A prospective study of neonatal sepsis and meningitis in Southern Israel

1997 ◽  
Vol 16 (8) ◽  
pp. 768-773 ◽  
Author(s):  
DAVID GREENBERG ◽  
ERIC S. SHINWELL ◽  
PABLO YAGUPSKY ◽  
SHRAGIT GREENBERG ◽  
EUGENE LEIBOVITZ ◽  
...  
Keyword(s):  
Prospective Study ◽  
Neonatal Sepsis ◽  
A Prospective Study

Pulmonary hypertension in late onset neonatal sepsis using functional echocardiography: a prospective study

2021 ◽  
Author(s):  
Sujata Deshpande ◽  
Pradeep Suryawanshi ◽  
Shrikant Holkar ◽  
Yogen Singh ◽  
Rameshwor Yengkhom ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Prospective Study ◽  
Neonatal Sepsis ◽  
Late Onset ◽  
A Prospective Study

scholarly journals Serum Procalcitonin and C Reactive Protein in as early markers neonatal sepsis- A prospective study

2020 ◽  
Vol 8 (2) ◽  
pp. 73-77
Keyword(s):  
Blood Culture ◽  
Prospective Study ◽  
Gestational Age ◽  
Neonatal Sepsis ◽  
Statistical Significance ◽  
Developed Countries ◽  
Early Onset Sepsis ◽  
The Developed Countries ◽  
One Year ◽  
A Prospective Study

Neonatal sepsis is one of the commonest causes of morbidity and mortality in neonates in India compared to the developed countries. Aim: To evaluate the Procalcitonin level this is an early marker in the diagnosis of neonatal sepsis and to assess the suitability of this test in the diagnosis of early-onset sepsis. Method: The prospective study was conducted in the Neonatal Division of Department of Pediatrics, Prathima Institute of Medical Sciences over a period of one year. The blood samples from 100 babies meeting the inclusion and exclusion criteria constituted the material for study. Result: Among the n=100 cases n=39 were procalcitonin positive, compared with gestational age 10 (43.5%) cases were positive with a gestation of <37 weeks and 24 (31.2%) cases positive of cases >37 weeks and there was no statistical significance concerning gestational age the association of material characteristics with procalcitonin positive and CRP positive levels. Blood culture was positive in n=9 (9%) of babies with (90% CI, 5.3-14.9) and negative in n=91 (91%) of babies with (90% CI, 85.2-94.7). Conclusion: A positive blood culture is the only definitive and gold standard for confirming a case of sepsis. Since the culture and sensitivity test requires a minimum period of 48 hours which is a precious time in deciding on the treatment of sepsis in the newborn. Rapid diagnosis by using Procalcitonin and CRP gives a reasonable degree of accuracy in diagnosing neonatal sepsis and will also guide antibiotic therapy. Procalcitonin in comparison with CRP has better sensitivity and hence can detect most cases of neonatal sepsis and better negative predictive value.

scholarly journals Investigations on the Aetiology and Antibiotic Management of Neonatal Septicemia

2019 ◽  
Vol 28 (5-6) ◽  
pp. 105-15
Author(s):  
Hans Eldih Monintja
Keyword(s):  
Prospective Study ◽  
Neonatal Sepsis ◽  
Standard Treatment ◽  
Case Fatality ◽  
Third Generation ◽  
Neonatal Septicemia ◽  
E Coli ◽  
The Third ◽  
Antibiotic Management ◽  
A Prospective Study

This is a prospective study aimed in identifying the latest aetiological factors of neonatal sepsis in Dr. Cipto General Hospital, Jakarta, and investigating the efficacy of antibiotics treatment especially with ceftriaxone. This study revealed that the present main causative microorganisms are as follows: Pseudomonas, Klebsiella and E. coli. The case fatality rates being: (1) Standard treatment with ampicillin and gentamycin: 80.9%, (2) S(andard treatment with consomittant ceftriaxone: 20%, (3) Ceftriaxone: 9,52%. It seems that in facing neonatal septicemia, the initial antibiotic should be the third generation cephalosporine. The second choice is chloramphenicol. However, the causative agent and the sensitivity test should be monitored regularly.

scholarly journals Prevalence and Severity of Thrombocytopenia in Blood Culture Proven Neonatal Sepsis: A Prospective Study

2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Ramesh Bhat Y. ◽  
Phalguna Kousika ◽  
Leslie Lewis ◽  
Jayashree Purkayastha
Keyword(s):  
Blood Culture ◽  
Prospective Study ◽  
Neonatal Sepsis ◽  
A Prospective Study

scholarly journals Investigation on Immunoglobulin Fortification in Preventing Infections in the Newborn

2018 ◽  
Vol 29 (5-6) ◽  
pp. 91-6 ◽  
Author(s):  
Hans Eldih Monintja
Keyword(s):  
Prospective Study ◽  
Neonatal Sepsis ◽  
Newborn Infants ◽  
Control Group ◽  
A Prospective Study

Observations in neonatal sepsis revealed that the lgG concentrations in septic newborns is significantly lower than in non septic infants. This condition lead the author to investigate the role of fortification of lgG in infants with intrapartum infections. For this purpose a prospective study was carried out, 35 newborn infants with intrapartum infections were treated with lgG Cutter 0,6 mg per Kg BW per week and 35 other infants with similar criteria served as control group. The result of the trial showed that /gG administration could help in prevention of minor infections.

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