MPS 18-03 VITAMIN C PREVENTS DECREASE OF BLEEDING TIME; AN EXPERIMENTAL STUDY USING MICE INDUCED CIGARETTE SMOKE

2016 ◽  
Vol 34 (Supplement 1) ◽  
pp. e423
Author(s):  
Alles Firmansyah ◽  
Zelly Dia Rofinda ◽  
Erkadius Erkadius
Keyword(s):  
Experimental Study ◽  
Vitamin C ◽  
Cigarette Smoke ◽  
Bleeding Time

The Potential Effect of Mucuna pruriens Seed Extract on Sperm Quality experimental study on mice exposed to cigarette smoke

2021 ◽  
Vol 20 (4) ◽  
pp. 768-773
Author(s):  
Meidona Nurul Milla ◽  
Yani Istadi ◽  
Vania Shaula ◽  
Deastri Anjeas Wari ◽  
Chntyia Dwi Cahyani Puspitasari ◽  
...  
Keyword(s):  
Experimental Study ◽  
Cigarette Smoke ◽  
Sperm Quality ◽  
Medical Science ◽  
Seed Extract ◽  
Reproductive Age ◽  
Testicular Atrophy ◽  
Mucuna Pruriens ◽  
Control Group

Background: Infertility has been more common problems among couple of reproductive age. One of the factors causing this disorder is unhealthy environmental factors including exposure to cigarette smoke. Polynuclear aromatic hydrocarbons (PAHs) in cigarette smoke can cause testicular atrophy, while the free radicals can inhibit the stages of spermatogenesis, and nicotine in cigarettes affects the brain dopamine levels affecting the levels of GnRH, and subsequently affect the levels of FSH and LH needed in spermatogenesis. The use of Mucuna pruriens seed extract containing antioxidants and L-dopa is expected to improve the quality of sperm after exposure to cigarette smoke. Objective: This study aimed to determine the effect of Mucuna pruriens seed extract on the sperm quality in mice exposed to cigarette smoke. Methods: This study was an experimental study with a post test only control group design. A total of 20 mice were divided into 4 groups of five mice each. All groups were exposed to cigarette smoke. Group 1 was the negative control exposed to cigarette smoke. Groups 2, 3, 4 were exposed to cigarettes smoke and given Mucuna pruriens seed extracts at the dose of 250; 300; and 350 mg/Kg BW/day. Parameters of sperm quality included concentration, morphology, motility and viability. Results: Post hoc tests showed there were significant differences among treatment groups. Conclusion: the administration of Mucuna pruriens seed extract affects the sperm quality of BALB/c mice exposed to cigarettes smoke. Bangladesh Journal of Medical Science Vol.20(4) 2021 p.768-773

scholarly journals Oral Leukoplakia and Costochondral Hyperplasia Induced by Diethylnitrosamine in Hamsters Exposed to Cigarette Smoke with or without Dietary Vitamin C

1987 ◽  
Vol 24 (3) ◽  
pp. 257-264 ◽  
Author(s):  
T. Harada ◽  
A. Enomoto ◽  
T. Kitazawa ◽  
K. Maita ◽  
Y. Shirasu
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Vitamin C ◽  
Cigarette Smoke ◽  
Precancerous Lesions ◽  
Costal Cartilage ◽  
Oral Leukoplakia ◽  
Smoke Inhalation ◽  
Dietary Vitamin ◽  
Scanning Electron

Male Syrian golden hamsters receiving 12 weekly subcutaneous injections of diethylnitrosamine (DEN) were subjected to cigarette smoke inhalation and fed a diet with or without 1% vitamin C supplement for a period of 58 weeks. Another group was a sham-smoked control and was not fed vitamin C. Tissues of the oral cavity and costal cartilage were examined by light and/or scanning electron microscopy. Oral leukoplakia and costochondral hyperplasia occurred with high frequency in all groups treated with DEN. Leukoplakic lesions were found in the palate, tongue, and pharynx; the early change was focal erosion with mild epithelial hyperplasia and inflammatory cell infiltration. Advanced lesions had marked mucosal thickening due to acanthosis, parakeratosis, hyperkeratosis, and submucosal infiltration of lymphocytes and plasma cells. Precancerous lesions were noted in tongue and pharynx. Scanning electron microscopy of tongues revealed destruction of filiform papillae. The incidence of leukoplakic lesions was higher in smoke-exposed hamsters than in controls, but the incidence in vitamin C-supplemented hamsters was low when compared with the smoke-exposed hamsters without vitamin C. Costochondral hyperplasia was initiated by thickening of the perichondrium followed by proliferation of chondrocytes. Costochondral hyperplasia appeared earlier, and the incidence was higher in the vitamin C-supplemented hamsters. It could not be determined whether costochondral hyperplasia was the primary lesion induced by DEN or secondary change.

Experimental Study on Effect of Cigarette Smoke Condensate on Bronchial Mucosa

JAMA ◽  
1962 ◽  
Vol 182 (11) ◽  
Author(s):  
E. E. Rockey ◽  
F. D. Speer ◽  
S. A. Thompson ◽  
K. J. Ahn ◽  
T. Hirose
Keyword(s):  
Experimental Study ◽  
Cigarette Smoke ◽  
Bronchial Mucosa ◽  
Cigarette Smoke Condensate

scholarly journals Studi Pembuatan Biskuit Fungsional dengan Substitusi Tepung Ikan Gabus dan Tepung Daun Kelor

2018 ◽  
Vol 1 (2) ◽  
pp. 155-162
Author(s):  
Rina Sugiarti Dwi Gita ◽  
Sarwo Danuji
Keyword(s):  
Experimental Study ◽  
Vitamin A ◽  
Vitamin C ◽  
Water Content ◽  
Fat Content ◽  
Test Method ◽  
Organoleptic Test

The objective of the study was to find out the content of macro and micro nutrient in kelor leaves biscuits flour and snakehead fish. The study was an experimental study which was conducted at the laboratory. The instruments used were blender, filter, oven, chopping block, knife, basin, panic, gloves, stove, baking pan, flat basket, mixer, small plate, weighing scale, and triangle plastic. The result of the study indicated that out of 6 formula from the product which has the highest value, such as based on organoleptic test, with hedonic test method, was formula B5. Then the macro and micro nutrient of the formula was analyzed. The result of the analysis showed the water content was 5,04 % in the biscuits. The ashes content was 1,60%. The fat content was 31,67%. The protein was 19,24%. The carbohydrate was 42,74%. The analysis result on the micro nutrient showed the. Magnesium was 12,69%, Calsium 96,06 %, Zn 0,04%, Vitamin C 69,99%, Vitamin A 259,4%, Fosfor 19,92%. In conclusion, kelor leaves biscuits flour and snakehead fish, which was produced, contain some nutrients which meet the SNI requirements of biscuits production. Keywords: kelor leaves , snakehead fish, biscuits

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