scholarly journals Developing a core outcome domain set to assessing effectiveness of interdisciplinary multimodal pain therapy

Pain ◽  
2018 ◽  
Vol 159 (4) ◽  
pp. 673-683 ◽  
Author(s):  
Ulrike Kaiser ◽  
Christian Kopkow ◽  
Stefanie Deckert ◽  
Katrin Neustadt ◽  
Lena Jacobi ◽  
...  
Keyword(s):  
Pain Therapy ◽  
Core Outcome ◽  
Multimodal Pain Therapy ◽  
Outcome Domain ◽  
Interdisciplinary Multimodal Pain Therapy

Longitudinal resting-state electroencephalography in chronic pain patients undergoing interdisciplinary multimodal pain therapy

Pain ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Henrik Heitmann ◽  
Cristina Gil Ávila ◽  
Moritz M. Nickel ◽  
Son Ta Dinh ◽  
Elisabeth S. May ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Resting State ◽  
Pain Therapy ◽  
Multimodal Pain Therapy ◽  
Chronic Pain Patients ◽  
Interdisciplinary Multimodal Pain Therapy ◽  
Pain Patients

scholarly journals Impact of treatment dose on patient outcomes after Interdisciplinary Multimodal Pain Therapy

2021 ◽  
Author(s):  
Philipp Baumbach ◽  
Maria Richter ◽  
Johannes Schneider ◽  
Ulrich Christian Smolenski ◽  
Thomas Weiss ◽  
...  
Keyword(s):  
Pain Intensity ◽  
Pain Therapy ◽  
Low Dose ◽  
High Dose ◽  
Multimodal Pain Therapy ◽  
Average Pain Intensity ◽  
Average Pain ◽  
Interdisciplinary Multimodal Pain Therapy ◽  
The Impact

Abstract Objectives The impact of duration and intensity on outcomes after Interdisciplinary Multimodal Pain Therapy (IMPT) is poorly researched. The aim of this study was to compare the effects of low dose (LD, avg. 25 hours) and high dose IMPT (HD, avg. 110 hours).Methods Patients completed pain-related questionnaires at the beginning (T1), at the end of therapy (T2) and at 3-month follow-up (T3) and were matched according to age, sex, presence of back-pain and pain-related disability at T1, resulting in 32 patients per group. Primary endpoint was the difference in pain-related disability and average pain intensity at T3 between both groups. In addition, early treatment effects and group differences at T2 were analyzed.Results Both groups showed significant improvements in pain-related disability and average pain intensity between T1 and T2. These positive effects persisted in the HD group until the 3-month follow-up, whereas outcomes in the LD group patients deteriorated and were significantly poorer compared to HD at T3.Discussion Within a widely comparable therapeutic setting, high-dose IMPT was associated with longer lasting improvements compared to low-dose IMPT in chronic pain patients, indicating that the “dose” of therapy is a relevant factor for clinical outcomes and should be further investigated.

scholarly journals Core outcome set to assess effectiveness in multimodal pain therapy – preliminary results of an interdisciplinary online survey

Trials ◽  
2015 ◽  
Vol 16 (S1) ◽  
Author(s):  
Christian Kopkow ◽  
Stefanie Deckert ◽  
Jochen Schmitt ◽  
Rainer Sabatowski ◽  
Ulrike Kaiser
Keyword(s):  
Online Survey ◽  
Pain Therapy ◽  
Core Outcome Set ◽  
Core Outcome ◽  
Multimodal Pain Therapy ◽  
Preliminary Results ◽  
Outcome Set

scholarly journals Engaging Stakeholders and Promoting Uptake of OMERACT Core Outcome Instrument Sets

2017 ◽  
Vol 44 (10) ◽  
pp. 1551-1559 ◽  
Author(s):  
Sean R. Tunis ◽  
Lara J. Maxwell ◽  
Ian D. Graham ◽  
Beverley J. Shea ◽  
Dorcas E. Beaton ◽  
...  
Keyword(s):  
Knowledge Translation ◽  
Core Outcome Set ◽  
Healthcare Providers ◽  
Stakeholder Involvement ◽  
Decision Makers ◽  
Core Outcome ◽  
Core Outcome Sets ◽  
Regulatory Decision ◽  
Outcome Instrument ◽  
Outcome Domain

