Prevalence triggers and clinical severity associated with anaphylaxis at a tertiary care facility in Saudi Arabia

Background: Bipolar Disorders (BD) in youth are a heterogeneous condition with different phenomenology, patterns of comorbidity and outcomes. Our aim was to explore the effects of gender; age at onset (prepubertal- vs. adolescent-onset) of BD; and elements associated with attention deficit hyperactivity disorder (ADHD) and Substance Use Disorder (SUD) comorbidities, severe suicidal ideation or attempts, and poorer response to pharmacological treatments. Method: 117 youth (69 males and 57 females, age range 7 to 18 years, mean age 14.5 ± 2.6 years) consecutively referred for (hypo)manic episodes according to the Diagnostic and Statistical Manual of Mental Disorders, 54th ed (DSM 5) were included. Results: Gender differences were not evident for any of the selected features. Prepubertal-onset BD was associated with higher rates of ADHD and externalizing disorders. SUD was higher in adolescent-onset BD and was associated with externalizing comorbidities and lower response to treatments. None of the selected measures differentiated patients with or without suicidality. At a 6-month follow up, 51.3% of the patients were responders to treatments, without difference between those receiving and not receiving a psychotherapy. Clinical severity at baseline and comorbidity with Conduct Disorder (CD) and SUD were associated with poorer response. Logistic regression indicated that baseline severity and number of externalizing disorders were associated with a poorer outcome. Conclusions: Disentangling broader clinical conditions in more specific phenotypes can help timely and focused preventative and therapeutic interventions.

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Clostridioides difficile infection: Incidence and risk factors in a tertiary care facility in Riyadh, Saudi Arabia

Journal of Infection and Public Health ◽

10.1016/j.jiph.2019.10.014 ◽

2020 ◽

Vol 13 (7) ◽

pp. 1012-1017

Author(s):

Sally Alzouby ◽

Kamran Baig ◽

Fahad Alrabiah ◽

Atef Shibl ◽

Daifallah Al-Nakhli ◽

...

Keyword(s):

Risk Factors ◽

Saudi Arabia ◽

Tertiary Care ◽

Care Facility ◽

Infection Incidence ◽

Clostridioides Difficile ◽

Tertiary Care Facility ◽

Clostridioides Difficile Infection

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Assessing Acute St-Elevation Myocardial Infarction With Prognostic Significance Of The Hyponatramia

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11i3.2445 ◽

2020 ◽

Vol 11 (3) ◽

pp. 3251-3260

Author(s):

Makrand B Mane

Keyword(s):

Myocardial Infarction ◽

Ejection Fraction ◽

Tertiary Care ◽

Prognostic Significance ◽

Care Facility ◽

Early Death ◽

Public Health Issue ◽

Care Hospital ◽

Tertiary Care Facility ◽

Significant Public Health

Acute Myocardial Infarction (AMI) has become a significant public health issue in developed and developing nations, following extensive diagnostic and management research over recent decades. The study intended to research the prognostic values of inexplicable Hyponatremia in patients with severe STelevation of myocardial infarction, in 100 consecutive patients admitted to Tertiary care hospital. In the analysis, identified patients on admission were diagnosed with or produced Hyponatremia within 72 hours—a lower ejection fraction than those with usual amounts of sodium. The research aimed to evaluate the prognosis significance of Hyponatremia for the estimation of early death in acute ST-elevated myocardial infarction. One hundred straight patients admitted in the Coronary Centre Tertiary Care Facility with severe STelevated myocardial infarction were studied. The data of the study on various risk factors in association with the development of Hyponatremia like as age, sex, use of tobacco, diabetes, hypertension, ejection fraction etc. were analyzed. Thus, the researchers reported that in patients diagnosed with severe ST section escalation, Hyponatremia showed the initial emergence of hyponatremia myocardial infarctions. This condition correlates with the severity of LV dysfunction (in term of LVEF) and can be considered as an individual early death indicator as well as a prediction exacerbates with hyponatremia frequency.

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