The impact on drug mass flow rate of interrupting and resuming carrier fluid flow: an in vitro study on a multi-lumen infusion device

Performance of generic rim seal configurations, axial-clearance rim seal (ACS), radial-clearance rim seal (RCS), radial-axial clearance rim seal (RACS) are compared under realistic working conditions. Conjugate heat transfer analysis on rim seal is performed in this paper to understand the impact of ingestion on disc temperature. Results show that seal effectiveness and cooling effectiveness of RACS are the best when compared with ACS and RCS, the minimum mass flow rate for seal of RACS is 75% of that of RCS, and 34.6% of ACS. Authors compare the disc temperature distribution between different generic rim seal configurations where the RACS seems to be favorable in terms of low disc temperature. In addition, RACS has higher air-cooled aerodynamic efficiency, minimizing the mainstream performance penalty when compared with ACS and RCS. Corresponding to the respective minimum mass flow rate for seal, the air-cooled aerodynamic efficiency of RACS is 23.71% higher than that of ACS, and 12.79% higher than the RCS.

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Investigating the impact of alpha/beta and LET d on relative biological effectiveness in scanned proton beams: An in vitro study based on human cell lines

Medical Physics ◽

10.1002/mp.14212 ◽

2020 ◽

Vol 47 (8) ◽

pp. 3691-3702 ◽

Cited By ~ 2

Author(s):

Elisabeth Mara ◽

Monika Clausen ◽

Suphalak Khachonkham ◽

Simon Deycmar ◽

Clara Pessy ◽

...

Keyword(s):

Cell Lines ◽

Human Cell ◽

Relative Biological Effectiveness ◽

In Vitro Study ◽

Vitro Study ◽

Human Cell Lines ◽

Biological Effectiveness ◽

Alpha Beta ◽

The Impact

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Effect of HFNC flow rate, cannula size, and nares diameter on generated airway pressures: An in vitro study

Pediatric Pulmonology ◽

10.1002/ppul.22636 ◽

2012 ◽

Vol 48 (5) ◽

pp. 506-514 ◽

Cited By ~ 60

Author(s):

Emidio M. Sivieri ◽

Jeffrey S. Gerdes ◽

Soraya Abbasi

Keyword(s):

Flow Rate ◽

In Vitro Study ◽

Vitro Study ◽

Airway Pressures

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On-Sun Performance Evaluation of Alternative High-Temperature Falling Particle Receiver Designs

Journal of Solar Energy Engineering ◽

10.1115/1.4041100 ◽

2018 ◽

Vol 141 (1) ◽

Cited By ~ 4

Author(s):

Clifford K. Ho ◽

Joshua M. Christian ◽

Julius E. Yellowhair ◽

Kenneth Armijo ◽

William J. Kolb ◽

...

Keyword(s):

Mass Flow Rate ◽

Mass Flow ◽

Flow Rate ◽

Thermal Efficiency ◽

Particle Temperature ◽

Free Fall ◽

Mass Flow Rates ◽

Mesh Structures ◽

Free Falling ◽

The Impact

This paper evaluates the on-sun performance of a 1 MW falling particle receiver. Two particle receiver designs were investigated: obstructed flow particle receiver versus free-falling particle receiver. The intent of the tests was to investigate the impact of particle mass flow rate, irradiance, and particle temperature on the particle temperature rise and thermal efficiency of the receiver for each design. Results indicate that the obstructed flow design increased the residence time of the particles in the concentrated flux, thereby increasing the particle temperature and thermal efficiency for a given mass flow rate. The obstructions, a staggered array of chevron-shaped mesh structures, also provided more stability to the falling particles, which were prone to instabilities caused by convective currents in the free-fall design. Challenges encountered during the tests included nonuniform mass flow rates, wind impacts, and oxidation/deterioration of the mesh structures. Alternative materials, designs, and methods are presented to overcome these challenges.

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