Objective.While there has been substantial progress in the development of core outcomes sets, the degree to which these are used by researchers is variable. We convened a special workshop on knowledge translation at the Outcome Measures in Rheumatology (OMERACT) 2016 with 2 main goals. The first focused on the development of a formal knowledge translation framework and the second on promoting uptake of recommended core outcome domain and instrument sets.Methods.We invited all 189 OMERACT 2016 attendees to the workshop; 86 attended, representing patient research partners (n = 15), healthcare providers/clinician researchers (n = 52), industry (n = 4), regulatory agencies (n = 4), and OMERACT fellows (n = 11). Participants were given an introduction to knowledge translation and were asked to propose and discuss recommendations for the OMERACT community to (1) strengthen stakeholder involvement in the core outcome instrument set development process, and (2) promote uptake of core outcome sets with a specific focus on the potential role of post-regulatory decision makers.Results.We developed the novel “OMERACT integrated knowledge translation” framework, which formalizes OMERACT’s knowledge translation strategies. We produced strategies to improve stakeholder engagement throughout the process of core outcome set development and created a list of creative and innovative ways to promote the uptake of OMERACT’s core outcome sets.Conclusion.The guidance provided in this paper is preliminary and is based on the views of the participants. Future work will engage OMERACT groups, “post-regulatory decision makers,” and a broad range of different stakeholders to identify and evaluate the most useful methods and processes, and to revise guidance accordingly.

Multimodal pain therapy in chronic noncancer pain—gold standard or need for further clarification?

Pain ◽  
2017 ◽  
Vol 158 (10) ◽  
pp. 1853-1859 ◽  
Author(s):  
Ulrike Kaiser ◽  
Rolf-Detlef Treede ◽  
Rainer Sabatowski
Keyword(s):  
Gold Standard ◽  
Pain Therapy ◽  
Multimodal Pain Therapy ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

scholarly journals A Meta-Epidemiological Appraisal of the Effects of Interdisciplinary Multimodal Pain Therapy Dosing for Chronic Low Back Pain

2019 ◽  
Vol 8 (6) ◽  
pp. 871 ◽  
Author(s):  
Dragioti ◽  
Björk ◽  
Larsson ◽  
Gerdle
Keyword(s):  
Pain Therapy ◽  
Meta Analysis ◽  
Low Back ◽  
Low Intensity ◽  
Daily Contact ◽  
Interdisciplinary Multimodal Pain Therapy ◽  
Meta Regression ◽  
Meta Regression Analysis ◽  
Intensity Of Treatment

Using a meta-analysis, meta-regression, and a meta-epidemiological approach, we conducted a systematic review to examine the influence of interdisciplinary multimodal pain therapy (IMPT) dosage on pain, disability, return to work, quality of life, depression, and anxiety in published randomised controlled trials (RCTs) in patients with non-specific chronic low back pain (CLBP). We considered all RCTs of IMPT from a Cochrane review and searched PubMed for additional RCTs through 30 September 2018. A subgroup random-effects meta-analysis by length, contact, and intensity of treatment was performed followed by a meta-regression analysis. Using random and fixed-effect models and a summary relative odds ratio (ROR), we compared the effect sizes (ES) from short-length, non-daily contact, and low-intensity RCTs with long-length, daily contact, and high-intensity RCTs. Heterogeneity was quantified with the I2 metric. A total of 47 RCTs were selected. Subgroup meta-analysis showed that there were larger ES for pain and disability in RCTs with long-length, non-daily contact, and low intensity of treatment. Larger ES were also observed for quality of life in RCTs with short-length, non-daily contact, and low intensity treatment. However, these findings were not confirmed by the meta-regression analysis. Likewise, the summary RORs were not significant, indicating that the length, contact, and intensity of treatment did not have an overall effect on the investigated outcomes. For the outcomes investigated here, IMPT dosage is not generally associated with better ES, and an optimal dosage was not determined.

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