Muscle strength and fatigue during isokinetic exercise in individuals with multiple sclerosis

Background and Purpose. Walking capacity is reduced in subjects with multiple sclerosis (MS). To develop effective exercise interventions to enhance walking capacity, it is important to determine the impact of factors, modifiable by exercise intervention (maximal muscle strength versus muscle oxidative capacity), on walking capacity. The purpose of this pilot study is to discriminate between the impact of maximal muscle strength versus muscle oxidative capacity on walking capacity in subjects with MS.Methods. From 24 patients with MS, muscle oxidative capacity was determined by calculation of exercise-onset oxygen uptake kinetics (mean response time) during submaximal exercise bouts. Maximal muscle strength (isometric knee extension and flexion peak torque) was assessed on dynamometer. All subjects completed a 6-minute walking test. Relationships between walking capacity (as a percentage of normal value) and muscle strength (of knee flexors and extensors) versus muscle oxidative capacity were assessed in multivariate regression analyses.Results. The expanded disability status score (EDSS) showed a significant univariate correlation (r=-0.70,P<0.004) with walking capacity. In multivariate regression analyses, EDSS and mean response time, but not muscle strength, were independently related to walking capacity (P<0.05).Conclusions. Walking distance is, next to disability level and not taking neurologic symptoms/deficits into account, primarily related to muscle oxidative capacity in subjects with MS. Additional study is needed to further examine/verify these findings.

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Effects of long-term resistance training and simultaneous electro-stimulation on muscle strength and functional mobility in multiple sclerosis

Multiple Sclerosis Journal ◽

10.1177/1352458510391339 ◽

2010 ◽

Vol 17 (4) ◽

pp. 468-477 ◽

Cited By ~ 68

Author(s):

Tom Broekmans ◽

Machteld Roelants ◽

Peter Feys ◽

Geert Alders ◽

Domien Gijbels ◽

...

Keyword(s):

Multiple Sclerosis ◽

Resistance Training ◽

Muscle Strength ◽

Controlled Trial ◽

Knee Extensor ◽

Functional Mobility ◽

Knee Extensors ◽

Strength Analysis ◽

Control Group

Background: Resistance training studies in multiple sclerosis (MS) often use short intervention periods. Furthermore, training efficiency could be optimized by unilateral training and/or electrical stimulation. Objective: To examine the effect(s) of unilateral long-term (20 weeks) standardized resistance training with and without simultaneous electro-stimulation on leg muscle strength and overall functional mobility. Methods: A randomized controlled trial involving 36 persons with MS. At baseline (PRE) and after 10 (MID) and 20 (POST) weeks of standardized (ACSM) light to moderately intense unilateral leg resistance training (RESO, n = 11) only or resistance training with simultaneous electro-stimulation (RESE, n = 11, 100 Hz, biphasic symmetrical wave, 400 µs), maximal isometric strength of the knee extensors and flexors (45°, 90° knee angle) and dynamic (60–180°/s) knee-extensor strength was measured and compared with a control group (CON, n = 14). Functional mobility was evaluated using the Timed Get Up and Go, Timed 25 Foot Walk, Two-Minute Walk Test, Functional Reach and Rivermead Mobility Index. Results: Maximal isometric knee extensor (90°, MID: +10 ± 3%, POST: +10 ± 4%) in RESO and knee flexor (45°, POST: +7 ± 4%; 90°, POST: +9 ± 5%) in RESE strength increased ( p < 0.05) compared with CON but RESO and RESE did not differ. Also, impaired legs responded positively to resistance training (unilateral leg strength analysis) and functional reaching increased significantly in RESO (+18%) compared with CON. Dynamic muscle strength and the remaining functional mobility tests did not change. Conclusion: Long-term light to moderately intense resistance training improves muscle strength in persons with MS but simultaneous electro-stimulation does not further improve training outcome.

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Multiple Sclerosis: Improving Quality of Life with Yoga

International Journal of Physical Education Fitness and Sports ◽

10.34256/ijpefs2128 ◽

2021 ◽

pp. 69-72

Author(s):

Kimberly Moore ◽

Colin G. Pennington

Keyword(s):

Quality Of Life ◽

Multiple Sclerosis ◽

Muscle Strength ◽

Individuals With Disabilities ◽

Personal Trainers ◽

Personal Fitness ◽

Specific Disability ◽

Mental Stressors ◽

And Training

Adaptive personal fitness and training classes are becoming more available in society. Incorporating modified classes allows for greater inclusion of individuals with disabilities. Personal fitness classes increase over health, muscle strength and decreases mental stressors. Unfortunately, personal trainers are taught modification for injuries, obesity, joint problems and not typically disabilities. Adhering toward generalized public and as inclusive towards individuals with disabilities. This leads to lack of knowledge in allowing individuals specifically with multiple sclerosis into training classes due to not knowing how to work with this specific disability. The purpose of this article is to describe what multiple sclerosis is and how yoga can be beneficial in enhancing everyday life and decreasing fatigue in individuals with Multiple Sclerosis.

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