INTRATHECAL MORPHINE FOR POST-OPERATIVE PAIN RELIEF

1980 ◽  
Vol 53 (3 Suppl) ◽  
pp. S218-S218 ◽  
Author(s):  
W. Nelson ◽  
J. Katz
2007 ◽  
Vol 5 (3) ◽  
pp. 0-0
Author(s):  
Povilas Miliauskas ◽  
Renatas Tikuišis ◽  
Saulius Cicėnas ◽  
Aleksas Žurauskas ◽  
Narimantas Evaldas Samalavičius

Povilas Miliauskas, Renatas Tikuišis, Saulius Cicėnas, Aleksas Žurauskas, Narimantas Evaldas SamalavičiusVilniaus universiteto Onkologijos institutas,Santariškių g. 1, LT-08660 VilniusEl paštas: [email protected] Įvadas / tikslas Šoninė torakotomija yra viena iš skausmingiausių operacijų. Šiame darbe nagrinėti ligonių, kuriems atliekamos plaučių operacijos, pooperacinio nuskausminimo aspektai. Buvo siekta palyginti intratekaliniu būdu ir į veną švirkščiamo morfino skausmo malšinamąjį efektyvumą po plaučių operacijos atliekant šoninę torakotomiją. Metodai Ligoniai, kuriems buvo atliekamos plaučių operacijos, atsitiktiniu būdu buvo suskirstyti į dvi grupes: IT – kuriems prieš operaciją intratekaliniu būdu sušvirkšta 0,5 mg morfino dozė (n = 40), ir IV – kuriems pooperaciniu laikotarpiu į veną buvo švirkščiama morfino 3 mg/val. (n = 40). Abiejų grupių ligoniai statistiškai nesiskyrė pagal lytį, amžių, svorį, fizinę būklę pagal ASA ir atliktas chirurgines operacijas. Pirmos paros pooperacinio nuskausminimo efektyvumas buvo vertinamas vizualinės analoginės skalės (VAS) skausmo balais ramybėje ir kosint. Papildomai ketorolako buvo švirkščiama ligoniui, jaučiančiam stiprius skausmus. Rezultatai VAS balai ramybėje ir kosint buvo daug mažesni IT grupės (ramybėje p < 0,05; kosint p < 0,05). Vidutinės papildomos ketorolako dozės vienam ligoniui buvo mažesnės IT grupėje (p < 0,05). Pooperacinis pykinimas, vėmimas ir kvėpavimo slopinimas buvo silpnesnis IT grupės pacientų. Išvados Skausmo malšinimas morfinu į intratekalinį tarpą yra pranašesnis už intraveninį nuskausminimą morfinu pirmą parą po šoninės torakotomijos. Pagrindiniai žodžiai: potorakotominis skausmas, intratekalinis skausmo malšinimas, intraveninis skausmo malšinimas Intrathecal morphine for post-thoracotomy pain relief Povilas Miliauskas, Renatas Tikuišis, Saulius Cicėnas, Aleksas Žurauskas, Narimantas Evaldas SamalavičiusVilnius University, Institute of Oncology,Santariškių str. 1, LT-08660 Vilnius, LithuaniaE-mail: [email protected] Background / objective Post-thoracotomy pain is one of the most severe types of post-operative pain. Intrathecal morphine has been shown to provide superior pain control within the first postoperative day compared with intravenous morphine after thoracotomy. Methods In this study, we compared the analgesic effect of lumbar intrathecal 0.5 mg morphine (IT group, n = 40) given before general anaesthesia and analgesia with intravenous morphine 3 mg/h (group IV, n = 40). Additionally, ketorolac was injected on request. The intensity of pain was assessed 2, 4, 8, 16 and 24 hours after extubation by visual analog scale (VAS = 1–10) at rest and on coughing. Results Analgesia at rest and while coughing was significantly better in the IT group on the first postoperative day. Ketorolac consumption was lower in the IT group. Nausea, vomiting and respiratory depression were more frequent in the IV group. Conclusions These results show that intrathecal analgesia compared with IV morphine improved pain control after thoracotomy on the first postoperative day. Keywords: post-thoracotomy pain, intrathecal analgesia, intravenous analgesia


