Procalcitonin as a Marker of Severe Bacterial Infection in Children in the Emergency Department

2010 ◽  
Vol 26 (1) ◽  
pp. 61-63
Author(s):  
&NA;
Keyword(s):  
Emergency Department ◽  
Bacterial Infection ◽  
Severe Bacterial Infection

scholarly journals Severe bacterial infection in young infants with pyrexia admitted to the emergency department

Medicine ◽  
2021 ◽  
Vol 100 (27) ◽  
pp. e26596
Author(s):  
Yin-Ting Chen ◽  
Yu-Jun Chang ◽  
Bang-Yan Liu ◽  
En-Pei Lee ◽  
Han-Ping Wu
Keyword(s):  
Emergency Department ◽  
Bacterial Infection ◽  
Severe Bacterial Infection ◽  
Young Infants

Procalcitonin as a Marker of Severe Bacterial Infection in Children in the Emergency Department

2010 ◽  
Vol 26 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Jamie N. Deis ◽  
Clarence B. Creech ◽  
Cristina M. Estrada ◽  
Thomas J. Abramo
Keyword(s):  
Emergency Department ◽  
Bacterial Infection ◽  
Severe Bacterial Infection

scholarly journals Risk factors for death in suspected severe bacterial infection in infants aged <90 days in Luanda, Angola

2021 ◽  
Vol 106 ◽  
pp. 223-227
Author(s):  
Tuula Pelkonen ◽  
Suvi Urtti ◽  
Ondina Cardoso ◽  
Moe H. Kyaw ◽  
Irmeli Roine ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bacterial Infection ◽  
Severe Bacterial Infection

Comparison of peripheral and central capillary refill time in febrile children presenting to a paediatric emergency department and its utility in identifying children with serious bacterial infection

2016 ◽  
Vol 102 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Evelien de Vos-Kerkhof ◽  
Tarik Krecinic ◽  
Yvonne Vergouwe ◽  
Henriëtte A Moll ◽  
Ruud G Nijman ◽  
...  
Keyword(s):  
Emergency Department ◽  
Body Temperature ◽  
General Population ◽  
Bacterial Infection ◽  
Capillary Refill Time ◽  
Radiographic Findings ◽  
Capillary Refill ◽  
Clinical Criteria ◽  
Paediatric Emergency Department ◽  
Paediatric Emergency

ObjectiveTo determine the agreement between peripheral and central capillary refill time (pCRT/cCRT) and their diagnostic values for detecting serious bacterial infection (SBI) in febrile children attending the paediatric emergency department (ED).DesignProspective observational study.SettingPaediatric ED, Erasmus Medium Care-Sophia Children's hospital, the Netherlands.Patients1193 consecutively included, previously healthy, febrile children (1 month–16 years) with both pCRT measurements and cCRT measurements available. SBI diagnosis was based on abnormal radiographic findings and/or positive cultures from normally sterile locations in addition to clinical criteria.Main outcome measuresAgreement between pCRT and cCRT (Cohen's κ), overall and stratified for age and body temperature. The diagnostic value of pCRT and cCRT for SBI was assessed with logistic regression.ResultsOverall agreement was 0.35 (95% CI 0.27 to 0.43; considered ‘fair’). Although not significant, agreement was lower in children aged 1–<5 years (κ: 0.15 (95% CI 0.04 to 0.27)) and decreased with higher body temperatures with κ ranging from 0.55 (95% CI 0.32 to 0.79) for temperature <37.5°C to 0.21 (95% CI 0.07 to 0.34) for temperature >39.5°C. Abnormal pCRT (>2 s) was observed in 153 (12.8%; 95% CI 10.9% to 14.7%) and abnormal cCRT in 55 (4.6%; 95% CI 3.4% to 5.8%) children. The OR of abnormal pCRT (>2 s) for predicting SBI was 1.10 (95% CI 0.65 to 1.84). For abnormal cCRT (>2 s), the OR was 0.43 (95% CI 0.13 to 1.39).ConclusionsThe pCRT and cCRT values showed only fair agreement in a general population of febrile children at the ED, and no significant association with age or body temperature was found. Only a small part of febrile children at risk for serious infections at the ED show abnormal CRT values. Both abnormal pCRT and cCRT (defined as >2 s) performed poorly and were non-significant in this study detecting SBI in a general population of febrile children.

