THE RELATIONSHIP OF MAXILLARY SINUSITIS TO INFECTION IN THE CONTIGUOUS SINUSES, MIDDLE EAR, AND LOWER RESPIRATORY TRACT

1936 ◽  
Vol 29 (10) ◽  
pp. 999-1002
Author(s):  
Paul L. Mahoney
Keyword(s):  
Respiratory Tract ◽  
Middle Ear ◽  
Lower Respiratory Tract ◽  
Maxillary Sinusitis ◽  
Relationship Of ◽  
The Relationship

The relationship of nasal disorders to lower respiratory tract symptoms and illness in a random sample of children

1992 ◽  
Vol 14 (2) ◽  
pp. 91-94 ◽  
Author(s):  
Marisa B. Barr ◽  
Scott T. Weiss ◽  
Mark R. Segal ◽  
Ira B. Tager ◽  
Frank E. Speizer
Keyword(s):  
Respiratory Tract ◽  
Random Sample ◽  
Lower Respiratory Tract ◽  
Relationship Of ◽  
The Relationship

scholarly journals Major evolutionary transitions and innovations: the tympanic middle ear

2017 ◽  
Vol 372 (1713) ◽  
pp. 20150483 ◽  
Author(s):  
Abigail S. Tucker
Keyword(s):  
Middle Ear ◽  
Morphological Diversity ◽  
The Novel ◽  
Evolutionary Transitions ◽  
Jaw Joint ◽  
Evolution Of Mammals ◽  
Key Steps ◽  
Evo Devo ◽  
Relationship Of ◽  
The Relationship

One of the most amazing transitions and innovations during the evolution of mammals was the formation of a novel jaw joint and the incorporation of the original jaw joint into the middle ear to create the unique mammalian three bone/ossicle ear. In this review, we look at the key steps that led to this change and other unusual features of the middle ear and how developmental biology has been providing an understanding of the mechanisms involved. This starts with an overview of the tympanic (air-filled) middle ear, and how the ear drum (tympanic membrane) and the cavity itself form during development in amniotes. This is followed by an investigation of how the ear is connected to the pharynx and the relationship of the ear to the bony bulla in which it sits. Finally, the novel mammalian jaw joint and versatile dentary bone will be discussed with respect to evolution of the mammalian middle ear. This article is part of the themed issue ‘Evo-devo in the genomics era, and the origins of morphological diversity’.

Dexamethasone Inhibition of the Development of Dysplastic Bony Lesions in Lp/J Mice

1993 ◽  
Vol 102 (10) ◽  
pp. 814-817 ◽  
Author(s):  
Hilary A. Brodie ◽  
Po-Shen Chang ◽  
Richard A. Chole
Keyword(s):  
Middle Ear ◽  
Otic Capsule ◽  
Significant Difference ◽  
Bony Lesions ◽  
And Control ◽  
Relationship Of ◽  
The Relationship

Inbred LP/J mice have been observed to spontaneously develop abnormal bony lesions of the ossicles and otic capsule that progress throughout the life of the animals. This genetically inherited murine disorder produces bony lesions that share some gross and histologic features with bony lesions seen in human tympanosclerosis. Previous studies on LP/J mice have demonstrated evidence of immunologically mediated injury in the progression of the newly forming bony lesions. This study was designed to examine the effects of dexamethasone on the development of the bony lesions in LP/J mice. The purpose was to attempt to elucidate the relationship of the immunologic injury observed in earlier studies and the progression of the dysplastic bony lesions. The results show that LP/J mice treated with dexamethasone developed significantly fewer dysplastic bony lesions compared to the age-matched, saline-treated controls. There was also a statistically significant difference in the quantity and cellularity of the middle ear effusions between the experimental and control animals.

scholarly journals Computed Tomography Image Analysis and Clinical Correlations of Retromaxillary Cells

2020 ◽  
pp. 014556132093696
Author(s):  
Cheng Cao ◽  
Fangwei Zhou ◽  
ZhiYan Song ◽  
Zezhang Tao ◽  
Yu Xu
Keyword(s):  
Computed Tomography ◽  
Paranasal Sinus ◽  
Maxillary Sinusitis ◽  
Anatomical Variation ◽  
Sinus Surgery ◽  
Tomography Image ◽  
Males And Females ◽  
Computed Tomography Image ◽  
Relationship Of ◽  
The Relationship

