RAPID DETECTION OF GROUP A STREPTOCOCCAL PHARYNGITIS IN A PEDIATRIC POPULATION WITH OPTICAL IMMUNOASSAY

1994 ◽  
Vol 13 (8) ◽  
pp. 742 ◽  
Author(s):  
Phyllis Della-Latta ◽  
Susan Whittier ◽  
Marion Hosmer ◽  
Fred Agre
2002 ◽  
Vol 35 (3) ◽  
pp. 250-257 ◽  
Author(s):  
Jacqueline E. Ehrlich ◽  
Byron P. Demopoulos ◽  
Kenneth R. Daniel ◽  
M.Christina Ricarte ◽  
Sherry Glied

PEDIATRICS ◽  
1991 ◽  
Vol 87 (5) ◽  
pp. 598-603
Author(s):  
Michael A. Gerber ◽  
Martin F. Randolph ◽  
Nancy J. Martin ◽  
Munir F. Rizkallah ◽  
P. Patrick Cleary ◽  
...  

Although several outbreaks of group G β-hemolytic streptococcal (GGBHS) pharyngitis have been described, doubt still remains regarding the etiologic role of GGBHS in acute pharyngitis beyond a limited number of situations. In the winter/spring of 1986/87, throat cultures were obtained from 222 consecutive children seen at a private pediatric office with acute pharyngitis and group A β-hemolytic streptococci (GABHS) were recovered from 91 children (41%) and GGBHS from 56 children (25%). One patient had both GABHS and GGBHS isolated. This isolation rate of GGBHS was dramatically greater than in previous and subsequent years, and 67% of the GGBHS isolates occurred during an 8-week period. Results of DNA fingerprinting of the 57 isolates of GGBHS demonstrated that 43 (75%) appeared to be the same strain. The patients with GGBHS were comparable to those with GABHS with respect to clinical findings, antistreptolysin-O titer response, and clinical response to antibiotic therapy. However, patients with GGBHS were significantly older (P < .05). This is the first well-documented, community-wide outbreak of GGBHS pharyngitis and the first respiratory outbreak of GGBHS pharyngitis in a pediatric population. GGBHS may be a more important cause of acute, treatable pharyngitis than had been previously recognized.


Author(s):  
Hamidreza Sherkatolabbasieh ◽  
Majid Firouzi ◽  
Shiva Shafizadeh ◽  
Iman Amiri

Background: The aim of this study is to evaluate the prevalence of group A beta-hemolytic pharyngitis by assessing the outcome of the culture and the resistance and sensitivity of group A beta hemolytic streptococcus to antibiotics. Methods: This cross-sectional study was conducted on 170 patients, aged 3-15 years, referred to the clinic with complaints of sore throat. Patients’ history was collected and physical examination was performed and were score based on clinical findings. Patients with other underlying pathologies and those taking antibiotics prior to the study were excluded from our study. Antimicrobial susceptibility test was performed by disk diffusion method against cephalexin, cefazolin, erythromycin and amoxicillin. Results: A total of 170 patients were reported with sore throat. Patients with positive culture results were 60% male and 40% female. Amoxicillin resistance was the greatest (5%) in the culture. All isolated bacteria were sensitive to amoxicillin, cephalexin, cefazolin and erythromycin. Patients with McIssac score ≥ 6 showed clinical sensitivity 75% specificity 61% negative predictive value 94.8% and positive predictive value 20.3% for Group A beta-hemolytic streptococcal pharyngitis. Conclusion: The results showed the higher the clinical score, the greater the chance of positive throat culture.


1990 ◽  
Vol 149 (4) ◽  
pp. 256-258 ◽  
Author(s):  
P. Egger ◽  
C. A. Siegrist ◽  
G. Strautmann ◽  
D. Belli ◽  
R. Auckenthaler

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