Nested Case???Control Study of Cervical Mucosal Lesions, Ectopy, and Incident HIV Infection Among Women in Cape Town, South Africa

2006 ◽  
Vol 33 (11) ◽  
pp. 683-687 ◽  
Author(s):  
Landon Myer ◽  
Thomas C. Wright ◽  
Lynette Denny ◽  
Louise Kuhn
2006 ◽  
Vol 193 (3) ◽  
pp. 458-466 ◽  
Author(s):  
James Todd ◽  
Heiner Grosskurth ◽  
John Changalucha ◽  
Angela Obasi ◽  
Frank Mosha ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Mu-Lin Chiu ◽  
Wen-Miin Liang ◽  
Ju-Pi Li ◽  
Chi-Fung Cheng ◽  
Jian-Shiun Chiou ◽  
...  

The progression of acquired immunodeficiency syndrome is delayed in patients with human immunodeficiency virus (HIV) infection receiving antiretroviral therapy (ART). However, long-term ART is associated with adverse effects. Osteoporosis is one of the adverse effects and is a multifactorial systemic skeletal disease associated with bone fragility and an increased risk of fracture. We performed a longitudinal, comprehensive, nested case-control study to explore the effect of ART on the risk of osteoporosis in 104 osteoporotic and 416 non-osteoporotic patients with HIV infection at their average age about 29 years old in Taiwan. Patients with history of ART, current exposure to ART, higher cumulative defined daily doses (DDDs), or higher ART adherence were at a higher risk of osteoporosis (p < 0.05). Patients receiving nucleoside/nucleotide reverse transcriptase inhibitor (NRTI)-containing regimen (zidovudine-lamivudine combination, lamivudine-abacavir combination, and abacavir alone) and protease inhibitor (PI)-containing regimen (lopinavir-ritonavir combination, ritonavir, and atazanavir) had a higher risk of osteoporosis (p < 0.05). Especially, patients receiving high doses of the PIs lopinavir-ritonavir combination had an increased risk of osteoporosis (p < 0.05). In conclusion, history of ART, current exposure to ART, higher cumulative DDDs, and higher ART adherence were associated with an increased risk of osteoporosis. Furthermore, NRTI- and PI-containing regimens and high doses of PIs lopinavir-ritonavir combination may be associated with an increased risk of osteoporosis in patients with HIV infection in Taiwan.


Seizure ◽  
2019 ◽  
Vol 65 ◽  
pp. 159-165 ◽  
Author(s):  
R.J. Burman ◽  
J.M. Wilmshurst ◽  
S. Gebauer ◽  
L. Weise ◽  
K.G. Walker ◽  
...  

2005 ◽  
Vol 192 (8) ◽  
pp. 1372-1380 ◽  
Author(s):  
Landon Myer ◽  
Lynette Denny ◽  
Robin Telerant ◽  
Michelle de Souza ◽  
Thomas C. Wright, Jr. ◽  
...  

AIDS Care ◽  
2015 ◽  
Vol 27 (3) ◽  
pp. 342-349 ◽  
Author(s):  
Sarah Dewing ◽  
Cathy Mathews ◽  
Mark Lurie ◽  
Ashraf Kagee ◽  
Trishanta Padayachee ◽  
...  

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