Likelihood of Bacterial Infection in Patients Treated With Broad-Spectrum IV Antibiotics in the Emergency Department

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Claire N. Shappell ◽  
Michael Klompas ◽  
Aileen Ochoa ◽  
Chanu Rhee
Keyword(s):  
Emergency Department ◽  
Bacterial Infection ◽  
Broad Spectrum

Trends in ED Resource Use for Infants 0 to 60 Days Evaluated for Serious Bacterial Infection

2021 ◽  
Author(s):  
Christina S. Hernandez ◽  
Michael C. Monuteaux ◽  
Richard G. Bachur ◽  
Jeanine E. Hall ◽  
Pradip P. Chaudhari
Keyword(s):  
Emergency Department ◽  
Bacterial Infection ◽  
Resource Use ◽  
Temporal Trends ◽  
Health Information System ◽  
Cross Sectional Study ◽  
Antibiotic Administration ◽  
Hospital Level ◽  
Cross Sectional ◽  
Department Evaluation

OBJECTIVES We examined trends in resource use for infants undergoing emergency department evaluation for serious bacterial infection, including lumbar puncture (LP), antibiotic administration, hospitalization, and procalcitonin testing, as well as the association between procalcitonin testing and LP, administration of parenteral antibiotics, and hospitalization. METHODS We performed a cross-sectional study of infants aged 0 to 60 days who underwent emergency department evaluation for serious bacterial infection with blood and urine cultures from 2010 to 2019 in 27 hospitals in the Pediatric Health Information System. We examined temporal trends in LP, antibiotic administration, hospitalization, and procalcitonin testing from 2010 to 2019. We also estimated multivariable logistic regression models for 2017–2019, adjusted for demographic factors and stratified by age (&lt;28 and 29–60 days), with LP, antibiotic administration, and hospitalization as dependent variables and hospital-level procalcitonin testing as the independent variable. RESULTS We studied 106 547 index visits. From 2010 to 2019, rates of LP, antibiotic administration, and hospitalization decreased more for infants aged 29 to 60 days compared with infants aged 0 to 28 days (annual decrease in odds of LP, antibiotics administration, and hospitalization: 0 to 28 days: 5%, 5%, and 3%, respectively; 29–60 days: 15%, 12%, and 7%, respectively). Procalcitonin testing increased significantly each calendar year (odds ratio per calendar year 2.19; 95% confidence interval 1.82–2.62), with the majority (91.1%) performed during 2017–2019. From 2017 to 2019, there was no association between hospital-level procalcitonin testing and any outcome studied (all P values &gt; .05). CONCLUSIONS Rates of LP, antibiotic administration, and hospitalization decreased significantly for infants 29 to 60 days during 2010–2019. Although procalcitonin testing increased during 2017–2019, we found no association with hospital-level procalcitonin testing and patterns of resource use.

scholarly journals Prevalence of Sepsis and Possible Severe Bacterial Infection among Neonates in Nepal

2018 ◽  
Vol 16 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Gambhir Shrestha ◽  
Rashmi Mulmi ◽  
Nibaran Joshi ◽  
Parashu Ram Shrestha
Keyword(s):  
Systematic Review ◽  
Bacterial Infection ◽  
Neonatal Sepsis ◽  
Signs And Symptoms ◽  
Nationwide Survey ◽  
Community Based ◽  
Eligibility Criteria ◽  
Severe Bacterial Infection ◽  
Review Criteria ◽  
Adequate Data

Nepal lacks adequate data on the prevalence of sepsis and Possible Severe Bacterial Infection (PSBI) among neonates. Thus, this systematic review was designed to estimate the prevalence of neonatal sepsis and PSBI status in Nepal. We searched PubMed and Nepal Journal Online for relevant studies on PSBI and neonatal sepsis published from 2006 to 2016. The eligibility criteria included those studies done in Nepal, evaluating the prevalence of PSBI/neonatal sepsis with denominators as the population at risk that is either total live births or total cases evaluated. Altogether, four studies met the review criteria, out of which three were hospital-based and one community-based. There is a vast difference in prevalence rate between hospital-based (2-4%) and community-based (9%) studies. Two studies used haematological scoring system and blood culture to base their diagnosis; one used signs and symptoms for PSBI while the other did not mention the diagnostic criteria. This systematic review suggests that though neonatal sepsis poses a big problem, it lacks a significant number of related studies. There is a need to conduct a nationwide survey on the prevalence of sepsis and PSBI among neonates, which will help to develop health policy.

Sign in / Sign up

Export Citation Format

Share Document