scholarly journals Spiral Ganglion Cell Loss Is Unrelated to Segmental Cochlear Sensory System Degeneration in Humans

2009 ◽  
Vol 30 (3) ◽  
pp. 418-422 ◽  
Author(s):  
Fred H. Linthicum ◽  
Jose N. Fayad
Keyword(s):  
Ganglion Cell ◽  
Spiral Ganglion ◽  
Sensory System ◽  
Cell Loss ◽  
Spiral Ganglion Cell ◽  
System Degeneration

scholarly journals Neurotrophins can enhance spiral ganglion cell survival after inner hair cell loss

1997 ◽  
Vol 15 (4-5) ◽  
pp. 631-643 ◽  
Author(s):  
Josef M. Miller ◽  
David H. Chi ◽  
Leonard J. O'Keeffe ◽  
Paul Kruszka ◽  
Yehoash Raphael ◽  
...  
Keyword(s):  
Hair Cell ◽  
Ganglion Cell ◽  
Cell Survival ◽  
Spiral Ganglion ◽  
Cell Loss ◽  
Hair Cell Loss ◽  
Inner Hair Cell ◽  
Spiral Ganglion Cell

Synaptic alterations at inner hair cells precede spiral ganglion cell loss in aging C57BL/6J mice

2006 ◽  
Vol 221 (1-2) ◽  
pp. 104-118 ◽  
Author(s):  
Sofia Stamataki ◽  
Howard W. Francis ◽  
Mohamed Lehar ◽  
Bradford J. May ◽  
David K. Ryugo
Keyword(s):  
Ganglion Cell ◽  
Hair Cells ◽  
Spiral Ganglion ◽  
Cell Loss ◽  
Inner Hair Cells ◽  
Spiral Ganglion Cell

Diameter of the Cochlear Nerve in Deaf Humans: Implications for Cochlear Implantation

1992 ◽  
Vol 101 (12) ◽  
pp. 988-993 ◽  
Author(s):  
Joseph B. Nadol ◽  
Wen-Zhuang Xu
Keyword(s):  
Ganglion Cell ◽  
Cell Count ◽  
Cochlear Implantation ◽  
Ganglion Cells ◽  
Cranial Nerves ◽  
Spiral Ganglion ◽  
Normal Hearing ◽  
Maximum Diameter ◽  
Eighth Nerve ◽  
Spiral Ganglion Cell

Although the parameters that are most important for postoperative speech perception in cochlear implantation have not been identified, it is assumed that the numbers of remaining cochlear neurons and spiral ganglion cells in the implanted deaf ears are critical. In this study, we evaluated the correlation of the maximum diameter of the cochlear and vestibular nerve trunks with the number of spiral ganglion cells in horizontal sections of the temporal bone of 42 patients who were profoundly deaf during life, and in 5 patients with normal hearing. The maximum diameters of the cochlear, vestibular, and eighth cranial nerves were significantly smaller in the deaf population as compared to normal-hearing controls. In addition, the counts of the remaining spiral ganglion cells were significantly correlated with the maximum diameter of the cochlear (p = .0006), vestibular (p = .001), and eighth cranial nerves (p = .0003). The regression equation estimated that 25% of the variance of the spiral ganglion cell count was predicted by the maximum diameter of the eighth nerve. Although the results of this study suggest that preoperative radiographic imaging of the diameter of the eighth nerve may be helpful in predicting the residual spiral ganglion cell count, the wide variability of diameters of the eighth nerve in hearing and deaf subjects militates against this theoretic usefulness.

scholarly journals Effects of delayed treatment with combined GDNF and continuous electrical stimulation on spiral ganglion cell survival in deafened guinea pigs

2009 ◽  
Vol 87 (6) ◽  
pp. 1389-1399 ◽  
Author(s):  
Verena Scheper ◽  
Gerrit Paasche ◽  
Josef M. Miller ◽  
Athanasia Warnecke ◽  
Nurdanat Berkingali ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Ganglion Cell ◽  
Cell Survival ◽  
Guinea Pigs ◽  
Spiral Ganglion ◽  
Delayed Treatment ◽  
Spiral Ganglion Cell
Sign in / Sign up

Export Citation Format

Share Document