Hepatitis B Virus Exposure During Childhood in Cameroon, Central African Republic and Senegal After the Integration of HBV Vaccine in the Expanded Program on Immunization

2013 ◽  
Vol 32 (10) ◽  
pp. 1110-1115 ◽  
Author(s):  
Marie-Anne Rey-Cuille ◽  
Richard Njouom ◽  
Claudine Bekondi ◽  
Abdoulaye Seck ◽  
Chrysostome Gody ◽  
...  
PEDIATRICS ◽  
1985 ◽  
Vol 76 (5) ◽  
pp. 851-852
Author(s):  
DONALD P. FRANCIS

Hepatitis B virus (HBV)-related diseases, which include acute hepatitis, chronic hepatitis and cirrhosis, and primary liver cancer, are major problems throughout much of the world. During the past several years, safe and effective HBV vaccines have been produced that have opened the way for the eventual control of these diseases. Although of use throughout the world, the greatest need for HBV vaccine is in east Asia and subsaharan Africa where the vast majority of the population is infected with this virus by early adulthood.1 Early in HBV vaccine history, the late Dr Maupas and his colleagues2 showed that the control of HBV infection in the developing world was possible.


2016 ◽  
Vol 30 (5) ◽  
pp. 579-588 ◽  
Author(s):  
Po-Hung Chen ◽  
Berkeley N. Limketkai ◽  
Panagiotis Trilianos ◽  
Muge Pirtini-Cetingul ◽  
Tinsay A. Woreta ◽  
...  

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Narcisse P Komas ◽  
Souleyman Baï-Sepou ◽  
Alexandre Manirakiza ◽  
Josiane Léal ◽  
Aubin Béré ◽  
...  

2018 ◽  
Vol 21 (2) ◽  
pp. 0-0
Author(s):  
Nader Nemr ◽  
Rania Kishk ◽  
Mohamed Mandour ◽  
Mostafa Ragheb

2021 ◽  
Vol 2 (1) ◽  
pp. 35-41
Author(s):  
A Zakari ◽  
ED Jatau ◽  
VT Ma'an ◽  
ME Rumji ◽  
OD Damulak ◽  
...  

Hepatitis B virus (HBV) is a transfusion-transmissible pathogen that poses a significant threat to blood safety. The virus' burden is high in the general population and among blood donors in Sub-Saharan Africa, leading to more donor rejection; blood discards, and increased risk of contamination of the blood supply. Hepatitis B Virus is vaccine-preventable; increased burden of infection may suggest a gap in vaccination. The study aimed to assess the level of hepatitis B virus vaccine uptake and identify factors affecting uptake of the vaccine among voluntary non remunerated blood donors (VNRBD) in Jos, Nigeria. A survey was conducted at the National Blood Transfusion Service (NBTS), Jos, among consenting VNRBD aged between 18 and 65 years from October to December 2020 using a structured questionnaire to collect information on vaccination status, socio-demographics and others. Of the 120 VNRBD interviewed, 36.7% received one or more doses of the HBV vaccine, while the majority (63.3%) were unvaccinated. Among the unvaccinated donors, 57.9% were unaware that HBV has a vaccine, 21.1% did not know where to get the vaccine, 7.9% had no time to get vaccinated; 3.9 % believed that there was no need to get vaccinated because they tested negative for the virus, while 9.2% gave no reason. Our study found a low uptake of HBV vaccine among VNRBD in our environment. We advocate for increased awareness and strong legislation to ensure universal access to the vaccine by Nigerians.


2016 ◽  
Vol 35 (2) ◽  
pp. 47
Author(s):  
Somying Ngamurulert ◽  
Isaya Janwithayanuchit ◽  
Sumonrat Chuwongwattana ◽  
Suda Louisirirotchanakul ◽  
Prasert Auewarakul

Objective: To investigate the prevalence of hepatitis B virus (HBV) infection and to diagnose an occult HBV infection in healthy Thai subjects after implementation of the expanded program on immunization (EPI) in newborns.Material and Method: The detection of HBsAg, anti-HBs and anti-HBc was done from serum samples of 5,886 healthy first year students from Huachiew Chalermprakiet University collected between 2009-2011 by immunochro-matography rapid assay (Alcon, USA). In case of only anti-HBc positive, the results were confirmed with chemiluminescence enzyme immunoassay (EIA) method and then they were investigated further for HBV occult infection by nested polymerase chain reaction technique.Results: A total of 78% (4,593/5,886) healthy first year students who had been vaccinated with HBV vaccine since birth were found to have no HBV markers, while 18.4% (1,083/5,886) had only anti-HBs. The prevalence of infection was 3.6% (210/5,886). Identification of patterns of HBV infection among the 210 infected subjects found that (1) Immuned due to past infection was 61.9% (130/210) (2) Infected with hepatitis B virus was 38.1% (80/120). The prevalence of both HBsAg and anti-HBc was 28.6% (60/210), while the prevalences of HBsAg and Anti-HBc alone were 3.8% (8/210) and 5.7% (12/210), respectively. Anti-HBc alone group was repeated with chemiluminescence EIA and HBV DNA was negative.Conclusion: The prevalence of HBV infection was 3.6% (210/5,886), however, seropositive rate of HBV infection was 1.4% (80/5,886). Most antibodies from vaccination had substantially declined to the point that it was undetectable. Therefore, the overall study showed an effective implementation of EPI in newborns. 


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