scholarly journals Carbon nanoparticles facilitate lymph nodes dissection and parathyroid glands identification in reoperation of papillary thyroid cancer

Medicine ◽  
2017 ◽  
Vol 96 (44) ◽  
pp. e8380 ◽  
Author(s):  
An-Ping Su ◽  
Bin Wang ◽  
Yan-Ping Gong ◽  
Wen-Shuang Wu ◽  
Ri-Xiang Gong ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Carbon Nanoparticles ◽  
Parathyroid Glands ◽  
Papillary Thyroid ◽  
Lymph Nodes Dissection

Potential Role of Carbon Nanoparticles in Guiding Central Neck Dissection and Protecting Parathyroid Glands in Patients with Papillary Thyroid Cancer

2019 ◽  
Vol 15 (3) ◽  
pp. 254-259
Author(s):  
Zhiliang Xu ◽  
Zhiyu Li ◽  
Qi Wu ◽  
Yimin Zhang ◽  
Shan Zhu ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Lymph Node Dissection ◽  
Parathyroid Glands ◽  
Control Group ◽  
Papillary Thyroid ◽  
Node Dissection

Background: Carbon nanoparticle (CN) suspensions have been widely used as lymph node tracers in cancers. Here, CN suspension was successfully applied to lymph node dissection. Objective: This study aimed to evaluate the role of CN suspension in identifying lymph nodes and preserving the parathyroid in patients with papillary thyroid cancer (PTC). Method: A total of 96 PTC patients were divided into a CN group (n = 46) and a control group (n = 50). All patients underwent total thyroidectomy with central lymph node dissection from 2014 to 2015. Results: The number of lymph nodes removed in the CN group and the control group was 9.6±2.4 and 7.8±2.2, respectively, and the number of dissected lymph nodes identified as <5 mm in both groups was 4.4±1.3 and 2.4±1.4, respectively. These results were significantly different between the two groups (P < 0.05). However, the number of metastatic lymph nodes was similar in the two groups. In addition, the results further revealed that the level of serum parathyroid hormone (PTH) was significantly lower in the control group than in the CN group on postoperative day 1 and week 1 (P < 0.05), but similar outcomes were observed at postoperative month 1. Conclusion: CN suspension plays an important role in accurately identifying lymph nodes and protecting parathyroid glands. The clinical utilization of CN suspension could increase the accuracy of surgery programs and protect parathyroid function.

Use of carbon nanoparticles to identify parathyroid glands at thyroidectomy for patients of papillary thyroid cancer.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e17006-e17006
Author(s):  
Anping Su ◽  
Tao Wei ◽  
Feng Liu ◽  
Yanping Gong ◽  
Yu Ma ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Carbon Nanoparticles ◽  
Parathyroid Glands ◽  
Papillary Thyroid

scholarly journals Potential role of carbon nanoparticles in protection of parathyroid glands in patients with papillary thyroid cancer

Medicine ◽  
2016 ◽  
Vol 95 (42) ◽  
pp. e5002 ◽  
Author(s):  
Wenbin Yu ◽  
Lijun Zhu ◽  
Guohui Xu ◽  
Yuntao Song ◽  
Guojun Li ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Carbon Nanoparticles ◽  
Potential Role ◽  
Parathyroid Glands ◽  
Papillary Thyroid

QUANTITATIVE AND QUALITATIVE CHARACTERISTICS OF METASTASES IN REGIONAL LYMPH NODES - RISK FACTORS FOR THE RECURRENCE OF PAPILLARY THYROID CANCER IN CHILDREN AND ADOLESCENTS

2018 ◽  
Vol 64 (2) ◽  
pp. 159-165
Author(s):  
Mikhail Fridman ◽  
Svetlana Mankovskaya ◽  
Olga Krasko
Keyword(s):  
Risk Factors ◽  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Children And Adolescents ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid ◽  
Regional Lymph Nodes ◽  
Cancer In Children ◽  
Qualitative Characteristics

