materials and Methods: Sixty adult patients of either sex and ages ranging from 35-45years, who underwent lower abdominal surgery, were randomly selected for the study. They were equally divided intotwo groups. Group I patients were administered Buprenorphine 0.3 mg through the epidural catheter in extraduralspace. Group II patients were given Buprenorphine 0.3 mg intramuscularly. Results: Buprenorphine through theepidural route gives better analgesia with fewer side effects as compared with the parenteral route.


1980 ◽  
Vol 53 (3 Suppl) ◽  
pp. S218-S218 ◽  
Author(s):  
W. Nelson ◽  
J. Katz

2007 ◽  
Vol 5 (3) ◽  
pp. 0-0
Author(s):  
Povilas Miliauskas ◽  
Renatas Tikuišis ◽  
Saulius Cicėnas ◽  
Aleksas Žurauskas ◽  
Narimantas Evaldas Samalavičius

Povilas Miliauskas, Renatas Tikuišis, Saulius Cicėnas, Aleksas Žurauskas, Narimantas Evaldas SamalavičiusVilniaus universiteto Onkologijos institutas,Santariškių g. 1, LT-08660 VilniusEl paštas: [email protected] Įvadas / tikslas Šoninė torakotomija yra viena iš skausmingiausių operacijų. Šiame darbe nagrinėti ligonių, kuriems atliekamos plaučių operacijos, pooperacinio nuskausminimo aspektai. Buvo siekta palyginti intratekaliniu būdu ir į veną švirkščiamo morfino skausmo malšinamąjį efektyvumą po plaučių operacijos atliekant šoninę torakotomiją. Metodai Ligoniai, kuriems buvo atliekamos plaučių operacijos, atsitiktiniu būdu buvo suskirstyti į dvi grupes: IT – kuriems prieš operaciją intratekaliniu būdu sušvirkšta 0,5 mg morfino dozė (n = 40), ir IV – kuriems pooperaciniu laikotarpiu į veną buvo švirkščiama morfino 3 mg/val. (n = 40). Abiejų grupių ligoniai statistiškai nesiskyrė pagal lytį, amžių, svorį, fizinę būklę pagal ASA ir atliktas chirurgines operacijas. Pirmos paros pooperacinio nuskausminimo efektyvumas buvo vertinamas vizualinės analoginės skalės (VAS) skausmo balais ramybėje ir kosint. Papildomai ketorolako buvo švirkščiama ligoniui, jaučiančiam stiprius skausmus. Rezultatai VAS balai ramybėje ir kosint buvo daug mažesni IT grupės (ramybėje p < 0,05; kosint p < 0,05). Vidutinės papildomos ketorolako dozės vienam ligoniui buvo mažesnės IT grupėje (p < 0,05). Pooperacinis pykinimas, vėmimas ir kvėpavimo slopinimas buvo silpnesnis IT grupės pacientų. Išvados Skausmo malšinimas morfinu į intratekalinį tarpą yra pranašesnis už intraveninį nuskausminimą morfinu pirmą parą po šoninės torakotomijos. Pagrindiniai žodžiai: potorakotominis skausmas, intratekalinis skausmo malšinimas, intraveninis skausmo malšinimas Intrathecal morphine for post-thoracotomy pain relief Povilas Miliauskas, Renatas Tikuišis, Saulius Cicėnas, Aleksas Žurauskas, Narimantas Evaldas SamalavičiusVilnius University, Institute of Oncology,Santariškių str. 1, LT-08660 Vilnius, LithuaniaE-mail: [email protected] Background / objective Post-thoracotomy pain is one of the most severe types of post-operative pain. Intrathecal morphine has been shown to provide superior pain control within the first postoperative day compared with intravenous morphine after thoracotomy. Methods In this study, we compared the analgesic effect of lumbar intrathecal 0.5 mg morphine (IT group, n = 40) given before general anaesthesia and analgesia with intravenous morphine 3 mg/h (group IV, n = 40). Additionally, ketorolac was injected on request. The intensity of pain was assessed 2, 4, 8, 16 and 24 hours after extubation by visual analog scale (VAS = 1–10) at rest and on coughing. Results Analgesia at rest and while coughing was significantly better in the IT group on the first postoperative day. Ketorolac consumption was lower in the IT group. Nausea, vomiting and respiratory depression were more frequent in the IV group. Conclusions These results show that intrathecal analgesia compared with IV morphine improved pain control after thoracotomy on the first postoperative day. Keywords: post-thoracotomy pain, intrathecal analgesia, intravenous analgesia


Author(s):  
A. M. Morozov ◽  
A. N. Pichugova ◽  
E. M. Askerov ◽  
S. V. Zhukov ◽  
Yu. E. Minakova ◽  
...  

Topicality. Currently, intrapartum fetal health care is aimed at an adequate choice of anesthetic aid used during delivery to minimize the negative impact. Despite the wide range of currently existing anesthetics, the choice of anesthetic drug is limited by its negative effect not only on the fetus, but also on the contractile activity of the uterus, which significantly reduces the number of anesthetics used in obstetric practice.The purpose of this study is to analyze domestic and foreign literature in order to study the effect of anesthesia on the condition of the fetus. Material and methods. In the course of this study, an analysis of modern Russian and foreign literary sources, as well as the latest scientific works in the field of methods of general and regional anesthesia in the field of obstetrics and gynecology, was carried out.Results. Almost all drugs used for general anesthesia in obstetric practice can have a negative effect on the fetus. Neuroaxial pain relief methods are leading in obstetric practice, but their use is associated with complications that can lead to an adverse outcome not only from the mother, but also from the fetus. One such complication is the risk of arterial hypotension. It is interesting that comparative studies of general and regional anesthesia methods during operative delivery differ in the results obtained. Regarding the issue of anesthesia of natural births, the information of the Congress of the American Society of Anesthesiologists (lecture C.A. Wong (Chicago) “Neuroaxial Labor Analgesia and Prognancy Outcome: Factand Fiction”) remains relevant, according to which neuroaxial anesthesia methods do not affect the condition of the fetus, provided that the mother has stable hemodynamics.Conclusion. Due to the appearance and release of neuroaxial pain relief methods, completely unreasonably little attention is paid to the issues of general anesthesia of pregnant women, while according to the results of a study of scientific literary sources, it was revealed that this method of pain relief in obstetric practice is accompanied by the most direct and mediated effects on the fetus. Neuroaxial pain relief methods have practically no effect on the condition of the fetus, provided that the mother has stable hemodynamics.


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