Increased Lactate Levels Impair the Coagulation System???A Potential Contributing Factor to Progressive Hemorrhage After Traumatic Brain Injury

2006 ◽  
Vol 18 (3) ◽  
pp. 200-204 ◽  
Author(s):  
Martin Engstrom ◽  
Ulf Schott ◽  
Carl-Henrik Nordstrom ◽  
Bertil Romner ◽  
Peter Reinstrup
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Coagulation System ◽  
System A ◽  
Lactate Levels

scholarly journals Hemostasis Disturbances in Patients in the Acute Period of Isolated Traumatic Brain Injury (Review)

2018 ◽  
Vol 14 (5) ◽  
pp. 85-95 ◽  
Author(s):  
A. I. Baranich ◽  
A. A. Sychev ◽  
I. А. Savin ◽  
A. A. Polupan ◽  
A. V. Oshorov ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Protein C ◽  
Coagulation System ◽  
Normal Functioning ◽  
Secondary Brain Damage ◽  
Pathophysiological Mechanisms ◽  
The Brain ◽  
Ischemic Events

Acute isolated traumatic brain injury (TBI) is frequently associated with occurrence of hemostasis disorders, which may be accompanied with hemorrhagic and ischemic events in the brain matter, hence, normal functioning of the blood coagulation system is critical. Understanding of the pathophysiological mechanisms of this phenomenon might help adequate prophylaxis of secondary brain damage. Earlier, development of disseminated intravascular coagulation syndrome (DIC) has been generally considered as a mechanism of coagulation disorders during TBI. However, over the recent decades, new data emerged concerning the key role of tissue factor, systemic inflammation response, thrombocytopathy, protein C effect in the occurrence of this coagulopathy. This overview of literature is aimed at providing the new data on specific pathophysiological mechanisms underlying coagulopathy following TBI.

P.215 Is the IGF system a marker of traumatic brain injury and/or traumatic stress?

2019 ◽  
Vol 29 ◽  
pp. S166
Author(s):  
R. Corne ◽  
M. Ogier ◽  
V. Besson ◽  
S. Ait Si Slimane ◽  
M. Coutan ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Traumatic Stress ◽  
System A ◽  
Igf System

scholarly journals Correlation of arterial blood gas markers and lactate levels with outcomes in pediatric traumatic brain injury

2017 ◽  
Vol 26 (4) ◽  
pp. 246-252 ◽  
Author(s):  
Zhi Min Ng ◽  
Wei Jie Hong ◽  
Shu-Ling Chong ◽  
John C Allen ◽  
Lik Eng Loh ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Blood Gas ◽  
Pediatric Traumatic Brain Injury ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Lactate Levels

scholarly journals A Practical Example Using VR in the Assessment of Brain Injury

1999 ◽  
Vol 4 (1) ◽  
pp. 1-7 ◽  
Author(s):  
R. C. Davies ◽  
G Johansson ◽  
K Boschian ◽  
A. Lindé ◽  
U. Minör ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Assessment Tool ◽  
Occupational Therapists ◽  
Medical Practitioners ◽  
Sound Effects ◽  
System A ◽  
Realistic Interaction ◽  
Computer Based ◽  
Injured Patients

Virtual Reality (VR) as a complementary tool for medical practitioners in the assessment and rehabilitation of people who have suffered a traumatic brain injury (TBI) is discussed. A pilot-study has been undertaken on a prototype VR assessment tool. The design involved nine occupational therapists with expertise in the care of traumatic brain injured patients and one (computer experienced) patient. The aim was to begin a dialogue and to ascertain the potential of a VR system. A common method for occupational therapists to assess function and ability is to ask a patient to brew coffee. From the performance of such a task, an individual's "functional signature" can be determined. The prototype was built using Superscape, a personal computer based VR system, to be close to the real coffee making task, including effects of making mistakes, realistic graphics and sound effects. The world was designed to be as easy to use and intuitive as possible, though problems of mental abstraction level, transfer of training and realistic interaction have yet to be resolved. The comments from the test participants have highlighted problem areas, given positive insight and pointed out other scenarios where VR may be of use in the rehabilitation of people with a traumatic brain injury.

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