Nutrition-associated processes govern fungal pathogenicity

There is evidence that secondary metabolites are involved in the fungal pathogenicity and virulence of Neofusicoccum spp. Fatty acids may also influence the plant–pathogen interaction but, so far, no information is available on their production by species of Neofusicoccum associated with Botryosphaeria dieback, which is a well-known syndrome of several plants with a complex etiology. In the present paper, the production of fatty acids in liquid medium, by strains of N. vitifusiforme and N. parvum associated with declining Sicilian vine plants, was evaluated. Data, acquired via gas chromatography–mass spectrometry (GC/MS), show the presence of linoleic acid as the most abundant fatty acid produced by both examined strains. In addition, the pathogenicity of N. vitifusiforme was tested on 2-year-old grapevine plants of cv. Inzolia.

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Sporothrix schenckii complex biology: environment and fungal pathogenicity

Microbiology ◽

10.1099/mic.0.081794-0 ◽

2014 ◽

Vol 160 (11) ◽

pp. 2352-2365 ◽

Cited By ~ 37

Author(s):

M. D. Téllez ◽

A. Batista-Duharte ◽

D. Portuondo ◽

C. Quinello ◽

R. Bonne-Hernández ◽

...

Keyword(s):

Environmental Factors ◽

Subcutaneous Tissue ◽

Sporothrix Schenckii ◽

Aetiological Agent ◽

Natural Habitats ◽

Fungal Pathogenicity ◽

Adverse Conditions ◽

Outdoor Environments ◽

Animal Hosts ◽

Medical Importance

Sporothrix schenckii is a complex of various species of fungus found in soils, plants, decaying vegetables and other outdoor environments. It is the aetiological agent of sporotrichosis in humans and several animals. Humans and animals can acquire the disease through traumatic inoculation of the fungus into subcutaneous tissue. Despite the importance of sporotrichosis, it being currently regarded as an emergent disease in several countries, the factors driving its increasing medical importance are still largely unknown. There have only been a few studies addressing the influence of the environment on the virulence of these pathogens. However, recent studies have demonstrated that adverse conditions in its natural habitats can trigger the expression of different virulence factors that confer survival advantages both in animal hosts and in the environment. In this review, we provide updates on the important advances in the understanding of the biology of Spor. schenckii and the modification of its virulence linked to demonstrated or putative environmental factors.

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Molecular Bases of Fungal Pathogenicity to Plants

Gene Manipulations in Fungi ◽

10.1016/b978-0-12-088640-1.50023-9 ◽

1985 ◽

pp. 417-448 ◽

Cited By ~ 6

Author(s):

O.C. YODER ◽

B. GILLIAN TURGEON

Keyword(s):

Fungal Pathogenicity ◽

Molecular Bases

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Fungal Pathogenicity and the Plant's Response

10.1016/b978-0-121-48850-5.x5001-9 ◽

1973 ◽

Keyword(s):

Fungal Pathogenicity

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Limitations of transcriptome-based prediction of pathogenicity genes in the plant pathogen Leptosphaeria maculans

FEMS Microbiology Letters ◽

10.1093/femsle/fnz080 ◽

2019 ◽

Vol 366 (7) ◽

Cited By ~ 2

Author(s):

Andrew S Urquhart ◽

Alexander Idnurm

Keyword(s):

Gene Expression ◽

Brassica Napus ◽

Leptosphaeria Maculans ◽

Simple Expression ◽

Gene Transcript ◽

Blackleg Disease ◽

Fungal Pathogenicity ◽

Transcript Levels ◽

Oilseed Crops ◽

High Gene

ABSTRACT Identification of pathogenicity determinants in Leptosphaeria maculans, a major cause of disease of oilseed crops, has been a focus of research for many years. A wealth of gene expression information from RNA sequencing promises to illuminate the mechanisms by which the fungus is able to cause blackleg disease. However, to date, no studies have tested the hypothesis that high gene transcript levels during infection correlate with importance to disease progression. In this study, we use CRISPR-Cas9 to disrupt 11 genes that are highly expressed during the early stages of disease and show that none of these genes are crucial for fungal pathogenicity on Brassica napus. This finding suggests that in order to understand the pathogenicity of this fungus more sophisticated techniques than simple expression analysis will need to be employed.

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