Among the factors determining the relapse/persistence of papillary thyroid cancer in children and adolescents the most important are the age of the patient (p= 0.003), the presence of concomitant background pathology (p

scholarly journals Thyroglobulin measurements in washout of fine needle aspirates in cervical lymph nodes for detection of papillary thyroid cancer metastases

2010 ◽  
Vol 54 (6) ◽  
pp. 550-554 ◽  
Author(s):  
André B. Zanella ◽  
Erika L. Souza Meyer ◽  
Letícia Balzan ◽  
Antônio C. Silva ◽  
Joíza Camargo ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Needle Aspiration ◽  
Papillary Thyroid ◽  
Cervical Lymph Nodes ◽  
Fine Needle ◽  
Fine Needle Aspirates ◽  
Cancer Metastases ◽  
Thyroid Cancer Metastases

OBJECTIVE: The aim of this study was to evaluate the accuracy of the measurement of thyroglobulin in washout needle aspiration biopsy (FNAB-Tg) to detect papillary thyroid cancer (PTC) metastases. SUBJECTS AND METHODS: Forty-three patients (51.4 ± 14.6 years) with PTC diagnosis and evidence of enlarged cervical lymph nodes (LN) were included. An ultrasound-guided fine-needle aspiration of suspicious LN was performed, for both cytological examination and measurement of FNAB-Tg. RESULTS: The median values of FNAB-Tg in patients with metastatic LN (n = 5) was 3,419 ng/mL (11.1-25,538), while patients without LN metastasis (n = 38) showed levels of 3.7 ng/mL (0.8-7.4). Considering a 10 ng/mL cutoff value for FNAB-Tg, the sensitivity and specificity was 100%. There were no differences on the median of FNAB-Tg measurements between those on (TSH 0.07 mUI/mL) or off levothyroxine (TSH 97.4 mUI/mL) therapy (3.3 vs. 3.8 ng/mL, respectively; P = 0.2). CONCLUSION: The results show that evaluation of FNAB-Tg in cervical LN is a valuable diagnostic tool for PTC metastases that can be used independent of the thyroid status.

scholarly journals The association between tumor’s location and cervical lymph nodes metastasis in papillary thyroid cancer

Gland Surgery ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 557-568 ◽  
Author(s):  
Ting-Ting Zhang ◽  
Xiu-Zhu Qi ◽  
Jian-Ping Chen ◽  
Rong-Liang Shi ◽  
Shi-Shuai Wen ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid ◽  
Cervical Lymph Nodes ◽  
Lymph Nodes Metastasis

scholarly journals Elastography as a Potential Modality for Screening Cervical Lymph Nodes in Patients with Papillary Thyroid Cancer: A Review of Literature

2018 ◽  
Vol 97 (1-2) ◽  
pp. 31-39 ◽  
Author(s):  
Robert Saadi ◽  
Salvatore LaRusso ◽  
Kanupriya Vijay ◽  
David Goldenberg
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Clinical Utility ◽  
Lymph Node Involvement ◽  
Papillary Thyroid ◽  
Ultrasound Technique ◽  
Cervical Lymph Nodes ◽  
Specific Patient ◽  
Clinical Criteria

Papillary thyroid cancer often presents with cervical lymph node involvement and has a high incidence of recurrence, which requires routine follow-up with ultrasound imaging. Elastography is a novel ultrasound technique that has been demonstrated to be effective clinically in detecting tissue pathology in areas such as the liver and breast. Preliminary data suggest that it may be effective in screening tissues in the neck for malignancy, specifically cervical lymph nodes. However, diagnostic criteria and elastographic techniques vary significantly among the studies we have reviewed, which all tend to focus on populations of patients with many different types of primary malignancies. Further research is required on the feasibility of creating standardized and reproducible clinical criteria in a specific patient population. To study the clinical utility of elastography in cervical lymph nodes, patients with diagnosed papillary thyroid carcinoma may serve as an ideal population because of their need for ultrasound surveillance and the propensity of papillary thyroid cancer to metastasize to and recur in cervical lymph nodes. We will review the limitations, techniques, and reported clinical utility of elastography on cervical lymph nodes and its potential as a screening modality for papillary thyroid cancer.

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