2014 ◽  
Vol 11 (3) ◽  
pp. 246-249
Author(s):  
SN Singh ◽  
A Subedi ◽  
JN Prasad ◽  
MC Regmi

Background: Post-operative pain management can be challenging. Objectives: To compare the efficiency of morphine with that of butorphanol in controlling the postoperative pain relief. Methods: This double-blind randomized clinical trial was performed on 75 consecutive patients. Intrathecal 3ml hyperbaric bupivacaine mixed with morphine (200 microgm-0.25ml); or mixed with butorphanol (200 microgm-0.25ml); or mixed with normal saline 0.25ml was administered to alternate groups (25 patients in each group), for postoperative pain relief after abdominal and vaginal hysterectomy. They were monitored for pain relief in the recovery and gynaecological ward for 24 hours. If the patient had any complications like nausea, vomiting, itching and urinary retention were recorded. Results: Time for two segment regression of sensory level in patients receiving intrathecal morphine (Group-M), was 114.0±12.2 min., intrathecal butorphanol (Group- B) was 96.0+24.4 min and normal saline (Group- N) was 104.4 ± 18.5min. Duration of pain relief after subarachonoid block In Group-M was 492.0 ± 153.2min, in Group- B 311.20 ±58.7min and in Group-N it was 299.4 ± 72.7min. Two patients (8%) in Group-M had nausea, vomiting and itching but none in other groups. Urinary retention occurred in 3 patients (12%), in Group- M, whereas the same was found in 2 patients (8%) and 1 patient (4%) of Group-B and N respectively. Conclusion: Intrathecal morphine provided prolonged and better analgesic effect after abdominal and vaginal hysterectomy than butorphanol, though there were some side effects like nausea, vomiting, itching and urinary retention which were graded by the patients as clinically not significant. DOI: http://dx.doi.org/10.3126/hren.v11i3.9640 Health Renaissance 2013;11(3):246-249


2006 ◽  
Vol 102 (4) ◽  
pp. 1157-1163 ◽  
Author(s):  
Lesley De Pietri ◽  
Antonio Siniscalchi ◽  
Alexia Reggiani ◽  
Michele Masetti ◽  
Bruno Begliomini ◽  
...  

2011 ◽  
Vol 1 (2) ◽  
pp. 32 ◽  
Author(s):  
Mohammed Mohsin Uzzaman ◽  
Muhammed Rafay Sameem Siddiqui

The most commonly encountered complication after haemorrhoidectomy is post-operative pain. Relief of this pain may aid earlier recovery. A literature search was performed examining the different surgical and medical agents for the relief of post haemorrhoidectomy pain using Pubmed, MEDLINE, EMBASE, CINAHL and Cochrane library databases. Pain can be relieved by surgical or medical agents. Surgery incorporates a risk of incontinence. A number of studies examine the role of medical agents.A variety of surgical techniques and medical agents are available to the clinician in the treatment of post haemorrhoidectomy pain. Tailored management to individual patients should ensure appropriate symptomatic control and prompt recovery.


2005 ◽  
Vol 12 (03) ◽  
pp. 340-345
Author(s):  
ROBINA FIRDOUS

The severity of post-operative pain and the lack of efforts in relievingit have led to the involvement of Anaesthesiologists in the management of post-operative and acute pain. Parenteralopiates have been utilized for post-operative pain management. The identification of the opioid receptors on substantiagelatinosa has provided an alternate route i.e 1 the epidural route - for administering opiates. Objectives: To evaluateand compare the efficacy and side effects of parenteral Buprenorphine with those of Extradural Buprenorphine.Setting: Department of Anaesthesia, District Headquarter Hospital, Faisalabad. Period: The data was collected duringthe last three and a half years. Materials and Methods: Sixty adult patients of either sex and ages ranging from 35-45years, who underwent lower abdominal surgery, were randomly selected for the study. They were equally divided intotwo groups. Group I patients were administered Buprenorphine 0.3 mg through the epidural catheter in extraduralspace. Group II patients were given Buprenorphine 0.3 mg intramuscularly. Results: Buprenorphine through theepidural route gives better analgesia with fewer side effects as compared with the parenteral route.


Sign in / Sign up

Export Citation Format

Share Document