scholarly journals 761: BRAIN DEATH MIMICRY AND THE USE OF VA ECMO FOLLOWING POLYSUBSTANCE OVERDOSE: A CASE REPORT

2021 ◽  
Vol 50 (1) ◽  
pp. 374-374
Author(s):  
Christopher Coriasso ◽  
Ahmed Alsaei ◽  
Melinda Miller ◽  
Michael Plisco
Keyword(s):  
2021 ◽  
Vol 16 (1) ◽  
pp. 746-751
Author(s):  
Tao Wang ◽  
Qiancheng Xu ◽  
Xiaogan Jiang

Abstract A 29-year-old woman presented to the emergency department with the acute onset of palpitations, shortness of breath, and haemoptysis. She reported having an abortion (56 days of pregnancy) 1 week before admission because of hyperthyroidism diagnosis during pregnancy. The first diagnoses considered were cardiomyopathy associated with hyperthyroidism, acute left ventricular failure, and hyperthyroidism crisis. The young woman’s cardiocirculatory system collapsed within several hours. Hence, venoarterial extracorporeal membrane oxygenation (VA ECMO) was performed for this patient. Over the next 3 days after ECMO was established, repeat transthoracic echocardiography showed gradual improvements in biventricular function, and later the patient recovered almost completely. The patient’s blood pressure increased to 230/130 mm Hg when the ECMO catheter was removed, and then the diagnosis of phaeochromocytoma was suspected. Computed tomography showed a left suprarenal tumour. The tumour size was 5.8 cm × 5.7 cm with central necrosis. The vanillylmandelic acid concentration was 63.15 mg/24 h. Post-operation, pathology confirmed phaeochromocytoma. To our knowledge, this is the first case report of a patient with cardiogenic shock induced by phaeochromocytoma crisis mimicking hyperthyroidism which was successfully resuscitated by VA ECMO.


2020 ◽  
Author(s):  
Chengfeng Huang ◽  
Shifang Huang ◽  
Jiawen Huang ◽  
Xiaoshen Zhang ◽  
Fanna Liu ◽  
...  

Abstract BackgroundThe brugada syndrome(BrS)is an inherited disorder that can lead to sudden death. A young man who experienced sudden cardiac arrest caused by Brs was successfully rescued after 2hour cardiopulmonary resuscitation (CPR). This is a case that has raised concerns in China (more than 200 million people read this news via the internet).Case presentationA 28 years old young man was successfully managed with Veno-arterial ECMO (VA-ECMO) and continuous renal replacement therapy (CRRT) after more than 2 hours CPR. The diagnosis of BrS was identified during ECMO supported, and further ECG screening found two asymptomatic patients. ConclusionBrS can lead to malignant arrhythmia. VA-ECMO is the rescue treatment for patients with cardiac arrest who cannot be cured by conventional resuscitation. VA-ECMO combined with CRRT may help to improve the prognosis of critically ill patients.


Perinatology ◽  
2016 ◽  
Vol 27 (4) ◽  
pp. 251
Author(s):  
Dong Jun Lee ◽  
Hyun Ah Choi ◽  
Yeon Kyung Lee ◽  
Sun Young Ko ◽  
Son Moon Shin

2009 ◽  
Vol 107 ◽  
pp. S403-S403
Author(s):  
K. Khashia ◽  
G. Rowley ◽  
V. Dickinson ◽  
A. Olubusola ◽  
Z. Anjum

2010 ◽  
Vol 25 (1) ◽  
pp. 53-64 ◽  
Author(s):  
Ari R. Joffe ◽  
Laurance Lequier ◽  
Dominic Cave

2021 ◽  
Author(s):  
Isabella Cristina Mendes Rossa ◽  
Gustavo Lenci Marques ◽  
Carlos Alexandre Twardowschy

Abstract Female patient, 44 years old, admitted with symptoms of COVID-19. She presented elevation of cardiac troponin I, as well as diffuse hypokinesia in transthoracic echocardiography, which suggested the diagnosis of myocarditis. Next, a skull tomography showed diffuse cerebral edema and tonsilar herniation, and the patient evolved with brain death


2019 ◽  
Vol 131 (6) ◽  
pp. 1773-1779 ◽  
Author(s):  
Andrew P. Carlson ◽  
C. William Shuttleworth ◽  
Sebastian Major ◽  
Coline L. Lemale ◽  
Jens P. Dreier ◽  
...  

