scholarly journals Eosinopenia as predictor of infection in patients admitted to an internal medicine ward: a cross-sectional study

2020 ◽  
Vol 5 (6) ◽  
pp. e084
Author(s):  
João M. Silva ◽  
Artur M. Costa ◽  
Célia Tuna ◽  
Renato Gonçalves ◽  
Sara Ferreira ◽  
...  
BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e030515
Author(s):  
Junpei Komagamine ◽  
Masaki Kobayashi

ObjectivesFew studies have investigated the prevalence of adverse drug reactions (ADRs) leading to hospitalisation in Japan. The aim of this study was to determine the prevalence of ADRs leading to hospitalisation and to evaluate the preventability of these ADRs in Japan.DesignA single-centre cross-sectional study using electronic medical records.SettingAcute care hospital.ParticipantsAll 1545 consecutive hospital admissions to an internal medicine ward due to acute medical illnesses from April 2017 to May 2018. The median patient age was 79 years (IQR 66–87), and the proportion of women was 47.9%.Outcome measuresThe primary outcome was the proportion of hospitalisations caused by ADRs among all hospitalisations. All suspected cases of ADRs were independently evaluated by two reviewers, and disagreements were resolved by discussion. The causality assessment for ADRs was performed by using the WHO-Uppsala Monitoring Committee criteria. The contribution of ADRs to hospitalisation and their preventability were evaluated based on the Hallas criteria.ResultsOf the 1545 hospitalisations, 153 hospitalisations (9.9%, 95% CI 8.4% to 11.4%) were caused by 200 ADRs. Cardiovascular agents (n=46, 23.0%), antithrombic agents (n=33, 16.5%), psychotropic agents (n=29, 14.5%) and non-steroidal anti-inflammatory drugs (n=24, 12.0%) accounted for approximately two-thirds of all ADRs leading to hospitalisation. Of 153 hospitalisations caused by ADRs, 102 (66.7%) were judged to be preventable.ConclusionsSimilar to other countries, one in every ten hospitalisations is caused by ADRs according to data from an internal medicine ward of a Japanese hospital. Most of these hospitalisations are preventable. Some efforts to minimise hospitalisations caused by ADRs are needed.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Marc-Antoine Bornet ◽  
Eve Rubli Truchard ◽  
Gérard Waeber ◽  
Peter Vollenweider ◽  
Mathieu Bernard ◽  
...  

Abstract Background Elderly people frequently express the wish to die: this ranges from a simple wish for a natural death to a more explicit request for death. The frequency of the wish to die and its associated factors have not been assessed in acute hospitalization settings. This study aimed to investigate the prevalence and determinants of the wish to die in elderly (≥65 years) patients hospitalized in an internal medicine ward. Methods This cross-sectional study was conducted between 1 May, 2018, and 30 April, 2019, in an acute care internal medicine ward in a Swiss university hospital. Participants were a consecutive sample of 232 patients (44.8% women, 79.3 ± 8.1 years) with no cognitive impairment. Wish to die was assessed using the Schedule of Attitudes toward Hastened Death-senior and the Categories of Attitudes toward Death Occurrence scales. Results Prevalence of the wish to die was 8.6% (95% confidence interval [CI]: 5.3–13.0). Bivariate analysis showed that patients expressing the wish to die were older (P = .014), had a lower quality of life (P < .001), and showed more depressive symptoms (P = .044). Multivariable analysis showed that increased age was positively (odds ratio [OR] for a 5-year increase: 1.43, 95% CI 0.99–2.04, P = .048) and quality of life negatively (OR: 0.54, 95% CI 0.39–0.75, P < 0.001) associated with the likelihood of wishing to die. Participants did not experience stress during the interview. Conclusions Prevalence of the wish to die among elderly patients admitted to an acute hospital setting is low, but highly relevant for clinical practice. Older age increases and better quality of life decreases the likelihood of wishing to die. Discussion of death appears to be well tolerated by patients.


CMAJ Open ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. E1021-E1025
Author(s):  
Michael Fralick ◽  
Neal Kaw ◽  
Mingkun Wang ◽  
Muhammad Mamdani ◽  
Ophyr Mourad

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Muhammad Tariq ◽  
Afaq Motiwala ◽  
Syed Umer Ali ◽  
Mehmood Riaz ◽  
Safia Awan ◽  
...  

BMJ Open ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. e013898 ◽  
Author(s):  
Thomas V Perneger ◽  
Antoine Poncet ◽  
Marc Carpentier ◽  
Thomas Agoritsas ◽  
Christophe Combescure ◽  
...  

2022 ◽  
Vol 71 (12) ◽  
Author(s):  
Sana Javed ◽  
Muhammad Zaid ◽  
Sumera Imran ◽  
Ayesha Hai ◽  
Muhammad Junaid Patel

Objective: To estimate the frequency of patients with fibromyalgia (by using the 2010 Modified Criteria for Fibromyalgia by American College of Rheumatology ( ACR ) presenting to Internal Medicine clinics  Methods: A cross-sectional study conducted in the department of Internal Medicine, the Indus Hospital, khi, Pakistan between December 2016 and March 2018. Patients who visited internal medicine clinics, met the selection criteria, were included in the study. After taking informed consent patients were assessed for fibromyalgia according to the new 2010 Fibromyalgia Diagnostic criteria questionnaire. The patients were asked the questions in the national language, Urdu. Data analyzed using SPSS version 21. P value of < 0.05 was considered significant. Results: Of the 267 patients presenting to the internal medicine clinics and consenting for participating in the study 149 (55.80%) met at least one of the 2010 Fibromyalgia Criteria. The prevalence of fibromyalgia as estimated in this study was 56% with no difference in gender. Mean age of patients with fibromyalgia was 42.3 ± 14.6 and patients without fibromyalgia was 38.9 ± 13.7 which was statistically significant (p-value = 0.05, 10% level of significance). Of the 267 patient 197 (73.8%) were female and 70 (26.2%) were males, a male to female ratio of 1:2.81.  Conclusion: All patients with generalized pain should be evaluated for fibromyalgia and a diagnosis made to reduce the cost of further referrals and investigations and delay in the management of this debilitating disorder. Keywords: Fibromyalgia, Chronic fatigue, Generalized Pain  


2018 ◽  
Vol 14 (2) ◽  
pp. 117
Author(s):  
Charles P. Opperman, MD ◽  
Melissa M. Butler, MD ◽  
Andrew K. Stroud, MD ◽  
Michael R. Sun, MD

A retrospective, cross-sectional study was completed on 220 patients to determine the effects of implementation of an aggressive policy to curb opioid misuse/abuse in an internal medicine residency clinic. Our findings suggest that the development of a clear and consistent protocol for approaching patients on chronic controlled substances, as well as the initiation of regular didactic sessions addressing chronic pain and pain management, led to a dramatic reduction in the number or opioid prescriptions written by our resident providers without much reduction in patient volume.


CMAJ Open ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. E47-E54 ◽  
Author(s):  
Amol A. Verma ◽  
Yishan Guo ◽  
Janice L. Kwan ◽  
Lauren Lapointe-Shaw ◽  
Shail Rawal ◽  
...  

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