IMPROVEMENT IN VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH CENTRAL SEROUS CHORIORETINOPATHY AFTER MACULAR SUBTHRESHOLD LASER THERAPY

Purpose: The purpose of this study was to evaluate the role of 532 nm transfoveal subthreshold micropulse laser in non-resolving central serous chorioretinopathy with subfoveal leak. Methods: A retrospective chart analysis of 23 eyes of 21 patients with central serous chorioretinopathy was performed. Inclusion criteria include vision loss ⩾3 months and focal subfoveal leak on fluorescein angiography. Exclusion criteria include prior treatment for central serous chorioretinopathy and chronic central serous chorioretinopathy. All eyes were treated with 532 nm subthreshold micropulse laser (5% duty cycle). Visual acuity score, contrast sensitivity, autofluorescence, spectral domain optical coherence tomography, and fundus fluorescein angiography were assessed at baseline, 1, 3, 6 months. Results: Average visual acuity score (letters) improved from 66.0 ± 8.51 (baseline) to 71.35 ± 8.48 (1 month, p < 0.01), 77.30 ± 11.34 (3 months, p < 0.01), 80.17 ± 9.30 (6 months, p < 0.01). Contrast sensitivity improved from 0.75 ± 0.30 to 1.30 ± 0.37 ( p < 0.01) at 6 months. Two eyes needed rescue laser at 3 months followed by photodynamic therapy at 6 months; two eyes needed rescue laser at 6 months. Conclusion: The 532 nm subthreshold micropulse laser is safe in non-resolving central serous chorioretinopathy with subfoveal leaks.

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Pattern of Contrast Sensitivity Changes in Acute Central Serous Chorioretinopathy

Journal of Ophthalmology ◽

10.1155/2017/9053932 ◽

2017 ◽

Vol 2017 ◽

pp. 1-8 ◽

Cited By ~ 3

Author(s):

Preeyachan Lourthai ◽

Patama Bhurayanontachai

Keyword(s):

Visual Acuity ◽

Photodynamic Therapy ◽

Contrast Sensitivity ◽

Central Serous Chorioretinopathy ◽

Subretinal Fluid ◽

Spontaneous Resolution ◽

Fellow Eye ◽

Spatial Frequencies ◽

Acute Central Serous Chorioretinopathy ◽

Sensitivity Changes

Purpose. To evaluate contrast sensitivity (CS) changes in acute central serous chorioretinopathy (CSC). Methods. Visual acuity (VA), CS, and subretinal fluid (SRF) were evaluated monthly for 6 months. Treatment was considered at 3 months in case of persistent SRF. Results. Twelve of 20 eyes (60%) had spontaneous SRF resolution within 4 months. Five of 8 patients with delayed SRF resolution received either focal laser or photodynamic therapy. The CS was impaired in all spatial frequencies at baseline. There was a negative correlation between the baseline SRF thickness and CS at 3 and 6 cycles per degree (cpd). The CS improved significantly at the time of fluid resolution (p=0.001) and continued to improve in 3 and 6 cpd. The CS at 6 cpd did not recover if compared to a normal fellow eye at 6 months (p=0.018). The CS of 12 cpd at 6 months was superior in the spontaneous resolution group. Conclusion. The impaired CS gradually improved as the SRF reduced at all spatial frequencies. CS at 3 and 12 cpd continued to improve after complete fluid resolution. Despite an excellent final VA, the CS at 6 months did not regain its normal value.

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Effect of incompatible light on modified class B night vision goggle-aided visual acuity and contrast sensitivity.

PsycEXTRA Dataset ◽

10.1037/e422132004-001 ◽

1997 ◽

Author(s):

Randall W. Gibb ◽

Jack D. Reising

Keyword(s):

Visual Acuity ◽

Contrast Sensitivity ◽

Night Vision ◽

Class B

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Pediatric Cataract Surgery: Comparison between Ages at Surgery and Contrast Sensitivity Outcomes

Ophthalmologica Indonesiana ◽

10.35749/journal.v43i1.138 ◽

2019 ◽

Vol 43 (1) ◽

pp. 50

Author(s):

Aquirina Caesari Putri ◽

Rozalina Loebis

Keyword(s):

Visual Acuity ◽

Cataract Surgery ◽

Contrast Sensitivity ◽

Cataract Extraction ◽

Significant Negative Correlation ◽

Natural World ◽

P Value ◽

Pediatric Cataract ◽

Low Contrast ◽

Significant Difference

Background: Pediatric cataracts are major causes of children’s blindness. Surgery has proven to be beneficial in terms of visual function prognosis. Contrast sensitivity evaluation after surgery is as important as visual acuity considering that natural world consists of various objects in low-to-medium contrasts. The purpose of this study is to analyze the difference of contrast sensitivity outcomes based on ages at surgery. Method: Retrospective data of children with pediatric developmental cataract from July 2013 to November 2015 were collected. All children who underwent cataract surgery at 60-months-old or less were randomized into two groups, ≤24 months and >24-to-60 months. Contrast sensitivity was then examined with preferential-looking method using Hiding Heidi low-contrast test face chart. The main outcome measures were contrast sensitivity of both groups. Age-at-evaluation, cataract onset, duration of follow-up, duration of deprivation and visual acuity were also noted. Result: Of 14 children (23 eyes), 11 eyes (47,8%) were in ≤24 months group, 12eyes (52,2%) were in >24-to-60 months group. All eyes underwent cataract extraction and similar type of intraocular lens implantation. Mean age-at-surgery was 28,2 months±16,8 (SD). Mean contrast sensitivity for each group was 47,50 %±42,29 and 18,33%±27,38, respectively, with p-value 0,031. Further analysis of Spearman’s correlation test demonstrated significant negative correlation (rs = -0,559; p = 0,006) between the two groups. Conclusion: There was statistically significant difference in contrast sensitivity between those who underwent surgery at ≤24 months and >24-to-60 months. Children who underwent surgery at older ages tend to have better contrast sensitivity afterwards.