Objective: This study aimed to investigate and analyze the anatomic characteristics of the retromaxillary cell (RMC) by using computed tomography (CT) images of paranasal sinuses and to improve its identification with ethmomaxillary sinus (EMS). Methods: The paranasal sinus CT scans of 441 outpatients or inpatients in our hospital from January 2018 to October 2018 were analyzed. The incidence of RMC, EMS, Haller cell, imaging anatomical characteristics, and morphological manifestations were observed via sinus CTs. The relationship of RMC and ipsilateral maxillary sinusitis was analyzed. Results: The incidence of RMC is 83.90% (740/882). The incidence of males and females was 83.81% (414/494) and 84.02% (326/388), respectively. The incidence of bilateral (72.79%, 321/441) was much higher than that of unilateral (22.22%, 98/441). The lateral extension of the RMC ranged from 1.18 to 13.31 mm, with an average of 6.10 ± 2.03 mm. The incidence of ipsilateral maxillary sinus opacification on the RMC sides and non-RMC sides has no significance difference (χ2 = .054, P = .459). The incidence of Haller cell and EMS decreased significantly in the presence of RMC ( P < .01). Conclusion: The RMC is an anatomical variation originating from posterior ethmoid cells, which is commonly encountered in the clinic. The pneumatization of RMC is highly variable, and a bilateral is common. During endoscopic sinus surgery, it is necessary to carefully identify such an air cell to ensure the complete opening of the paranasal sinus during surgery.

scholarly journals The Relationship Between Lower Respiratory Tract Microbiome and Allergic Respiratory Tract Diseases in Children

2020 ◽  
Author(s):  
Jinghua Cui ◽  
Yuanyuan Zhang ◽  
Hanqing Zhao ◽  
Zhen Chen ◽  
Quan Zhang ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Absolute Lymphocyte Count ◽  
Allergic Diseases ◽  
Lavage Fluid ◽  
Intestinal Microbiome ◽  
Upper Respiratory Tract ◽  
Healthy Human ◽  
Significant Difference ◽  
The Relationship

Abstract Background: With the development of sequencing technologies, it has been found that there are microbes similar to those in the upper respiratory tract present in the healthy human lower respiratory tract (LRT), including the lungs and bronchus. Thus, to study the LRT microbiome and evaluate the relationship between this microbiome and allergic respiratory diseases in children, we enrolled 68 children who visited the respiratory department and underwent bronchoscopy from January 2018 to December 2018 in the affiliated hospital of the Capital Institute of Pediatrics. Methods: Using the total IgE (TIgE) values, children were divided into two groups: one group had 34 patients with allergy (allergy sensitivity, AS); the second group had 34 patients with no allergy (no allergy sensitivity, NAS). Nucleic acid was extracted from samples of bronchoalveolar lavage fluid (BALF) taken during bronchoscopy treatment and the 16S rDNA gene was sequenced and analysed. Results: The results showed that Haemophilus, Moraxella, Streptococcus, Prevotella, Neisseria, and Rothia were detected in all patients. There was a statistically significant difference in the composition and distribution of microbiota between the AS and NAS groups (p < 0.01). Compared with children in the AS group, the LRT of those belonging to the NAS group were enriched with Streptococcus, Lactobacillus, and Anoxybacillus. However, the level of Bacteroidetes in the AS group was significantly higher. Analysis of the correlation of clinical indices and microbiome showed that TIgE was positively correlated with Bacteroidetes and negatively correlated with Streptococcus. In addition, absolute lymphocyte count showed a relationship with Streptococcus, and the absolute neutrophil count or percentage of neutrophils showed a relationship with Cardiobacterium.Conclusions: The respiratory tract microbiome functioned similarly to the intestinal microbiome. That is, the decrease in microbial diversity and the change in composition could lead to an increase in allergic symptoms. The colonised microbiota of the LRT in children, especially that of Bacteriodetes and Streptococcus, showed a certain correlation with early respiratory allergic diseases. Trial registration number is ISRCTN18302701, and date of registration is 06/10/2020.

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