The authors report on a 57-year-old woman in whom progression to brain death occurred on day 9 after aneurysmal subarachnoid hemorrhage without evidence of significant brain edema or vasospasm. Neuromonitoring demonstrated that brain death was preceded by a series of cortical spreading depolarizations that occurred in association with progressive hypoxic episodes. The depolarizations induced final electrical silence in the cortex and ended with a terminal depolarization that persisted > 7 hours. To the authors’ knowledge, this is the first report of terminal spreading depolarization in the human brain prior to clinical brain death and major cardiopulmonary failure.


2021 ◽  
pp. 1-9
Author(s):  
Priciane Bárbara Ewerling Penna ◽  
◽  
Maria Cândida Moreno Penna ◽  
Douglas Domingues ◽  
Fernando Ferreira Penna Filho ◽  
...  

Introduction: The current COVID-19 pandemic has involved developing vaccines to control the virulence of SARS-CoV-2. More than 4.1 million people have died from COVID-19.1 In response to this public health emergency, several vaccines against COVID-19 have been developed, with more than 3.7 billion doses administered worldwide. After the introduction of the adenovirus vector vaccine ChAdOx1, several cases of severe venous thrombosis with thrombocytopenia were reported worldwide. Objective: It was to present a case report of a 25-year-old female patient who presented extensive left intraparenchymal hematoma and rapid progression to brain death followed by death. Case report: A 25-year-old woman, CSS, was vaccinated against COVID-19 with the adenovirus ChAdOx1, 14 days after admission, evolved with a fever that started about 13 days ago, associated with holocranial, tight, moderate-intensity headache. On the day of admission, she was found by the torporous, unresponsive, and vomiting family, referred to the hospital emergency room. The patient was admitted to Glasgow 4 with evidence of anisocoria, with the left pupils larger than the right, rapidly progressing to mydriasis. Cranial computed tomography (CT) showed extensive left intraparenchymal hematoma, performing urgent decompressive craniectomy and placement of an intracranial pressure monitoring catheter. The cerebrospinal fluid exam did not show bacteria or fungi. CT angiography showed extensive thrombosis of the anterior portions of the superior sagittal sinus and probable thrombosis of the superficial drainage veins of the frontal regions. Skull CT revealed diffuse and bilateral ischemia. Laboratory tests showed mild thrombocytopenia and no change in the coagulogram. After one day, the patient evolved with worsening neurological status. Sedation was turned off to start the brain death protocol, which was confirmed twice. Finally, an electroencephalogram was performed with evidence of a straight-line tracing, without evidence of electrical brain activity. Final considerations: Several studies have been published regarding cerebral thrombosis, stroke, and thrombotic thrombocytopenic events. Thus, safe and effective vaccines against COVID-19 are an urgent need, as they can leave pathophysiological responses of hypercoagulability and thrombo inflammation associated with acute infection.


2021 ◽  
Author(s):  
Isabella Cristina Mendes Rossa ◽  
Gustavo Lenci Marques ◽  
Carlos Alexandre Twardowschy

Abstract Female patient, 44 years old, admitted with symptoms of COVID-19. She presented elevation of cardiac troponin I, as well as diffuse hypokinesia in transthoracic echocardiography, which suggested the diagnosis of myocarditis. Next, a skull tomography showed diffuse cerebral edema and tonsilar herniation, and the patient evolved with brain death


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