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Comparison of Retinal Layer Thickness and Capillary Vessel Density in the Patients with Spontaneously Resolved Acute Central Serous Chorioretinopathy

Journal of Clinical Medicine ◽

10.3390/jcm10010045 ◽

2020 ◽

Vol 10 (1) ◽

pp. 45

Author(s):

Kyu Jin Han ◽

Hyeong Ju Kim ◽

Je Moon Woo ◽

Jung Kee Min

Keyword(s):

Visual Acuity ◽

Layer Thickness ◽

Central Serous Chorioretinopathy ◽

Subretinal Fluid ◽

Vessel Density ◽

Foveal Avascular Zone ◽

Retinal Layer ◽

Healthy Controls ◽

Retrospective Case ◽

Capillary Vessel

We investigate retinal layer thickness and capillary vessel density (VD) in the patients with central serous chorioretinopathy (CSC) who recovered spontaneously and evaluate the correlation between the changes in these values and visual outcomes using swept-source optical coherence tomography (SS-OCT) and OCT angiography (OCTA). This retrospective case–control study included 34 eyes of 34 patients with spontaneously resolved acute CSC. The changes in retinal layer thickness and capillary VD were examined using SS-OCT and OCTA after complete resolution of subretinal fluid (SRF). The fellow eyes and 34 healthy eyes were used as controls. In the eyes with CSC, the outer retinal layer was significantly thinner than in the eyes of fellow and healthy controls. The foveal avascular zone area and VDs in the superficial and deep capillary plexus in the eyes with CSC were not significantly different from those in the eyes of fellow and healthy controls. The VD of the choriocapillaris in the eyes with CSC was significantly lower than that in the eyes of fellow and healthy controls. Correlation analyses revealed that the outer retinal layer thickness and initial visual acuity were positively correlated with the final visual acuity. Furthermore, the initial SRF area and height were negatively correlated with the outer retinal layer thickness after SRF resolution. Attenuation of outer retinal layer thickness and decreased VD of the choriocapillaris were observed in the eyes with spontaneously resolved acute CSC. The outer retinal layer thickness could be an important visual predictor of CSC.

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Improved CoChR Variants Restore Visual Acuity and Contrast Sensitivity in a Mouse Model of Blindness under Ambient Light Conditions

Molecular Therapy ◽

10.1016/j.ymthe.2019.04.002 ◽

2019 ◽

Vol 27 (6) ◽

pp. 1195-1205 ◽

Cited By ~ 14

Author(s):

Tushar H. Ganjawala ◽

Qi Lu ◽

Mitchell D. Fenner ◽

Gary W. Abrams ◽

Zhuo-Hua Pan

Keyword(s):

Visual Acuity ◽

Mouse Model ◽

Contrast Sensitivity ◽

Ambient Light ◽

Light Conditions

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The impact of cataract surgery on depressive symptoms for bilateral cataract patients in Ho Chi Minh City, Vietnam

International Psychogeriatrics ◽

10.1017/s1041610213001907 ◽

2013 ◽

Vol 26 (2) ◽

pp. 307-313 ◽

Cited By ~ 6

Author(s):

Kien Gia To ◽

Lynn B. Meuleners ◽

Michelle L. Fraser ◽

Dat Van Duong ◽

Dung Van Do ◽

...

Keyword(s):

Visual Acuity ◽

Depressive Symptoms ◽

Cataract Surgery ◽

Contrast Sensitivity ◽

Depression Scale ◽

Epidemiological Studies ◽

Ho Chi Minh City ◽

Bilateral Cataract ◽

Vietnamese Population ◽

The Impact

ABSTRACTBackground:Depression is common among older populations with cataract. However, the impact of cataract surgery on depression in both developed and developing countries remains unclear. The aim of this study is to determine the impact of cataract surgery on depressive symptoms and to examine the association between objective visual measures and change in depressive symptoms after surgery among a Vietnamese population in Ho Chi Minh City.Methods:A cohort of older patients with bilateral cataract were assessed the week before and one to three months after first eye surgery only or first- and second-eye cataract surgeries. Visual measures including visual acuity, contrast sensitivity, and stereopsis were obtained. Depressive symptoms were assessed using the 20-item Center for Epidemiological Studies-Depression Scale (CES-D). Descriptive analyses and a generalized estimating equations (GEE) analysis were undertaken to determine the impact of cataract surgery on depressive symptoms.Results:Four hundred and thirteen participants were recruited into the study before cataract surgery. Two hundred and forty-seven completed the follow-up assessment after surgery. There was a significant decrease (improvement) of one point in the depressive symptoms score (p = 0.04) after cataract surgery, after accounting for potential confounding factors. In addition, females reported a significantly greater decrease (improvement) of two points in depressive symptom scores (p = 0.01), compared to males. However, contrast sensitivity, visual acuity, and stereopsis were not significantly associated with change in depressive symptoms scores. First-eye cataract surgery or both-eye cataract surgery did not modify the change in depressive symptoms score.Conclusion:There was a small but significant improvement in depressive symptoms score after cataract surgery for an older population in Vietnam.

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